Irritant and cytotoxic coumarins from Angelica glauca Edgew roots.

abstract：:A new dimeric stilbene, named shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectros...

journal_title：Journal of Asian natural products research

authors： Zhou LX,Lin M

更新日期：2000-01-01 00:00:00

abstract：:In this paper, the structure-activity relationships of chemically modified uronic acid polymer fragments from brown algae with regard to their antioxidant effects on H2O2-damaged lymphocyte were studied. The results indicated that the most potent antioxidant activity was obtained from the sulfated polysaccharide with ...

journal_title：Journal of Asian natural products research

authors： Hu JF,Gen MY,Zhang JT,Jiang HD

更新日期：2001-01-01 00:00:00

abstract：:The chemical investigation on the fruiting bodies of Amauroderma subresinosum led to the isolation of 10 compounds including 2 new ones named amaurosubresin (1) and erythro(23,24)-5α,6α-epoxyergosta-8-ene-7-one-3β,23-diol (2). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. T...

journal_title：Journal of Asian natural products research

authors： Wang Q,Wang YG,Ma QY,Huang SZ,Kong FD,Zhou LM,Dai HF,Zhao YX

更新日期：2016-11-01 00:00:00

abstract：:Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12beta-acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by ...

journal_title：Journal of Asian natural products research

authors： Guan SH,Xia JM,Yang M,Wang XM,Liu X,Guo DA

更新日期：2008-07-01 00:00:00

abstract：:In the title study, the synthesis of the vital intermediate C-nor-aconanone (3) from 4 was completed through 11 steps, mainly including semipinacol rearrangement, formation of the imines by the treatment of 10 or 20 with NBS, the cleavage of N-C19 bonds in 11 or 21 by treatment with m-CPBA and subsequently with LTA, a...

journal_title：Journal of Asian natural products research

authors： Shen XL,Chen QH,Wang FP

更新日期：2009-01-01 00:00:00

abstract：:Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin-secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11'-methyl-oleosidyl-(7'-->6'')]-beta-D-glucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectro...

journal_title：Journal of Asian natural products research

authors： Xiao K,Song QH,Zhang SW,Xuan LJ

更新日期：2008-01-01 00:00:00

abstract：:During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

journal_title：Journal of Asian natural products research

authors： Guan YY,Li SZ,Lei PS

更新日期：2017-05-01 00:00:00

abstract：:Three new flavonol glycosides, kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside (1), kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside-7-O-beta-D-glucopyranoside (2), and kaempferol-3-O-(6-trans-p-coumaroyl)-beta-D-glucopyranosyl-(1 --> 2)-...

journal_title：Journal of Asian natural products research

authors： Li N,Li X,Meng DL,Guo YQ,Wang JH

更新日期：2006-01-01 00:00:00

abstract：:Three new sesquiterpenoids (1-3), along with four known compounds (4-7), were isolated from cultures of the fungus Conocybe siliginea. The structures of new compounds were elucidated using spectroscopic methods. The known compounds were identified by comparing their spectroscopic data with those reported in the litera...

journal_title：Journal of Asian natural products research

authors： Yang XY,Li ZH,Dong ZJ,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:A new diterpenoid, dehydrovibsanin G (1), a new lignan, (+)-9'-O-senecioyllariciresinol (2), and six known compounds (3-8) were isolated from the branches and leaves of Viburnum odoratissimum var. odoratissimum. The structures of these compounds were elucidated by analysis of spectroscopic data. Both new compounds sho...

journal_title：Journal of Asian natural products research

authors： Li FJ,Yu JH,Wang GC,Zhang H,Yue JM

更新日期：2015-05-01 00:00:00

abstract：:One kinds of glycolipid (SBI) have been isolated from the marine brown alga Sargassum hemiphyllum (Turn.) Ag. The structures of SBI have been determined as the sodium salt of 1-0-acyl-3-0-(6'-sulfo-alpha-D-quinovopyrannosyl) glycerol (acyl: tetradecanoyl, pentadecanoyl, 11-hexadecenoyl, hexadecanoyl, 10,13-octadecadie...

journal_title：Journal of Asian natural products research

authors： Cui Z,Li YS,Liu HB,Yuan D,Lu BR

更新日期：2001-01-01 00:00:00

abstract：:A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conju...

journal_title：Journal of Asian natural products research

authors： Xu P,Liu L,He W,Li Y,Liu J,Lei PS

更新日期：2009-10-01 00:00:00

abstract：:Two new anthraquinones, methyl 8-hydroxy-3-methoxy-6,7-methylenedioxy-1-methylanthraquinone-2-carboxylate (gandavensin A, 1) and methyl 8-hydroxy-3,6,7-trimethoxy-1-methylanthraquinone-2-carboxylate (gandavensin B, 2), have been isolated from the light petroleum extract of the subterranean corm of Gladiolus gandavensi...

journal_title：Journal of Asian natural products research

authors： Wang DY,Ye Q,Zhang GL,Li BG

更新日期：2003-12-01 00:00:00

abstract：:Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture o...

journal_title：Journal of Asian natural products research

authors： Tian XY,Wang YH,Yang QY,Yu SS,Fang WS

更新日期：2009-01-01 00:00:00

abstract：:Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

journal_title：Journal of Asian natural products research

authors： Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

更新日期：2010-12-01 00:00:00

abstract：:Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

journal_title：Journal of Asian natural products research

authors： Li J,Wang XL,Wang AP,Xu SF,Jin HT

更新日期：2017-04-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:Pharmacochemistry and integrated pharmacokinetics of six alkaloids (groenlandicine, berberine, palmatine, epiberberine, jatrorrhizine, and columbamine) after oral administration of Huang-Lian-Jie-Du-Tang (HLJDT) decoction were investigated in this paper. The method of plasma pharmacochemistry was applied to predict th...

