Annonaceous acetogenins of the seeds from Annona muricata.

abstract：:Microbial transformation of oleanolic acid (1) was carried out. Six transformed products (2-7) from 1 by Alternaria longipes and three transformed products (8-10) from 1 by Penicillium adametzi were isolated. Their structures were elucidated as 2α,3α,19α-trihydroxy-ursolic acid-28-O-β-d-glucopyranoside (2), 2α,3β,19α-...

journal_title：Journal of Asian natural products research

authors： Liu DL,Liu Y,Qiu F,Gao Y,Zhang JZ

更新日期：2011-02-01 00:00:00

abstract：:Two new xanthone O-glycosides, polyhongkongenosides A (1) and B (2), together with four known xanthone glycosides, were isolated from the herbs of Polygala hongkongensis Hemsl. Their structures were elucidated on the basis of UV, IR, NMR, and MS spectral data. The antioxidant in vitro activities of 1-6 were determined...

journal_title：Journal of Asian natural products research

authors： Wu JF,Chen SB,Gao JC,Song HL,Wu LJ,Chen SL,Tu PF

更新日期：2008-07-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:Two new constituents with a novel basic skeleton were isolated from Erigeron breviscapus. On the basis of chemical and spectroscopic evidences, the structures of the new compounds were elucidated as 1R,3R-dihydroxy-4S,5R-dicaffeoyloxy cyclohexane carboxylic acid methyl ester (V), 1,4-dihydroxy-3R,5R-dicaffeoyloxy cycl...

journal_title：Journal of Asian natural products research

authors： Zhang WD,Tam HT,Chen WS,Kong DY,Li HT,Wang YH,Fouraste I

更新日期：2000-01-01 00:00:00

abstract：:A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

journal_title：Journal of Asian natural products research

authors： Kong LY,Zhi F

更新日期：2003-09-01 00:00:00

abstract：:Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

journal_title：Journal of Asian natural products research

authors： Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

更新日期：2009-06-01 00:00:00

abstract：:Three new polyoxypregnane glycosides, tenacigenosides F-H (1-3), were isolated from the stems of Marsdenia tenacissima. The structures of these new compounds were elucidated from 1D and 2D NMR spectra, as well as from HR-MS and acid hydrolysis. ...

journal_title：Journal of Asian natural products research

authors： Wang XL,Peng SL,Ding LS

更新日期：2010-08-01 00:00:00

abstract：:Two new lignans, 9-salicyl-(+)-isolariciresinol (1) and gaultheroside G (2), together with seven known compounds, were isolated from the ethanolic extract of the whole plant of Gaultheria yunnanensis. Their structures were determined by extensive NMR and MS analyses. Gaultheroside G (2) was found to have an unusual et...

journal_title：Journal of Asian natural products research

authors： Gao YP,Shen YH,Xu XK,Tian JM,Zeng HW,Lin S,Liu CM,Zhang WD

更新日期：2014-01-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%. ...

journal_title：Journal of Asian natural products research

authors： Zhang JX,Li ZY,Wang YC,Ma WB,Hou M,Cao SH,Tang KH,Dong HB

更新日期：2017-09-01 00:00:00

abstract：:During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

journal_title：Journal of Asian natural products research

authors： Guan YY,Li SZ,Lei PS

更新日期：2017-05-01 00:00:00

abstract：:A new minor sesquiterpene lactone glucoside, ixerin ZA (1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-[6'-(p-metheoxyphenylacetyl)]-beta-glucopyranoside on the basis of sp...

journal_title：Journal of Asian natural products research

authors： He WF,Xu BB,Pan JC,Lu JC,Song SJ,Xu SX

更新日期：2006-09-01 00:00:00

abstract：:Two new glycosides named as ternatoside A (1) and ternatoside B (2), with four known constituents sternbin (3), methylparaben (4), 4-O-D-glucopyranosyl-p-coumaric acid (5) and linocaffein (6) were isolated from the roots of Ranunculus ternatus, The structures of new compounds were determined by 1D and 2D NMR, MS techn...

journal_title：Journal of Asian natural products research

authors： Tian JK,Sun F,Cheng YY

更新日期：2006-01-01 00:00:00

abstract：:(-)-Incrustoporin (1) has been synthesized using aldol condensation of ethyl p-tolyl-acetate (2) and (2R)-benzoyloxy-butanal (3), followed by acid-catalyzed deprotection of the benzoyl group, lactone ring-closure, and elimination of the beta-OH in a one-pot manner. The aldehyde 3 was prepared from the commercially ava...

journal_title：Journal of Asian natural products research

authors： Yu Q,Liu JF,Wu YL

更新日期：1999-01-01 00:00:00

abstract：:A new periplogenin cardenolide, periplogulcoside (1), together with three known cardenolides, was isolated from the seeds of Antiaris toxicaria. The structure of the new compound was characterized as periplogenin-3-O-β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranoside (1) by spectroscopic methods including 1D and 2D NMR, H...

