Synthesis of piscidinol A derivatives and their ability to inhibit HIV-1 protease.

abstract：:Two new cycloartanes, named dolichandrone A (1) and dolichandrone B (2), as well as two new iridoids, named [6-O-[(E)-4-methoxycinnamoyl]-1β-hydroxy-dihydrocatalpolgenin (3) and 6-O-[(E)-4-methoxycinnamoyl]-1α-hydroxy-dihydrocatalpolgenin (4), together with four known iridoids (5-8), were isolated from the leaves and ...

journal_title：Journal of Asian natural products research

authors： Nguyen VT,Do LQ,Nguyen TA,Nguyen TT,Tran VL,Ho NA,Tran VC,Tran VS,Tran TPT

更新日期：2018-09-01 00:00:00

abstract：:A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

journal_title：Journal of Asian natural products research

authors： Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

更新日期：2009-01-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:Enterovirus 71 (EV71) is the major causative agent of hand foot and mouth disease. And EV71 causes epidemics worldwide, particularly in the Asia-Pacific region. Unfortunately, currently there is no approved vaccine or antiviral drug for EV71-induced disease prevention and therapy. In screening for anti-EV71 candidates...

journal_title：Journal of Asian natural products research

authors： Wang HQ,Meng S,Li ZR,Peng ZG,Han YX,Guo SS,Cui XL,Li YH,Jiang JD

更新日期：2013-01-01 00:00:00

abstract：:Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

journal_title：Journal of Asian natural products research

authors： Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

更新日期：2006-12-01 00:00:00

abstract：:A novel oxybis cresol compound named verticilatin (1), together with two known compounds, 5-methylresorcinol (2) and 2,4-dihydroxy-3,6-dimethylbenzaldehyde (3), was isolated from cultures of the insect pathogenic fungi Paecilomyces verticillatus. The structures of compounds were determined by extensive spectroscopic a...

journal_title：Journal of Asian natural products research

authors： Wei PY,Li L,Yang CG,Luo DQ,Zheng ZH,Lu XH,Shi BZ

更新日期：2014-12-01 00:00:00

abstract：:One kinds of glycolipid (SBI) have been isolated from the marine brown alga Sargassum hemiphyllum (Turn.) Ag. The structures of SBI have been determined as the sodium salt of 1-0-acyl-3-0-(6'-sulfo-alpha-D-quinovopyrannosyl) glycerol (acyl: tetradecanoyl, pentadecanoyl, 11-hexadecenoyl, hexadecanoyl, 10,13-octadecadie...

journal_title：Journal of Asian natural products research

authors： Cui Z,Li YS,Liu HB,Yuan D,Lu BR

更新日期：2001-01-01 00:00:00

abstract：:A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

更新日期：2013-01-01 00:00:00

abstract：:Two rarely phenolic acid-substituted alloses (1, 2) and one new glucoside (3), as well as nine known compounds (4-12) were isolated from rhizomes of Cibotium barometz (L.) J. Sm. Structures of 1-3 were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated f...

journal_title：Journal of Asian natural products research

authors： Li L,Xie MP,Sun H,Lu AQ,Zhang B,Zhang D,Wang SJ

更新日期：2019-10-01 00:00:00

abstract：:Three new polyoxypregnane glycosides, tenacigenosides F-H (1-3), were isolated from the stems of Marsdenia tenacissima. The structures of these new compounds were elucidated from 1D and 2D NMR spectra, as well as from HR-MS and acid hydrolysis. ...

journal_title：Journal of Asian natural products research

authors： Wang XL,Peng SL,Ding LS

更新日期：2010-08-01 00:00:00

abstract：:A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. A...

journal_title：Journal of Asian natural products research

authors： Pang X,Li NN,Yu HS,Kang LP,Yu HY,Song XB,Fan GW,Han LF

更新日期：2019-10-01 00:00:00

abstract：:Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoside (1) and 4-beta-D-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranosi...

journal_title：Journal of Asian natural products research

authors： Li FS,Dou DQ,Xu L,Chi XF,Kang TG,Kuang HX

更新日期：2009-07-01 00:00:00

abstract：:Chromatographic separation of the ethyl acetate soluble part of the methanolic extract from Seriphidium stenocephalum yielded three new compounds: stenocepflavone (1), stenocepflavan (2), and stenocephol (3), together with cirsimaritin (4), 5,7,5'-trihydroxy-3',4',6-trimethoxyflavone (5), 5,6,7,5'-tetrahydroxy-4'-meth...

journal_title：Journal of Asian natural products research

authors： Shafiq N,Riaz N,Ahmed S,Ashraf M,Ejaz SA,Ahmed I,Saleem M,Touseef MI,Tareen RB,Jabbar A

更新日期：2013-01-01 00:00:00

abstract：:Five new phenolic glycosides, 2-hydroxy-(2'E)-prenyl benzoate-2,4'-di-O-β-D-glucopyranoside (1), 2-hydroxy-(2'E)-prenyl benzoate-2-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (2), 4-methylphenol-1-O-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (3), 4-methylphenol-1-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyr...

