A new periplogenin cardenolide from the seeds of Antiaris toxicaria.

Abstract:

:A new periplogenin cardenolide, periplogulcoside (1), together with three known cardenolides, was isolated from the seeds of Antiaris toxicaria. The structure of the new compound was characterized as periplogenin-3-O-β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranoside (1) by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectrometry, and the known compounds were identified by comparison of their NMR and HR-TOF-MS data with those reported in the literature. Compound 1 showed significant cytotoxicity against Hela and HepG-2 cell lines.

journal_name

J Asian Nat Prod Res

authors

Wu XL,Wu YL,Li HG,Liu HT,Fu XY,Cui RQ,Wang JH,Liu C,Chen J

doi

10.1080/10286020.2014.885506

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

418-21

issue

4

eissn

1028-6020

issn

1477-2213

journal_volume

16

pub_type

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