A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.

abstract：:Phytochemical investigations of the whole plant of Stachys parviflora (Lamiaceae) resulted in the isolation of two new phenethyl alcohol glycosides. The structures of the new compounds named parviflorosides A and B were established as 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-E-caffeoyl-bet...

journal_title：Journal of Asian natural products research

authors： Ahmad VU,Arshad S,Bader S,Ahmed A,Iqbal S,Tareen RB

更新日期：2006-01-01 00:00:00

abstract：:Suberoylanilide hydroxamic acid (1), as well as other histone deacetylase (HDAC) inhibitors, are promising, targeted anticancer agents. Curcumin (2), a possible antitumor agent, exhibits a HDAC inhibiting effect but with a different mechanism, and was proposed to synergize with other drugs, including HDAC inhibitors. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Lu N,Yan Z,Wang N

更新日期：2010-05-01 00:00:00

abstract：:Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

journal_title：Journal of Asian natural products research

authors： Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

更新日期：2015-01-01 00:00:00

abstract：:Four spiroalkaloids, including a new compound shensongine A (1), were isolated from the anti-arrhythmic TCM formula Shensong Yangxin capsule. Their structures were determined on the basis of spectroscopic analysis. Compounds 1 and 3 displayed cardiovascular activities by shortened APD in rat myocardial cells. These co...

journal_title：Journal of Asian natural products research

authors： Ding B,Dai Y,Hou YL,Yao XS

更新日期：2015-05-01 00:00:00

abstract：:Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

journal_title：Journal of Asian natural products research

authors： Mu LH,Li JB,Yang JZ,Zhang DM

更新日期：2007-09-01 00:00:00

abstract：:Two new polyketides, 3,11-dihydroxy-6,8-dimethyldodecanoic acid (1) and trichopyrone B (2), together with two known polyketides, sorbicillin (3) and penicillone A (4), have been isolated from the cultures broth of the fungus Penicillium decumbens. Their structures were elucidated by extensive spectroscopic analysis. A...

journal_title：Journal of Asian natural products research

authors： Lin S,Wu YZ,Chen KY,Ye J,Yang XW,Zhang WD

更新日期：2018-05-01 00:00:00

abstract：:In this paper, the structure-activity relationships of chemically modified uronic acid polymer fragments from brown algae with regard to their antioxidant effects on H2O2-damaged lymphocyte were studied. The results indicated that the most potent antioxidant activity was obtained from the sulfated polysaccharide with ...

journal_title：Journal of Asian natural products research

authors： Hu JF,Gen MY,Zhang JT,Jiang HD

更新日期：2001-01-01 00:00:00

abstract：:(-)-Incrustoporin (1) has been synthesized using aldol condensation of ethyl p-tolyl-acetate (2) and (2R)-benzoyloxy-butanal (3), followed by acid-catalyzed deprotection of the benzoyl group, lactone ring-closure, and elimination of the beta-OH in a one-pot manner. The aldehyde 3 was prepared from the commercially ava...

journal_title：Journal of Asian natural products research

authors： Yu Q,Liu JF,Wu YL

更新日期：1999-01-01 00:00:00

abstract：:Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataoside...

journal_title：Journal of Asian natural products research

authors： Yin YQ,Kong LY

更新日期：2008-03-01 00:00:00

abstract：:A new natural coumarin, angepubebisin (1), and a new furan, angepubefurin (2), together with the five known compounds, umbelliferone, angelol B (3), ulopterol (4), peucedanol (5), and scopoletin, were isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The structures of angepubebisin (1) an...

journal_title：Journal of Asian natural products research

authors： Yang XW,Zhang CY,Zhang BG,Lu Y,Luan JW,Zheng QT

更新日期：2009-08-01 00:00:00

abstract：:A new phenanthraquinone, named bauhinione (1), has been isolated from Bauhinia variegata L., and its structure has been elucidated as 2,7-dimethoxy-3-methyl-9,10-dihydrophenanthrene-1,4-dione on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao YY,Cui CB,Cai B,Han B,Sun QS

更新日期：2005-12-01 00:00:00

abstract：:Dehydrozingerone analogs and related compounds were screened as potential antitumor promoters by using the in vitro short-term 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced Epstein-Barr virus early antigen activation assay. Among the 40 synthesized compounds, the prenylated analogs 16 and 34-36 showed the most si...

journal_title：Journal of Asian natural products research

authors： Tatsuzaki J,Nakagawa-Goto K,Tokuda H,Lee KH

更新日期：2010-03-01 00:00:00

abstract：:Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3-9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1 and 2 possessed the potent anti-complement and anti-inflammatory activities. ...

