A new stilbene dimer--shegansu B from Belamcanda chinensis.

abstract：:A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two pr...

journal_title：Journal of Asian natural products research

authors： Zhang HJ,Yang XP,Wang KW

更新日期：2010-04-01 00:00:00

abstract：:Resveratrol (3,4',5-trihydroxy-trans-silbene), a natural phytoalexin found in grapes and other food products, has promising anti-inflammatory and anticancer effects. To observe the modulation of interleukin-8 (IL-8) production in human monocytic cells by resveratrol and explore its mechanism at the gene transcription ...

journal_title：Journal of Asian natural products research

authors： Shen F,Chen SJ,Dong XJ,Zhong H,Li YT,Cheng GF

更新日期：2003-06-01 00:00:00

abstract：:Carpesides A (1) and B (2), two new 8-O-4'-neolignan glucosides, and eupatriol 9-O-beta-d-apiofuranosyl-(1 --> 6)-beta-d-glucopyranoside (3), one new monoterpenoid diglycoside, together with 10 known glycosidic compounds, were isolated from the aerial part of Carpesium cernuum L. The structures of the new glycosides a...

journal_title：Journal of Asian natural products research

authors： Ma JP,Tan CH,Zhu DY

更新日期：2008-05-01 00:00:00

abstract：:Five labdane-type diterpenes, vitexilactone (1), (rel 5S,6R,8R,9R,10S)-6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (2), rotundifuran (3), vitetrifolin D (4), and vitetrifolin E (5), have been isolated from Vitex trifolia L., a Chinese folk medicine used to treat cancers, as new cell cycle inhibitors and apoptosis in...

journal_title：Journal of Asian natural products research

authors： Li WX,Cui CB,Cai B,Yao XS

更新日期：2005-04-01 00:00:00

abstract：:Two new sesquiterpene derivatives, (+)-8β-hydroxy-longicamphenylone (1) and 11β-hydroxy-13-isopropyl-dihydrodehydrocostus lactone (2), were isolated from Chinese eaglewood. Their structures were elucidated on the basis of spectroscopic analyses including HR-ESI-MS, (1)H and (13)C NMR, DEPT, (1)H-(1)H COSY, HSQC, HMBC,...

journal_title：Journal of Asian natural products research

authors： Yang L,Qiao LR,Zhang JJ,Dai JG,Guo SX

更新日期：2012-01-01 00:00:00

abstract：:A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain...

journal_title：Journal of Asian natural products research

authors： Xie XL,Ye GH,Xue JJ,Su T,Tang GH,Li W,Yin S

更新日期：2020-05-01 00:00:00

abstract：:Suberoylanilide hydroxamic acid (1), as well as other histone deacetylase (HDAC) inhibitors, are promising, targeted anticancer agents. Curcumin (2), a possible antitumor agent, exhibits a HDAC inhibiting effect but with a different mechanism, and was proposed to synergize with other drugs, including HDAC inhibitors. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Lu N,Yan Z,Wang N

更新日期：2010-05-01 00:00:00

abstract：:Two new 3,4-seco-lanostane-type triterpenes, named as 15α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1), 5α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid 3-methyl ester (2), and one new lanostane triterpene 15α-acetoxylhydroxytrametenolic acid (3) together with a known one versisponic aci...

journal_title：Journal of Asian natural products research

authors： Yin X,Li ZH,Li Y,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:Three new xanthone glycosides, securixanside A (1), securixanside B (2), and securixanside C (3) were isolated from the stems of Securidaca inappendiculata. These compounds were characterized by spectrometric and chemical methods, including FABMS and one- and two-dimensional NMR experiments. ...

journal_title：Journal of Asian natural products research

authors： Yang XD,An N,Xu LZ,Yang SL

更新日期：2002-06-01 00:00:00

abstract：:Thiazinogeldanamycin (2) was identified from Streptomyces hygroscopicus 17997 at the late stage of the fermentation. The pH was firstly proposed as an important factor in the biosynthesis of it. It was verified that 2 was produced by direct chemical reactions between geldanamycin (1, GDM) and cysteine or aminoethaneth...

journal_title：Journal of Asian natural products research

authors： Liu YF,Zhong JJ,Lin L,Liu JJ,Wang YG,He WQ,Yang ZY

更新日期：2016-08-01 00:00:00

abstract：:Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

journal_title：Journal of Asian natural products research

authors： Hua F,Shang S,Hu ZW

更新日期：2017-04-01 00:00:00

abstract：:Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

journal_title：Journal of Asian natural products research

authors： Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

更新日期：2009-06-01 00:00:00

abstract：:Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...

journal_title：Journal of Asian natural products research

authors： Ma X,Jiang L,Zhu MH,Liu CH,Wang GC,Li YT,Liu T,Li YJ

更新日期：2021-01-19 00:00:00

abstract：:A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of ...

journal_title：Journal of Asian natural products research

authors： Zhao W,Deng AJ,Du GH,Zhang JL,Li ZH,Qin HL

更新日期：2009-01-01 00:00:00

abstract：:A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...

