Synthesis of chrysin derivatives and screening of antitumor activity.

abstract：:Two new neolignan glucosides named (7S, 8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxyl-7'-oxo-8-4'-oxyneolignan-4-O-β-D-glucopyranoside and (7'S, 8'R, 8S)-4,4',9'-trihydroxy-3,3'-dimethoxy-7',9-epoxylignan-7-oxo-4-O-β-D-glucopyranosyl-4'-O-β-D-glucopyranoside, together with two small molecular peptides named 3-benzyl-6-(1-...

journal_title：Journal of Asian natural products research

authors： Yang YN,Zhang F,Feng ZM,Jiang JS,Zhang PC

更新日期：2012-01-01 00:00:00

abstract：:Resveratrol (3,4',5-trihydroxy-trans-silbene), a natural phytoalexin found in grapes and other food products, has promising anti-inflammatory and anticancer effects. To observe the modulation of interleukin-8 (IL-8) production in human monocytic cells by resveratrol and explore its mechanism at the gene transcription ...

journal_title：Journal of Asian natural products research

authors： Shen F,Chen SJ,Dong XJ,Zhong H,Li YT,Cheng GF

更新日期：2003-06-01 00:00:00

abstract：:Irritant and cytotoxic potentiality of six coumarins, isolated for the first time from the roots of Angelica glauca identified as 5,6,7-trimethoxycoumarin, 6-methoxy-7,8-methylenedioxycoumarin, bergapten, decursinol angelate, decursin, and nodakenetin, were investigated. The irritant potential was explored by open mou...

journal_title：Journal of Asian natural products research

authors： Saeed MA,Sabir AW

更新日期：2008-01-01 00:00:00

abstract：:Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

journal_title：Journal of Asian natural products research

authors： Hua F,Shang S,Hu ZW

更新日期：2017-04-01 00:00:00

abstract：:Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoside (1) and 4-beta-D-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranosi...

journal_title：Journal of Asian natural products research

authors： Li FS,Dou DQ,Xu L,Chi XF,Kang TG,Kuang HX

更新日期：2009-07-01 00:00:00

abstract：:Two new stemoninine-type alkaloids, stemoninine A (1) and B (2), along with two known Stemona alkaloids, bisdehydrostemoninine (3) and bisdehydrostemoninine A (4), were isolated from the roots of Stemona sessilifolia, and their structures and relative configurations were determined on the basis of spectrometric data a...

journal_title：Journal of Asian natural products research

authors： Wang P,Liu AL,Li ZH,Du GH,Qin HL

更新日期：2008-03-01 00:00:00

abstract：:Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Qi Y,Zhao DK,Zi SH,Zhang LM,Guo CX,Li GQ,Xun JJ,Shen Y

更新日期：2016-01-01 00:00:00

abstract：:A new natural coumarin, angepubebisin (1), and a new furan, angepubefurin (2), together with the five known compounds, umbelliferone, angelol B (3), ulopterol (4), peucedanol (5), and scopoletin, were isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The structures of angepubebisin (1) an...

journal_title：Journal of Asian natural products research

authors： Yang XW,Zhang CY,Zhang BG,Lu Y,Luan JW,Zheng QT

更新日期：2009-08-01 00:00:00

abstract：:A new phenyldihydronaphthalene-type lignan, vitexdoin F (1), along with 22 known lignan derivatives (2-23) was isolated from the seeds of Vitex negundo var. cannabifolia. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analyses. The antioxidant activities of these lignans were evaluated ...

journal_title：Journal of Asian natural products research

authors： Lou ZH,Li HM,Gao LH,Li RT

更新日期：2014-01-01 00:00:00

abstract：:Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...

journal_title：Journal of Asian natural products research

authors： Baloch IB,Baloch MK

更新日期：2010-07-01 00:00:00

abstract：:In this letter, (R)-muscone and (S)-muscone were prepared by optical resolution of dl-muscone using N,N'-dibenzyl-l-tartaramide or N,N'-dibenzyl-d-tartaramide, according to the method reported by Kunihiko Takabe. But we separated the diastereomers using EtOH instead of MeOH in the recrystallization step to get the goa...

journal_title：Journal of Asian natural products research

authors： Meng Y,Xiao Q,Bai JY,Xiao X,Zhang S,Zhu XY,Cheng GF,Yin DL

更新日期：2014-12-01 00:00:00

abstract：:A new sterol, stigmast-5-ene-3beta,17alpha-diol (1), together with six known compounds, stigmast-5-ene-3beta-yl formate (2), stigmast-5-ene-3beta,7alpha-diol (3), stigmast-5-ene-7alpha-methoxy-3beta-ol (4), stigmast-5-ene-3-one (5), 3beta-sitostanol (6), and 3beta-sitosterol (7), was isolated from the fruits of Syzygi...

journal_title：Journal of Asian natural products research

authors： Chumkaew P,Kato S,Chantrapromma K

更新日期：2010-05-01 00:00:00

abstract：:Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

journal_title：Journal of Asian natural products research

authors： Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

更新日期：2005-10-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:Seven new C14-polyacetylene glucosides codonopilodiynosides A-G (1-7) were isolated from an aqueous extract of the Codonopsis pilosula roots. Their structures were determined by spectroscopic and chemical methods as (-)-(5S,6E,12E)-tetradeca-6,12-dien-8,10-diyn-1,5,14-triol 5-O-β-D-glucopyranoside (1), (-)-(5S,6E,12E)...

