Alkaloids with antioxidant activities from Aconitum handelianum.

Abstract:

:A new C20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C20-diterpenoid alkaloids with vicinal-triol system and benzyltetrahydroisoquinoline alkaloids exhibited significant antioxidant activities measured by three antioxidant test systems. The aconitine-type C19-diterpenoid alkaloids could serve as potential secondary antioxidants for their strong binding effects to metal ions.

journal_name

J Asian Nat Prod Res

authors

Yin TP,Cai L,Xing Y,Yu J,Li XJ,Mei RF,Ding ZT

doi

10.1080/10286020.2015.1114473

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

603-10

issue

6

eissn

1028-6020

issn

1477-2213

journal_volume

18

pub_type

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