journal_title：Journal of Asian natural products research

authors： Zhou Y,Ren HC,Qin RD,Zhang QY,Liang H

更新日期：2014-01-01 00:00:00

abstract：:Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

journal_title：Journal of Asian natural products research

authors： Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

更新日期：2013-11-01 00:00:00

abstract：:Two new saponins, capilliposide G (1) and capilliposide H (2), were isolated from the whole plants of Lysimachia capillipes. Their structures were determined by 1D and 2D NMR, MS technique and chemical methods. ...

journal_title：Journal of Asian natural products research

authors： Tian JK,Xu LZ,Zou ZM,Yang SL

更新日期：2006-07-01 00:00:00

abstract：:Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Qi Y,Zhao DK,Zi SH,Zhang LM,Guo CX,Li GQ,Xun JJ,Shen Y

更新日期：2016-01-01 00:00:00

abstract：:Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

journal_title：Journal of Asian natural products research

authors： Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

更新日期：2015-01-01 00:00:00

abstract：:Three series of sulfonate derivatives of paeonol were synthesized and screened in vitro for their anti-oomycete activity against P. capsici, respectively. Among all the compounds, 4m displayed the best promising and pronounced anti-oomycete activity against P. capsici than zoxamide, with the EC50 values of 24.51 and 2...

journal_title：Journal of Asian natural products research

authors： Tian YE,Sun D,Han XX,Yang JM,Zhang S,Feng NN,Zhu LN,Xu ZY,Che ZP,Liu SM,Lin XM,Jiang J,Chen GQ

更新日期：2020-02-03 00:00:00

abstract：:Two new drimane sesquiterpenoids, 11,12-dihydroxy-15-drimeneoic acid (1) and 3α,11,15-trihydroxydrimene (2), were isolated from cultures of the basidiomycete Agaricus arvensis, together with one known compound 3β,11,12-trihydroxydrimene (3). Their structures were established by means of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Ding JH,Li ZH,Dong ZJ,Feng T,Zhang HB,Liu JK

更新日期：2013-01-01 00:00:00

abstract：:During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

journal_title：Journal of Asian natural products research

authors： Guan YY,Li SZ,Lei PS

更新日期：2017-05-01 00:00:00

abstract：:Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combination with chemical reactions. ...

journal_title：Journal of Asian natural products research

authors： Li HM,Wan DW,Li RT

更新日期：2015-01-01 00:00:00

abstract：:A new sulphonoglycolipid, crassicaulisine, has been isolated from the red alga Chondria crassicaulis Harv.. Four known compounds were also found from the title plant. The structure of the new compound was elucidated on the basis of chemical reactions and spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Shao ZY,Cai JN,Ye QZ,Guo YW

更新日期：2002-09-01 00:00:00

abstract：:A new triterpenoid, 11α,12α-epoxy-3β-hydroxy-24-nor-olean-4(23)-en-28,13β-olide (1), and a new glycoside, benzyl 2-O-β-d-apiofuranosyl-(1 → 2)-β-d-glucopyranosyl benzoate (2), together with eight known triterpenoids (3-10), were isolated from Pilea cavaleriei subsp. cavaleriei. Their structures were established on the...

journal_title：Journal of Asian natural products research

authors： Ren HC,Qin RD,Wang Q,Cheng W,Zhang QY,Liang H

更新日期：2012-01-01 00:00:00

abstract：:From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

journal_title：Journal of Asian natural products research

authors： Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

更新日期：2012-01-01 00:00:00

abstract：:A new amide alkaloid, N-(3',4',5'-trimethoxy-cis-cinnamoyl)pyrrolidine (1), named sarmentomicine was isolated from the ethanol extract of the leaves of Malayan Piper sarmentosum, together with two known phenylpropanoids. Their structures were elucidated on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Sim KM,Mak CN,Ho LP

更新日期：2009-08-01 00:00:00

abstract：:A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...

journal_title：Journal of Asian natural products research

authors： Chai MY

更新日期：2020-03-01 00:00:00

abstract：:Three new alkaloids namely 8-(4-hydroxyphenyl)-6-methoxy-3,4-dihydroisoquinolin-1(2H)-one (1), 4-aminonigellidine (2), and N-[(4-hydroxy-2-isopropyl-5-methyl)]phenylurea (3), along with six known ones (4-9), were isolated from the seeds of Nigella glandulifera. The structures of 1-3 were determined through spectroscop...

journal_title：Journal of Asian natural products research

authors： Guo WH,Li XM,Huang SS,Yang MH,Kong LY

更新日期：2017-01-01 00:00:00

abstract：:Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...

journal_title：Journal of Asian natural products research

authors： Baloch IB,Baloch MK

更新日期：2010-07-01 00:00:00

abstract：:Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). The first total synthesis of samoamide A was achieved by employing a strategy of a s...

journal_title：Journal of Asian natural products research

authors： Chang Q,Li YL,Zhao X

更新日期：2019-02-01 00:00:00