A new bioactive coumestan from the seeds of Psoralea corylifolia.

abstract：:The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male...

journal_title：Journal of Asian natural products research

authors： Liu J,Hu G,Xu R,Qiao Y,Wu HP,Ding X,Duan P,Tu P,Lin YJ

更新日期：2013-07-01 00:00:00

abstract：:Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory...

journal_title：Journal of Asian natural products research

authors： Jiang JS,Li FS,Feng ZM,Yang YN,Zhang PC

更新日期：2020-01-01 00:00:00

abstract：:A new periplogenin cardenolide, periplogulcoside (1), together with three known cardenolides, was isolated from the seeds of Antiaris toxicaria. The structure of the new compound was characterized as periplogenin-3-O-β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranoside (1) by spectroscopic methods including 1D and 2D NMR, H...

journal_title：Journal of Asian natural products research

authors： Wu XL,Wu YL,Li HG,Liu HT,Fu XY,Cui RQ,Wang JH,Liu C,Chen J

更新日期：2014-01-01 00:00:00

abstract：:Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

journal_title：Journal of Asian natural products research

authors： Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

更新日期：2010-10-01 00:00:00

abstract：:A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

journal_title：Journal of Asian natural products research

authors： Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

更新日期：2012-01-01 00:00:00

abstract：:Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

journal_title：Journal of Asian natural products research

authors： Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

更新日期：2006-12-01 00:00:00

abstract：:A new diterpenoid alkaloid, racemulotine (1), was isolated from the whole plants of Aconitum racemulosum Franch var. pengzhouense, and its structure was elucidated by 1D- and 2D-NMR spectra. ...

journal_title：Journal of Asian natural products research

authors： Peng CS,Jian XX,Wang FP

更新日期：2001-01-01 00:00:00

abstract：:A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy...

journal_title：Journal of Asian natural products research

authors： Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JH

更新日期：2014-01-01 00:00:00

abstract：:A new p-coumaroylated santalane-type sesquiterpenoid, 8-p-coumaroyl-α-santalene (1), a new p-coumaroylated oplopanane-type sesquiterpenoid, 8-β-p-coumaroyl-oplopanone (2), and three known p-coumaroylated humulene-type sesquiterpenoids (3-5) were isolated from the ethanol extract of the whole herbs of Pilea cavaleriei....

journal_title：Journal of Asian natural products research

authors： Ren HC,Zhang J,Liang H

更新日期：2018-02-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...

journal_title：Journal of Asian natural products research

authors： Shi JX,Li YH,Wang X,Qin YQ,Zhang CY,Zhang X,Li CR,An MQ,Li LR,Lu SH,Huang J

更新日期：2018-11-01 00:00:00

abstract：:Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

journal_title：Journal of Asian natural products research

authors： Mu LH,Li JB,Yang JZ,Zhang DM

更新日期：2007-09-01 00:00:00

abstract：:Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

journal_title：Journal of Asian natural products research

authors： Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

更新日期：2003-06-01 00:00:00

abstract：:A new diarylheptanoid, along with five known diarylheptanoids, was isolated from the rhizomes of Alpinia officinarum (Zingiberaceae). The structure of the new compound was determined to be trans,trans-1(3'-methoxy-4'-hydroxyphenyl)-7-phenyl-5-ol-4,6-dien-3-heptanone on the basis of spectral and chemical evidence. ...

journal_title：Journal of Asian natural products research

authors： An N,Xu LZ,Zou ZM,Yang SL

更新日期：2006-10-01 00:00:00

abstract：:Two new indole alkaloids, tryptoquivalines R and S, have been isolated from a marine-derived fungus Neosartorya sp.HN-M-3. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR experiments. ...

journal_title：Journal of Asian natural products research

authors： Xu N,Cao Y,Wang L,Chen G,Pei YH

更新日期：2013-07-01 00:00:00

abstract：:Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

journal_title：Journal of Asian natural products research

authors： Jing WY,Jiang C,Ji F,Hua HM,Li ZL

更新日期：2013-11-01 00:00:00

abstract：:Our goals were to examine the dual-directional regulation effects of resveratrol (1) in vitro by using MCF-7 cells (estradiol receptor-positive cells), study its mechanism of action, and give a systematical analysis of the regulatory networks of each related factor. An MTT test and growth curve showed that the prolife...

