Total synthesis of (-)-incrustoporin.

Abstract:

:(-)-Incrustoporin (1) has been synthesized using aldol condensation of ethyl p-tolyl-acetate (2) and (2R)-benzoyloxy-butanal (3), followed by acid-catalyzed deprotection of the benzoyl group, lactone ring-closure, and elimination of the beta-OH in a one-pot manner. The aldehyde 3 was prepared from the commercially available D-mannitol by a two-directional strategy.

journal_name

J Asian Nat Prod Res

authors

Yu Q,Liu JF,Wu YL

doi

10.1080/10286029908039863

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

183-8

issue

3

eissn

1028-6020

issn

1477-2213

journal_volume

1

pub_type

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