journal_title：Journal of Asian natural products research

authors： Jiang YP,Liu YF,Guo QL,Jiang ZB,Xu CB,Zhu CG,Yang YC,Lin S,Shi JG

更新日期：2015-01-01 00:00:00

abstract：:Fasciospyrinadine (1), a novel sesquiterpene pyridine alkaloid with a previously unreported skeleton featuring a monocyclicfarnesane moiety attached to a 3-methylenepyridine residue, was isolated from the sponge Fasciospongia sp. from Weizhou Island, Guangxi Autonomous Region. The structure and the relative stereochem...

journal_title：Journal of Asian natural products research

authors： Zhao ZB,Sun JZ,Mao SC,Guo YW

更新日期：2013-01-01 00:00:00

abstract：:Pseudolaric acid-B (PLAB), a diterpene acid, was isolated from the root and trunk barks of Pseudolarix kaempferi. It showed antifungal and anti-fertility effects as well as cytotoxic activities in previous studies. The present study investigates cytotoxic activity on cultured human cancer cells, inhibition on the grow...

journal_title：Journal of Asian natural products research

authors： Liu B,Chen H,Lei ZY,Yu PF,Xiong B

更新日期：2006-04-01 00:00:00

abstract：:A new phenolic glycoside, 6'-[(E)-2''-hydroxymethyl, 2''-butenoyl] arbutin (1), and two known phenolic glycosides, 6'-[(E)-4''-hydroxycinnamoyl] arbutin (2) and 6'-[(E)-3'',4''-dihydroxycinnamoyl] arbutin (3), were isolated from the leaves of Heliciopsis lobata (Merr.) Sleum. Their structures were elucidated by variou...

journal_title：Journal of Asian natural products research

authors： He QQ,Liu MS,Jin DJ,Kong LY

更新日期：2006-06-01 00:00:00

abstract：:A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

journal_title：Journal of Asian natural products research

authors： Kong LY,Zhi F

更新日期：2003-09-01 00:00:00

abstract：:A new amide alkaloid, N-(3',4',5'-trimethoxy-cis-cinnamoyl)pyrrolidine (1), named sarmentomicine was isolated from the ethanol extract of the leaves of Malayan Piper sarmentosum, together with two known phenylpropanoids. Their structures were elucidated on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Sim KM,Mak CN,Ho LP

更新日期：2009-08-01 00:00:00

abstract：:Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

journal_title：Journal of Asian natural products research

authors： Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

更新日期：2010-10-01 00:00:00

abstract：:Dehydrozingerone analogs and related compounds were screened as potential antitumor promoters by using the in vitro short-term 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced Epstein-Barr virus early antigen activation assay. Among the 40 synthesized compounds, the prenylated analogs 16 and 34-36 showed the most si...

journal_title：Journal of Asian natural products research

authors： Tatsuzaki J,Nakagawa-Goto K,Tokuda H,Lee KH

更新日期：2010-03-01 00:00:00

abstract：:Two new monoterpenoid glycosides, α-(E)-acaridiol 8-O-β-d-glucopyranoside (1) and α-(E)-acaridiol 9-O-β-d-glucopyranoside (2), as well as a new thiophen, 2-acetyl-3-hydroxy-5-(prop-1-ynyl)thiophen 3-O-β-d-glucopyranoside (3), were isolated from the roots of Eupatorium chinense. Their structures were determined on the ...

journal_title：Journal of Asian natural products research

authors： Wang WJ,Wang Y,Zhang QW,Zhang XQ,Yang TT,Dai Y,Wang L,Zhang LH,Ye WC

更新日期：2011-09-01 00:00:00

abstract：:A new triterpene glycoside mutongsaponin F (1), together with five known saponins and two known lipids, was isolated from the 70% ethanol extract of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd. Their structures were elucidated on the basis of the spectroscopic analysis and physicochemica...

journal_title：Journal of Asian natural products research

authors： Gao HM,Wang ZM,Wang WH

更新日期：2009-12-01 00:00:00

abstract：:Four types of piscidinol A derivatives were synthesized and evaluated their ability to inhibit HIV-1 protease to understand their structure-activity relationships. Of these tirucallane-type triterpene derivatives, an A-seco derivative (1b) moderately inhibited human immunodeficiency virus (HIV) protease (IC50 38.2 μM)...

journal_title：Journal of Asian natural products research

authors： Wei Y,Ma CM,Jiang TB,Du J,Zhou X,Liu GQ,Hattori M

更新日期：2015-01-01 00:00:00

abstract：:Barlericin, the new neolignan diglycoside, has been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with dehydrodiconiferyl alcohol 12-O-beta-D-glucopyranoside (2), reported for the first time from the genus Barleria. Their structures have been assigned on the basis of spectral studies. ...

journal_title：Journal of Asian natural products research

authors： Karim A,Noor AT,Malik A

更新日期：2010-08-01 00:00:00

abstract：:A novel oxybis cresol compound named verticilatin (1), together with two known compounds, 5-methylresorcinol (2) and 2,4-dihydroxy-3,6-dimethylbenzaldehyde (3), was isolated from cultures of the insect pathogenic fungi Paecilomyces verticillatus. The structures of compounds were determined by extensive spectroscopic a...

journal_title：Journal of Asian natural products research

authors： Wei PY,Li L,Yang CG,Luo DQ,Zheng ZH,Lu XH,Shi BZ

更新日期：2014-12-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

journal_title：Journal of Asian natural products research

authors： Li J,Wang J,Jiang CS,Li G,Guo YW

更新日期：2014-01-01 00:00:00

abstract：:A new dimeric stilbene, named shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectros...

journal_title：Journal of Asian natural products research

authors： Zhou LX,Lin M

更新日期：2000-01-01 00:00:00