Abstract:
:Four spiroalkaloids, including a new compound shensongine A (1), were isolated from the anti-arrhythmic TCM formula Shensong Yangxin capsule. Their structures were determined on the basis of spectroscopic analysis. Compounds 1 and 3 displayed cardiovascular activities by shortened APD in rat myocardial cells. These compounds were possibly generated from precursors in different composed herbal medicines during the processing of the TCM formula.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Ding B,Dai Y,Hou YL,Yao XSdoi
10.1080/10286020.2015.1047354subject
Has Abstractpub_date
2015-05-01 00:00:00pages
559-66issue
5eissn
1028-6020issn
1477-2213journal_volume
17pub_type
杂志文章abstract::Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed mod...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2016.1234458
更新日期:2017-05-01 00:00:00
abstract::A new sesquiterpene cacaroborin (1) was isolated from the roots of Cacalia roborowskii, together with three known ones, cinalbicol (2), isopetasin (3), and 3alpha-angeloyloxylactone (4). The structure of compound 1 was elucidated as 1beta,10alpha-dihydroxy-8alpha-methoxyeremophil-7(11)-en-8beta,12-olide on the basis o...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020903264093
更新日期:2009-11-01 00:00:00
abstract::Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020902727363
更新日期:2009-01-01 00:00:00
abstract::A new diterpenoid, dehydrovibsanin G (1), a new lignan, (+)-9'-O-senecioyllariciresinol (2), and six known compounds (3-8) were isolated from the branches and leaves of Viburnum odoratissimum var. odoratissimum. The structures of these compounds were elucidated by analysis of spectroscopic data. Both new compounds sho...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2015.1041934
更新日期:2015-05-01 00:00:00
abstract::Three new sesquiterpenoids (1-3), along with four known compounds (4-7), were isolated from cultures of the fungus Conocybe siliginea. The structures of new compounds were elucidated using spectroscopic methods. The known compounds were identified by comparing their spectroscopic data with those reported in the litera...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2014.939072
更新日期:2015-01-01 00:00:00
abstract::Phytochemical investigations of the whole plant of Stachys parviflora (Lamiaceae) resulted in the isolation of two new phenethyl alcohol glycosides. The structures of the new compounds named parviflorosides A and B were established as 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-E-caffeoyl-bet...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020500478708
更新日期:2006-01-01 00:00:00
abstract::Camellia oleifera is expected to provide alternative aglycone to synthesize some saponins similar to that from Schima superba with inhibitory activity against Magnaporthe oryzae. Eight theasapogenol galactosides were synthesized via protection of adjacent hydroxyl groups by a benzylidene for regioselective glycosylati...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1325877
更新日期:2018-02-01 00:00:00
abstract::One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2021.1873298
更新日期:2021-01-18 00:00:00
abstract::A phytochemical investigation on the whole plant of Aconitum tanguticum (Ranunculaceae) resulted in the isolation and characterization of two new phenylpropanoid glycosides (1 and 2). Their structures were elucidated as 4-hydroxyphenethoxy-8-O-β-d-[6-O-(4-O-β-d-glucopyranosyl)-sinapoyl]-glucopyranoside (1) and 3,4-dim...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2014.904292
更新日期:2014-01-01 00:00:00
abstract::The Amaranthaceae plant, Pfaffia glomerata, which is so-called as Brazil ginseng, is widely distributed in South American countries. Three new noroleanane-type triterpenes and four known oleanane-type triterpenes were isolated from the roots of P. glomerata. Their structures were determined by spectroscopic methods in...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1343820
更新日期:2018-05-01 00:00:00
abstract::A new phenolic glycoside, 6'-[(E)-2''-hydroxymethyl, 2''-butenoyl] arbutin (1), and two known phenolic glycosides, 6'-[(E)-4''-hydroxycinnamoyl] arbutin (2) and 6'-[(E)-3'',4''-dihydroxycinnamoyl] arbutin (3), were isolated from the leaves of Heliciopsis lobata (Merr.) Sleum. Their structures were elucidated by variou...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020500172251
更新日期:2006-06-01 00:00:00