journal_title：Journal of Asian natural products research

authors： Wu XL,Wu YL,Li HG,Liu HT,Fu XY,Cui RQ,Wang JH,Liu C,Chen J

更新日期：2014-01-01 00:00:00

abstract：:An ongoing phytochemical investigation of the rhizomes of Atractylodes lancea resulted in the isolation of four new C10-type polyacetylene glycosides (1-4). Their structures were elucidated on the basis of extensive spectroscopic data (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of compounds 2-4 w...

journal_title：Journal of Asian natural products research

authors： Xu K,Feng ZM,Yang YN,Jiang JS,Zhang PC

更新日期：2017-02-01 00:00:00

abstract：:The chemical investigation on the fruiting bodies of Amauroderma subresinosum led to the isolation of 10 compounds including 2 new ones named amaurosubresin (1) and erythro(23,24)-5α,6α-epoxyergosta-8-ene-7-one-3β,23-diol (2). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. T...

journal_title：Journal of Asian natural products research

authors： Wang Q,Wang YG,Ma QY,Huang SZ,Kong FD,Zhou LM,Dai HF,Zhao YX

更新日期：2016-11-01 00:00:00

abstract：:Andrographolide (1), a diterpenoid lactone isolated from a traditional herb (Andrographis paniculata), is known to possess potent anti-inflammatory activity. In this study, we investigated the anti-tumor effect of 1 on various cancer cell lines in vitro. It induced apoptosis of prostate cancer (PC-3) cells (the most s...

journal_title：Journal of Asian natural products research

authors： Zhao F,He EQ,Wang L,Liu K

更新日期：2008-05-01 00:00:00

abstract：:A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syn...

journal_title：Journal of Asian natural products research

authors： Liu J,Song JG,Su JC,Huang XJ,Ye WC,Wang Y

更新日期：2018-01-01 00:00:00

abstract：:Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature ...

journal_title：Journal of Asian natural products research

authors： Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WD

更新日期：2011-12-01 00:00:00

abstract：:Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...

journal_title：Journal of Asian natural products research

authors： Zhao MY,Yang XW

更新日期：2008-07-01 00:00:00

abstract：:A new selaginellin derivative, selaginellin M (1), together with one known compound, selaginellin E (2), was isolated from Selaginella pulvinata. The structure of the new compound was elucidated and named as (R,S)-4-((4'-hydroxy-4-((2-hydroxyethoxy)methyl))-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)me...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Liu GR,Long HP,Li J,Li FS,Zou ZX,Kuang JW,Xie X,Tan GS

更新日期：2011-10-01 00:00:00

abstract：:A new phenyldihydronaphthalene-type lignan, vitexdoin F (1), along with 22 known lignan derivatives (2-23) was isolated from the seeds of Vitex negundo var. cannabifolia. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analyses. The antioxidant activities of these lignans were evaluated ...

journal_title：Journal of Asian natural products research

authors： Lou ZH,Li HM,Gao LH,Li RT

更新日期：2014-01-01 00:00:00

abstract：:Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

journal_title：Journal of Asian natural products research

authors： Hua F,Shang S,Hu ZW

更新日期：2017-04-01 00:00:00

abstract：:A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

journal_title：Journal of Asian natural products research

authors： Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

更新日期：2009-01-01 00:00:00

abstract：:A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C ...

journal_title：Journal of Asian natural products research

authors： Yang DL,Mei WL,Zeng YB,Guo ZK,Wei DJ,Liu SB,Wang QH,Dai HF

更新日期：2013-01-01 00:00:00

abstract：:One novel ursolic acid derivative sabiracin 1 (11,25-epoxy-3β-hydroxy-urs-12-en-28-oic acid) was isolated from the leaves of Carissa carandas, together with five known compounds para hydroxy benzaldehyde (2), ursolic acid (3), carissin (4), 22α-hydroxyursolic acid (5) and β-sitosterol-3-O-β-D-glucopyranoside (6). Comp...

journal_title：Journal of Asian natural products research

authors： Bano Z,Begum S,Ali SS,Kiran Z,Siddiqui BS,Khawaja S,Ahmed A

更新日期：2020-07-10 00:00:00

abstract：:One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

journal_title：Journal of Asian natural products research

authors： Li J,Wang J,Jiang CS,Li G,Guo YW

更新日期：2014-01-01 00:00:00

abstract：:Suberoylanilide hydroxamic acid (1), as well as other histone deacetylase (HDAC) inhibitors, are promising, targeted anticancer agents. Curcumin (2), a possible antitumor agent, exhibits a HDAC inhibiting effect but with a different mechanism, and was proposed to synergize with other drugs, including HDAC inhibitors. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Lu N,Yan Z,Wang N

更新日期：2010-05-01 00:00:00

abstract：:Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

journal_title：Journal of Asian natural products research

authors： Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

更新日期：2013-11-01 00:00:00