Abstract:
:During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell lines and compound 6 (IC50 = 2.40-9.05 μM) showed potential antitumor activities against HELA, BGC-823, KB, A549, HCT-8 cell lines.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Guan YY,Li SZ,Lei PSdoi
10.1080/10286020.2016.1228633subject
Has Abstractpub_date
2017-05-01 00:00:00pages
481-488issue
5eissn
1028-6020issn
1477-2213journal_volume
19pub_type
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