abstract::Two new homoisoflavonoids, ( ± )-5,7-dihydroxy-8-methyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (1) and ( ± )-5,7-dihydroxy-6,8-dimethyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (2), along with two known homoisoflavonoids, 5,7-dihydroxy-6-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (3) and disporopsin (4), were isola...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2014.930444
更新日期:2014-01-01 00:00:00
abstract::A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2012.743529
更新日期:2013-01-01 00:00:00
abstract::Two new lignans named spicatolignan A (1) and spicatolignan B (2) have been isolated from the whole herbs of Mentha spicata L. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020500384641
更新日期:2007-04-01 00:00:00
abstract::A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conju...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020903176461
更新日期:2009-10-01 00:00:00
abstract::Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1302940
更新日期:2017-04-01 00:00:00
abstract::Two new meroterpenes, guignardone D (1) and guignardone E (2), were isolated from endophytic fungus A1 of Scyphiphora hydrophyllacea Gaertn. F. Their structures were established based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY, HMBC, and ROESY). ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2012.693078
更新日期:2012-01-01 00:00:00
abstract::Two new glycosides named as ternatoside A (1) and ternatoside B (2), with four known constituents sternbin (3), methylparaben (4), 4-O-D-glucopyranosyl-p-coumaric acid (5) and linocaffein (6) were isolated from the roots of Ranunculus ternatus, The structures of new compounds were determined by 1D and 2D NMR, MS techn...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020500385663
更新日期:2006-01-01 00:00:00
abstract::Two new anthraquinones, methyl 8-hydroxy-3-methoxy-6,7-methylenedioxy-1-methylanthraquinone-2-carboxylate (gandavensin A, 1) and methyl 8-hydroxy-3,6,7-trimethoxy-1-methylanthraquinone-2-carboxylate (gandavensin B, 2), have been isolated from the light petroleum extract of the subterranean corm of Gladiolus gandavensi...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/1028602031000111950
更新日期:2003-12-01 00:00:00
abstract::Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2010.489039
更新日期:2010-07-01 00:00:00
abstract::Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataoside...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020701604839
更新日期:2008-03-01 00:00:00
abstract::Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020802031080
更新日期:2008-07-01 00:00:00
abstract::A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, 1H and 13C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020500176922
更新日期:2006-09-01 00:00:00
abstract::Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture o...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020802413239
更新日期:2009-01-01 00:00:00
abstract::A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1670169
更新日期:2020-05-01 00:00:00
abstract::Three new xanthones, 1,3-dihydroxy-2,5,6,7-tetramethoxyxanthone (1), 3-hydroxy-1,2,5,6,7-pentamethoxyxanthone (2), and 3,8-dihydroxy-1,2,6-trimethoxyxanthone (3), together with two known compounds were isolated from the roots of Polygala japonica Houtt. Their structures were determined on the basis of spectroscopic da...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020902835547
更新日期:2009-01-01 00:00:00
abstract::Our goals were to examine the dual-directional regulation effects of resveratrol (1) in vitro by using MCF-7 cells (estradiol receptor-positive cells), study its mechanism of action, and give a systematical analysis of the regulatory networks of each related factor. An MTT test and growth curve showed that the prolife...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020902772096
更新日期:2009-01-01 00:00:00
abstract::A palmatine derivative, named 11-hydroxypalmatine (4), has been isolated from the tubers of Stephania glabra, together with three known alkaloids, palmatine (1), dehydrocorydalmine (2), and stepharanine (3). The structures of the compounds were elucidated by means of spectroscopic analysis including 2D NMR experiments...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020903117325
更新日期:2010-02-01 00:00:00
abstract::During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2016.1228633
更新日期:2017-05-01 00:00:00
abstract::A new phenanthraquinone, named bauhinione (1), has been isolated from Bauhinia variegata L., and its structure has been elucidated as 2,7-dimethoxy-3-methyl-9,10-dihydrophenanthrene-1,4-dione on the basis of spectroscopic analysis. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020410001721140
更新日期:2005-12-01 00:00:00