Annonaceous acetogenins of the seeds from Annona muricata.

Abstract:

:Muricatenol (1) is a new C37 non-THF ring acetogenin with four hydroxyls and one isolated double bond in the long aliphatic chain. 2,4-cis-Gigantetrocinone (2) and 2,4-trans-gigantetrocinone (3) have been isolated as their acetates by preparative TLC. 2,4-trans-Isoannonacin-10-one (4) and 2,4-trans-isoannonacin (5) have been isolated as only 2,4-trans-form for the first time (no cis-form). Also four known acetogenins, gigantetrocin-A (6), gigantetrocin-B (7), annomontacin (8), gigantetronenin (9) and a mixture of N-fatty acyl tryptamines have been isolated (10). Their structures have been established on the basis of spectral analyses. The CHCl3 fraction of the seeds showed strong antitumor activities.

journal_name

J Asian Nat Prod Res

authors

Li DY,Yu JG,Zhu JX,Yu DL,Luo XZ,Sun L,Yang SL

doi

10.1080/10286020108040366

keywords:

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

267-76

issue

4

eissn

1028-6020

issn

1477-2213

journal_volume

3

pub_type

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