Anti-hyperglycemic effect of 11-hydroxypalmatine, a palmatine derivative from Stephania glabra tubers.

abstract：:Tripterygium wilfordii Hook. f. is the traditional medicinal plants in China. Triptolide, wilforgine, and wilforine are the bioactive compounds in T. wilfordii. In this study, the contents of three metabolites and transcription levels of 21 genes involved in three metabolites biosynthesis in T. wilfordii were examined...

journal_title：Journal of Asian natural products research

authors： Zhang J,Huo YB,Liu Y,Feng JT,Ma ZQ,Zhu CS,Zhang X

更新日期：2017-08-01 00:00:00

abstract：:Thiazinogeldanamycin (2) was identified from Streptomyces hygroscopicus 17997 at the late stage of the fermentation. The pH was firstly proposed as an important factor in the biosynthesis of it. It was verified that 2 was produced by direct chemical reactions between geldanamycin (1, GDM) and cysteine or aminoethaneth...

journal_title：Journal of Asian natural products research

authors： Liu YF,Zhong JJ,Lin L,Liu JJ,Wang YG,He WQ,Yang ZY

更新日期：2016-08-01 00:00:00

abstract：:Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 →...

journal_title：Journal of Asian natural products research

authors： Zhang XT,Ma SW,Jiao HY,Zhang QW

更新日期：2012-01-01 00:00:00

abstract：:A series of novel tetrandrine (Tet) derivatives were synthesized through Suzuki -Miyaura reaction and evaluated for their cytotoxicity against human non-small cell lung carcinoma (NSCLC) A549 cells. Interestingly, most of derivatives showed similar cytotoxicity to Tet against NSCLC A549 cells, and particularly, compou...

journal_title：Journal of Asian natural products research

authors： Yang QH,Jiang CS,Jin T,Xu JF,Qu TL,Guo YW,Zhao ZB

更新日期：2018-11-01 00:00:00

abstract：:The chemical investigation on the fruiting bodies of Amauroderma subresinosum led to the isolation of 10 compounds including 2 new ones named amaurosubresin (1) and erythro(23,24)-5α,6α-epoxyergosta-8-ene-7-one-3β,23-diol (2). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. T...

journal_title：Journal of Asian natural products research

authors： Wang Q,Wang YG,Ma QY,Huang SZ,Kong FD,Zhou LM,Dai HF,Zhao YX

更新日期：2016-11-01 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) and their regulating enzyme soluble epoxide hydrolase (sEH) have been associated with ischemic stroke. Salvianolic acid A (SAA) is proved to display potent cerebroprotection. However, little information is available about the link between them. This study aimed to investigate whether S...

journal_title：Journal of Asian natural products research

authors： Wang SB,Pang XB,Zhao Y,Wang YH,Zhang L,Yang XY,Fang LH,Du GH

更新日期：2012-01-01 00:00:00

abstract：:Two new ent-kaurane diterpenoid dimers, fritillebinide D (1) and fritillebinide E (2), were isolated from bulbs of Fritillaria ebeiensis G.D. Yu et G.Q. Ji. Their structures have been determined to be ent-3beta-acetoxy-kauran-16beta, 17-acetal ent-3beta-acetoxy-16beta-kauran-17(R)-aldehyde (1) and ent-3beta-acetoxy-ka...

journal_title：Journal of Asian natural products research

authors： Ruan HL,Zhang YH,Wu JZ,Sun HD,Fujita T

更新日期：2002-12-01 00:00:00

abstract：:Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

journal_title：Journal of Asian natural products research

authors： Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

更新日期：2010-12-01 00:00:00

abstract：:Fasciospyrinadine (1), a novel sesquiterpene pyridine alkaloid with a previously unreported skeleton featuring a monocyclicfarnesane moiety attached to a 3-methylenepyridine residue, was isolated from the sponge Fasciospongia sp. from Weizhou Island, Guangxi Autonomous Region. The structure and the relative stereochem...

journal_title：Journal of Asian natural products research

authors： Zhao ZB,Sun JZ,Mao SC,Guo YW

更新日期：2013-01-01 00:00:00

abstract：:Three new flavonol glycosides, kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside (1), kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside-7-O-beta-D-glucopyranoside (2), and kaempferol-3-O-(6-trans-p-coumaroyl)-beta-D-glucopyranosyl-(1 --> 2)-...

journal_title：Journal of Asian natural products research

authors： Li N,Li X,Meng DL,Guo YQ,Wang JH

更新日期：2006-01-01 00:00:00

abstract：:Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...

journal_title：Journal of Asian natural products research

authors： Zheng Q,Feng Y,Xu DS,Lin X,Chen YZ

更新日期：2009-01-01 00:00:00

abstract：:Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

journal_title：Journal of Asian natural products research

authors： Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

更新日期：2013-11-01 00:00:00

abstract：:A new amide alkaloid, N-(3',4',5'-trimethoxy-cis-cinnamoyl)pyrrolidine (1), named sarmentomicine was isolated from the ethanol extract of the leaves of Malayan Piper sarmentosum, together with two known phenylpropanoids. Their structures were elucidated on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Sim KM,Mak CN,Ho LP

更新日期：2009-08-01 00:00:00

abstract：:Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

journal_title：Journal of Asian natural products research

authors： Mu LH,Li JB,Yang JZ,Zhang DM

更新日期：2007-09-01 00:00:00

abstract：:One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...

