New abietane diterpenoid glucosides from underground parts of Isodon taliensis.

Abstract:

:Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 - 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts of Isodon taliensis. Their structures were elucidated based on the analyses of extensive spectroscopic data and physicochemical properties. The two new compounds were tested for their bioactivities against malaria and diabetes by β-hematin formation inhibition and α-glycosidase inhibition experiments, respectively. However, only 2 showed weak β-hematin formation inhibitory activity. [Formula: see text].

journal_name

J Asian Nat Prod Res

authors

Xiang P,Xiao CJ,Xu W,Shan H,Qiu L,Li Y,Dong X,Jiang B

doi

10.1080/10286020.2018.1518321

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

1177-1183

issue

12

eissn

1028-6020

issn

1477-2213

journal_volume

21

pub_type

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