Abstract:
:Three new alkylated benzoquinones, 2-hydroxy-5-ethoxy-3-nonyl-1,4-benzoquinone (1), 5-O-butyl-embelin (2), and 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone (3), together with seven known analogues (4-10), were isolated from the stems and twigs of mangrove plant, Aegiceras corniculatum. Their structural elucidation was achieved by spectroscopic methods, chemical exchanging experiments, and semisynthesis method. The cytotoxic activities of all the isolated compounds were evaluated by MTT assay. Compounds 1, 2, 8, 9, and 10 possess varying degrees of selective cytotoxicity against HL-60, HepG2, BGC-823, and A2780 cell lines.[Formula: see text].
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Li Y,Dong C,Xu MJ,Lin WHdoi
10.1080/10286020.2018.1540604subject
Has Abstractpub_date
2020-02-01 00:00:00pages
121-130issue
2eissn
1028-6020issn
1477-2213journal_volume
22pub_type
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