One-pot synthesis of a 3,6-branched hexaarabinogalactan using galactopyranosyl thioglycoside diol as a key glycosylating agent.

Abstract:

:We present in this paper the efficient four-component one-pot synthesis of a fully protected hexaarabinogalactan 2 with di-branched structure by using D-thiogalactopyranoside 3,6-diol 3 as the central glycosylating agent. After global deprotection, 2 was converted into the 3-aminopropyl linker-containing free oligosaccharide 1 that is structurally related to ALR-5IIa-1-1, an arabino-3,6-galactan with intestinal immune system modulating activity.

journal_name

J Asian Nat Prod Res

authors

Huang H,Han L,Lan YM,Zhang LL

doi

10.1080/10286020.2014.917084

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

640-7

issue

6

eissn

1028-6020

issn

1477-2213

journal_volume

16

pub_type

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