journal_title：Journal of Asian natural products research

authors： Chai MY

更新日期：2020-03-01 00:00:00

abstract：:Two new guaianolides artemanomalides A and B were isolated from the aerial parts of Artemisia anomala S. Moore. Their structures were characterized as 2-oxo-5α, 10α-dihydroxy-guaia-3-en-1α, 6β, 7α, 11β H-12, 6-olide (1) and 8α-acetoxy-2-oxo-5α, 10α-dihydroxy-guaia-3, 11(13)-dien-1α, 6β, 7αH-12, 6-olide (2) on the basi...

journal_title：Journal of Asian natural products research

authors： Hu ZH,Zhang P,Huang DB,Wu JZ

更新日期：2012-01-01 00:00:00

abstract：:Two new sesquiterpene pyridine alkaloids, Chinese bittersweet alkaloid A (1) and Chinese bittersweet alkaloid B (2), together with five known compounds 3β- hydroxyolean-9(11),12-diene, β-sitosterol, 1β,2β,6α,15β-tetraacetoxy-8β,9α- dibenzoyloxy-β-dihydroagarofuran, angulatin A and angulatin J, were isolated from the r...

journal_title：Journal of Asian natural products research

authors： Chang X,Wang ZY,Chen X,Ma YN,Zhang HY,Zhao TZ

更新日期：2019-11-01 00:00:00

abstract：:Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

journal_title：Journal of Asian natural products research

authors： Li J,Wang XL,Wang AP,Xu SF,Jin HT

更新日期：2017-04-01 00:00:00

abstract：:Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

journal_title：Journal of Asian natural products research

authors： Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

更新日期：2015-01-01 00:00:00

abstract：:Two new dammarane-type triterpenoid saponins, namely ginsenoside Rk6 (1) and ginsenoside-Rh22 (2), were isolated from notoginseng medicinal fungal substance. The structures of 1 and 2 were established as 3β,6α,12β,26-tetrahydroxydammar-20(21),24(25)(E)-diene-6-O-β-D-glucopyranoside and 3β,6α, 20(S)-trihydroxy-12(R),23...

journal_title：Journal of Asian natural products research

authors： Xu W,Liu X,Liu XL,Jia AL,Wang XW,Qiu ZD

更新日期：2016-12-01 00:00:00

abstract：:The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be a new strategy for treating epilepsy. So far, no studies have shown whether the ...

journal_title：Journal of Asian natural products research

authors： Peng YC,Wang S,Zhang Y,Huang LJ,Wang XL,Peng Y

更新日期：2019-09-01 00:00:00

abstract：:A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

journal_title：Journal of Asian natural products research

authors： Kong LY,Zhi F

更新日期：2003-09-01 00:00:00

abstract：:We present in this paper the efficient four-component one-pot synthesis of a fully protected hexaarabinogalactan 2 with di-branched structure by using D-thiogalactopyranoside 3,6-diol 3 as the central glycosylating agent. After global deprotection, 2 was converted into the 3-aminopropyl linker-containing free oligosac...

journal_title：Journal of Asian natural products research

authors： Huang H,Han L,Lan YM,Zhang LL

更新日期：2014-01-01 00:00:00

abstract：:A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, 1H and 13C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on...

journal_title：Journal of Asian natural products research

authors： Wu XA,Zhao YM,Yu NJ

更新日期：2006-09-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:Two new stemoninine-type alkaloids, stemoninine A (1) and B (2), along with two known Stemona alkaloids, bisdehydrostemoninine (3) and bisdehydrostemoninine A (4), were isolated from the roots of Stemona sessilifolia, and their structures and relative configurations were determined on the basis of spectrometric data a...

journal_title：Journal of Asian natural products research

authors： Wang P,Liu AL,Li ZH,Du GH,Qin HL

更新日期：2008-03-01 00:00:00

abstract：:Four new lignan glycosides (1-4), named procumbenosides I, K, L, and M, together with cleistanthin B (5) reported for the first time in the genus Justicia, and 5 other known arylnaphthalene lignan glycosides (6-10) were isolated from the whole plant of Justicia procumbens. The structures of the new compounds were eluc...

journal_title：Journal of Asian natural products research

authors： Jin H,Yang S,Dong JX

更新日期：2017-01-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...

journal_title：Journal of Asian natural products research

authors： Zhao MY,Yang XW

更新日期：2008-07-01 00:00:00

abstract：:Three new acetylated anthraquinone glycosides (1-3) were isolated from the seed of Cassia obtusifolia, together with one parent anthraquinone glycoside (1a). Their structures were determined on the basis of spectroscopic methods and physicochemical properties as obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1)...

journal_title：Journal of Asian natural products research

authors： Wu XH,Cai JJ,Ruan JL,Lou JS,Duan HQ,Zhang J,Cheng CR,Guo DA,Wu ZY,Zhang YW

更新日期：2011-06-01 00:00:00