journal_title：Journal of Asian natural products research

authors： Ma ZT,Yang XW,Zhang Y,Liu JX

更新日期：2014-01-01 00:00:00

abstract：:An ongoing phytochemical investigation of the rhizomes of Atractylodes lancea resulted in the isolation of four new C10-type polyacetylene glycosides (1-4). Their structures were elucidated on the basis of extensive spectroscopic data (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of compounds 2-4 w...

journal_title：Journal of Asian natural products research

authors： Xu K,Feng ZM,Yang YN,Jiang JS,Zhang PC

更新日期：2017-02-01 00:00:00

abstract：:Four new C19-diterpenoid alkaloids, hemaconitines A-D (1-4), were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated as 19R-hydroxyl-secoyunnaconitine (1), (3R)-hydroxyl-liwaconitine (2), 14-anisoyl-leucanthumsine E (3), and 19R -acetonyl-8-O-methyltalatisamine (4) by ext...

journal_title：Journal of Asian natural products research

authors： He D,Liu WY,Xiong J,Xu JJ,Shen Y

更新日期：2019-09-01 00:00:00

abstract：:Two new neolignan glucosides named (7S, 8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxyl-7'-oxo-8-4'-oxyneolignan-4-O-β-D-glucopyranoside and (7'S, 8'R, 8S)-4,4',9'-trihydroxy-3,3'-dimethoxy-7',9-epoxylignan-7-oxo-4-O-β-D-glucopyranosyl-4'-O-β-D-glucopyranoside, together with two small molecular peptides named 3-benzyl-6-(1-...

journal_title：Journal of Asian natural products research

authors： Yang YN,Zhang F,Feng ZM,Jiang JS,Zhang PC

更新日期：2012-01-01 00:00:00

abstract：:Thiazinogeldanamycin (2) was identified from Streptomyces hygroscopicus 17997 at the late stage of the fermentation. The pH was firstly proposed as an important factor in the biosynthesis of it. It was verified that 2 was produced by direct chemical reactions between geldanamycin (1, GDM) and cysteine or aminoethaneth...

journal_title：Journal of Asian natural products research

authors： Liu YF,Zhong JJ,Lin L,Liu JJ,Wang YG,He WQ,Yang ZY

更新日期：2016-08-01 00:00:00

abstract：:Two new drimane sesquiterpenoids, 11,12-dihydroxy-15-drimeneoic acid (1) and 3α,11,15-trihydroxydrimene (2), were isolated from cultures of the basidiomycete Agaricus arvensis, together with one known compound 3β,11,12-trihydroxydrimene (3). Their structures were established by means of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Ding JH,Li ZH,Dong ZJ,Feng T,Zhang HB,Liu JK

更新日期：2013-01-01 00:00:00

abstract：:A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

journal_title：Journal of Asian natural products research

authors： Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

更新日期：2018-05-01 00:00:00

abstract：:A new pyranoxanthone, venuloxanthone (1), was isolated from the stem bark of Calophyllum venulosum, together with three other xanthones, tovopyrifolin C (2), ananixanthone (3) and caloxanthone I (4), along with two common triterpenes, friedelin (5) and lupeol (6). The structures of these compounds were identified usin...

journal_title：Journal of Asian natural products research

authors： Bin Ismail AA,Ee GC,Bin Daud S,Teh SS,Hashim NM,Awang K

更新日期：2015-01-01 00:00:00

abstract：:A total of 15 novel-substituted 3-(benzylsulfanyl)-1H-1,2,4-triazol-5-ylamine and 10 novel-substituted 3-benzylmercapto-1,2,4-triazol derivatives were synthesized based on the natural product phenazine-1-carboxylic acid (PCA). Their structures were confirmed by 1H-NMR, 13C-NMR, HRMS, and X-ray. Most substituted 3-benz...

journal_title：Journal of Asian natural products research

authors： Li XJ,Zhang W,Zhao CN,Wu QL,Li JK,Xu ZH

更新日期：2020-05-07 00:00:00

abstract：:Three new iridoids, named artselaenin I, II and III, were isolated from the whole plants of Pedicularis artselaeri, along with 11 known compounds, 8-epiloganic acid, 7-deoxy-8-epiloganic acid, plantarenaloside, mussaenoside, lariciresinol-4-O-beta-D-glucoside, lariciresinol-4'-O-beta-D-glucoside, alaschaniosideA, cirt...

journal_title：Journal of Asian natural products research

authors： Su BN,Zhai JJ,Jia ZJ

更新日期：1998-01-01 00:00:00

abstract：:Three new polyoxypregnane glycosides, tenacigenosides F-H (1-3), were isolated from the stems of Marsdenia tenacissima. The structures of these new compounds were elucidated from 1D and 2D NMR spectra, as well as from HR-MS and acid hydrolysis. ...

journal_title：Journal of Asian natural products research

authors： Wang XL,Peng SL,Ding LS

更新日期：2010-08-01 00:00:00

abstract：:Two new constituents with a novel basic skeleton were isolated from Erigeron breviscapus. On the basis of chemical and spectroscopic evidences, the structures of the new compounds were elucidated as 1R,3R-dihydroxy-4S,5R-dicaffeoyloxy cyclohexane carboxylic acid methyl ester (V), 1,4-dihydroxy-3R,5R-dicaffeoyloxy cycl...

journal_title：Journal of Asian natural products research

authors： Zhang WD,Tam HT,Chen WS,Kong DY,Li HT,Wang YH,Fouraste I

更新日期：2000-01-01 00:00:00