Abstract:
:Two rarely phenolic acid-substituted alloses (1, 2) and one new glucoside (3), as well as nine known compounds (4-12) were isolated from rhizomes of Cibotium barometz (L.) J. Sm. Structures of 1-3 were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated for the hepatoprotective activities against APAP-induced HepG2 cell damage. Compounds 1, 4-7, 10 exhibited significant hepatoprotective activities, even more strongly than positive control, bicycol. In addition, compounds 1 and 9 could reduce PC12 cell death induced by serum deprivation.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Li L,Xie MP,Sun H,Lu AQ,Zhang B,Zhang D,Wang SJdoi
10.1080/10286020.2018.1563076subject
Has Abstractpub_date
2019-10-01 00:00:00pages
947-953issue
10eissn
1028-6020issn
1477-2213journal_volume
21pub_type
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journal_title:Journal of Asian natural products research
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journal_title:Journal of Asian natural products research
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journal_title:Journal of Asian natural products research
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