journal_title：Journal of Asian natural products research

authors： Wang YZ,Cao B,Li SX,Zang ZH,Zhang JZ,Chen H

更新日期：2009-01-01 00:00:00

abstract：:Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 - 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts of Isodon taliensis. Their structures were elucidated based on the analyses of extensive spectroscopic d...

journal_title：Journal of Asian natural products research

authors： Xiang P,Xiao CJ,Xu W,Shan H,Qiu L,Li Y,Dong X,Jiang B

更新日期：2019-12-01 00:00:00

abstract：:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells an...

journal_title：Journal of Asian natural products research

authors： Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YH

更新日期：2009-09-01 00:00:00

abstract：:Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

journal_title：Journal of Asian natural products research

authors： Li J,Wang XL,Wang AP,Xu SF,Jin HT

更新日期：2017-04-01 00:00:00

abstract：:A series of novel tetrandrine (Tet) derivatives were synthesized through Suzuki -Miyaura reaction and evaluated for their cytotoxicity against human non-small cell lung carcinoma (NSCLC) A549 cells. Interestingly, most of derivatives showed similar cytotoxicity to Tet against NSCLC A549 cells, and particularly, compou...

journal_title：Journal of Asian natural products research

authors： Yang QH,Jiang CS,Jin T,Xu JF,Qu TL,Guo YW,Zhao ZB

更新日期：2018-11-01 00:00:00

abstract：:A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

journal_title：Journal of Asian natural products research

authors： Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

更新日期：2009-01-01 00:00:00

abstract：:The chemical investigation on the fruiting bodies of Amauroderma subresinosum led to the isolation of 10 compounds including 2 new ones named amaurosubresin (1) and erythro(23,24)-5α,6α-epoxyergosta-8-ene-7-one-3β,23-diol (2). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. T...

journal_title：Journal of Asian natural products research

authors： Wang Q,Wang YG,Ma QY,Huang SZ,Kong FD,Zhou LM,Dai HF,Zhao YX

更新日期：2016-11-01 00:00:00

abstract：:A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

journal_title：Journal of Asian natural products research

authors： Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

更新日期：2013-01-01 00:00:00

abstract：:One new flavone, 5,7-dihydroxy-8,2',3',6'-tetramethoxyflavone (1), and one new flavonol, 5,7,6'-trihydroxy-2'-methoxyflavonol (2), were isolated from the roots of Scutellaria baicalensis, and their structures were elucidated on the basis of extensive spectroscopic evidences, especially 1D and 2D NMR and HR-ESI-MS expe...

journal_title：Journal of Asian natural products research

authors： Long HL,Xu GY,Deng AJ,Li ZH,Ma L,Lu Y,Zhang ZH,Wu F,Qin HL

更新日期：2015-01-01 00:00:00

abstract：:Thiazinogeldanamycin (2) was identified from Streptomyces hygroscopicus 17997 at the late stage of the fermentation. The pH was firstly proposed as an important factor in the biosynthesis of it. It was verified that 2 was produced by direct chemical reactions between geldanamycin (1, GDM) and cysteine or aminoethaneth...

journal_title：Journal of Asian natural products research

authors： Liu YF,Zhong JJ,Lin L,Liu JJ,Wang YG,He WQ,Yang ZY

更新日期：2016-08-01 00:00:00

abstract：:Two new lignans named spicatolignan A (1) and spicatolignan B (2) have been isolated from the whole herbs of Mentha spicata L. ...

journal_title：Journal of Asian natural products research

authors： Zheng J,Chen GT,Gao HY,Wu B,Wu LJ

更新日期：2007-04-01 00:00:00

abstract：:Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

journal_title：Journal of Asian natural products research

authors： Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

更新日期：2009-06-01 00:00:00

abstract：:A new phenolic glycoside, 6'-[(E)-2''-hydroxymethyl, 2''-butenoyl] arbutin (1), and two known phenolic glycosides, 6'-[(E)-4''-hydroxycinnamoyl] arbutin (2) and 6'-[(E)-3'',4''-dihydroxycinnamoyl] arbutin (3), were isolated from the leaves of Heliciopsis lobata (Merr.) Sleum. Their structures were elucidated by variou...

journal_title：Journal of Asian natural products research

authors： He QQ,Liu MS,Jin DJ,Kong LY

更新日期：2006-06-01 00:00:00

abstract：:Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

journal_title：Journal of Asian natural products research

authors： Hua F,Shang S,Hu ZW

更新日期：2017-04-01 00:00:00