journal_title：Journal of Asian natural products research

authors： Zhang X,Liu F,Feng ZM,Jiang JS,Yang YN,Zhang PC

更新日期：2021-01-18 00:00:00

abstract：:Four new diterpenoids named 1-epi-9-hydroxydepressin (1), 1-epi-8-hydroxydepressin (2), 2,13,9-trihydroxy-labda-8(17),12(E),14-triene (3) and tagalsin I (4) were isolated from Euphorbia rapulum. The structures of these compounds were elucidated by means of various spectroscopic methods. All the isolated compounds were...

journal_title：Journal of Asian natural products research

authors： Liu XX,Shang L,Huang C,Feng XS,Li W,Sha Y,Huang J,Wang JH

更新日期：2016-09-01 00:00:00

abstract：:Two new 3,4-seco-lanostane-type triterpenes, named as 15α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1), 5α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid 3-methyl ester (2), and one new lanostane triterpene 15α-acetoxylhydroxytrametenolic acid (3) together with a known one versisponic aci...

journal_title：Journal of Asian natural products research

authors： Yin X,Li ZH,Li Y,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:Chromatographic separation of the ethyl acetate soluble part of the methanolic extract from Seriphidium stenocephalum yielded three new compounds: stenocepflavone (1), stenocepflavan (2), and stenocephol (3), together with cirsimaritin (4), 5,7,5'-trihydroxy-3',4',6-trimethoxyflavone (5), 5,6,7,5'-tetrahydroxy-4'-meth...

journal_title：Journal of Asian natural products research

authors： Shafiq N,Riaz N,Ahmed S,Ashraf M,Ejaz SA,Ahmed I,Saleem M,Touseef MI,Tareen RB,Jabbar A

更新日期：2013-01-01 00:00:00

abstract：:Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature ...

journal_title：Journal of Asian natural products research

authors： Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WD

更新日期：2011-12-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain...

journal_title：Journal of Asian natural products research

authors： Xie XL,Ye GH,Xue JJ,Su T,Tang GH,Li W,Yin S

更新日期：2020-05-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:Two new (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates (7 and 8) were synthesized and evaluated for biological activity. Compound 8 showed highly potent anticancer activity against A-549 cell line with IC50 of 2.16 ± 1.02 μM, which displayed the highest selectivity index value (SI = 14.5) in A-54...

journal_title：Journal of Asian natural products research

authors： Zi CT,Yang L,Hu Y,Zhang P,Tang H,Zhang BL,Shen XJ,Kong QH,Wang Y,Wang XJ,Sheng J

更新日期：2020-07-03 00:00:00

abstract：:Three new acetylated anthraquinone glycosides (1-3) were isolated from the seed of Cassia obtusifolia, together with one parent anthraquinone glycoside (1a). Their structures were determined on the basis of spectroscopic methods and physicochemical properties as obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1)...

journal_title：Journal of Asian natural products research

authors： Wu XH,Cai JJ,Ruan JL,Lou JS,Duan HQ,Zhang J,Cheng CR,Guo DA,Wu ZY,Zhang YW

更新日期：2011-06-01 00:00:00

abstract：:Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

journal_title：Journal of Asian natural products research

authors： Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

更新日期：2005-10-01 00:00:00

abstract：:A new pyranoxanthone, venuloxanthone (1), was isolated from the stem bark of Calophyllum venulosum, together with three other xanthones, tovopyrifolin C (2), ananixanthone (3) and caloxanthone I (4), along with two common triterpenes, friedelin (5) and lupeol (6). The structures of these compounds were identified usin...

journal_title：Journal of Asian natural products research

authors： Bin Ismail AA,Ee GC,Bin Daud S,Teh SS,Hashim NM,Awang K

更新日期：2015-01-01 00:00:00

abstract：:Two new lignan glycosides forsythiayanoside A (1) and forsythiayanoside B (2), one new stereoisomer of lignan glycoside (+)-8-hydroxyepipinoresinol-4-O-β-D-glucopyranoside (3), together with seven known compounds (4-10), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. Compounds 4 and 10 were isolate...

journal_title：Journal of Asian natural products research

authors： Yan XJ,Peng Y,Liu ZX,Wen J,Liu QB,Li LZ,Song SJ

更新日期：2014-01-01 00:00:00

abstract：:Andrographolide, a major bioactive compound isolated from Andrographis paniculata (Burm. F.) Nees, was evaluated for its effects on the hOAT1 membrane transporter. Substrate determination and inhibition of hOAT1-mediated uptake transport assay was carried out using recombinant CHO-hOAT1 cells. The results showed that ...

journal_title：Journal of Asian natural products research

authors： Chong YM,Kaur G,Tan ML

更新日期：2019-08-01 00:00:00

abstract：:Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1-2) and three known analogs (3-5) including a new natural product (5). Their structures were determined on the...

journal_title：Journal of Asian natural products research

authors： Sun ZH,Liang FL,Chen YC,Liu HX,Li HH,Zhang WM

更新日期：2016-11-01 00:00:00

abstract：:Two new apianen lactones, named as guanyeliaoine I (1) and guanyeliaoine II (2), have been isolated along with seven known compounds from Polygonum perforliatum L. (Chinese name "Guanyeliao", Berberidaceae). Their structures were deduced on the basis of spectral data and chemical methods. ...

journal_title：Journal of Asian natural products research

authors： Shen T,Jia ZJ,Zheng SZ

更新日期：2007-03-01 00:00:00