journal_title：Journal of Asian natural products research

authors： Wang MY,Zhang Y,Zhang H,Feng XR,Li XB

更新日期：2019-06-01 00:00:00

abstract：:A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

journal_title：Journal of Asian natural products research

authors： Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

更新日期：2008-05-01 00:00:00

abstract：:Three new xanthone glycosides, securixanside A (1), securixanside B (2), and securixanside C (3) were isolated from the stems of Securidaca inappendiculata. These compounds were characterized by spectrometric and chemical methods, including FABMS and one- and two-dimensional NMR experiments. ...

journal_title：Journal of Asian natural products research

authors： Yang XD,An N,Xu LZ,Yang SL

更新日期：2002-06-01 00:00:00

abstract：:Four new lignan glycosides (1-4), named procumbenosides I, K, L, and M, together with cleistanthin B (5) reported for the first time in the genus Justicia, and 5 other known arylnaphthalene lignan glycosides (6-10) were isolated from the whole plant of Justicia procumbens. The structures of the new compounds were eluc...

journal_title：Journal of Asian natural products research

authors： Jin H,Yang S,Dong JX

更新日期：2017-01-01 00:00:00

abstract：:Two new homoisoflavonoids, ( ± )-5,7-dihydroxy-8-methyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (1) and ( ± )-5,7-dihydroxy-6,8-dimethyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (2), along with two known homoisoflavonoids, 5,7-dihydroxy-6-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (3) and disporopsin (4), were isola...

journal_title：Journal of Asian natural products research

authors： Li LM,Yuan QP,Chen G

更新日期：2014-01-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

journal_title：Journal of Asian natural products research

authors： Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

更新日期：2018-05-01 00:00:00

abstract：:The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be a new strategy for treating epilepsy. So far, no studies have shown whether the ...

journal_title：Journal of Asian natural products research

authors： Peng YC,Wang S,Zhang Y,Huang LJ,Wang XL,Peng Y

更新日期：2019-09-01 00:00:00

abstract：:Phytochemical analysis of the MeOH extract of the fruiting bodies of Stropharia aeruginosa resulted in the isolation of three lanostane triterpenoids, aeruginosols A, B and C. The structures of the new compounds were determined by spectroscopic analysis. The biological activities of aeruginosols A, B and C were examin...

journal_title：Journal of Asian natural products research

authors： Shiono Y,Sugawara H,Nazarova M,Murayama T,Takahashi K,Ikeda M

更新日期：2007-09-01 00:00:00

abstract：:Two new saponins, capilliposide G (1) and capilliposide H (2), were isolated from the whole plants of Lysimachia capillipes. Their structures were determined by 1D and 2D NMR, MS technique and chemical methods. ...

journal_title：Journal of Asian natural products research

authors： Tian JK,Xu LZ,Zou ZM,Yang SL

更新日期：2006-07-01 00:00:00

abstract：:Three new compounds, namely massonside C (1), massonianoside F (2), and 3, 8-dimethyl- herbacetin-7-O-β-D-glucopyranoside (3), together with five known compounds (4-8), were isolated from the fresh needles of Pinus massoniana. Their structures were established by 1D, 2D NMR, HRMS and comparison with the literature dat...

journal_title：Journal of Asian natural products research

authors： Xiao YC,Shi ZF,Yan CQ,Tang QX,Zhao MX,Liu LT,Huang QS,Ye L,Xu K,Ke X

更新日期：2020-08-01 00:00:00

abstract：:A new hTopo I isomerase inhibitor, (+)-3,3',7,7',8,8'-hexahydroxy-5,5'-dimethylbianthraquinone (2240A), was isolated from the mangrove endophytic fungus no. 2240 collected from an estuarine mangrove at the South China Sea coast. Its structure was elucidated by spectral analyses including two-dimensional NMR, HR-EI-MS,...

journal_title：Journal of Asian natural products research

authors： Tan N,Cai XL,Wang SY,Pan JH,Tao YW,She ZG,Zhou SN,Lin YC,Vrijmoed LL

更新日期：2008-07-01 00:00:00

abstract：:A new ester, 2-(4'-hydroxyphenyl)ethyl dotriacontanoate (1), and a new inseparable mixture of octacosan-1,28-dioldiferulate and triacontan-1,30-dioldiferulate (2) were isolated from the stem barks of Stereospermum acuminatissimum, along with 24 known compounds including 4 triterpenoids, 11 anthraquinones, 2 lignans, 3...

journal_title：Journal of Asian natural products research

authors： Sob SV,Wabo HK,Tang CP,Tane P,Ngadjui BT,Ye Y

更新日期：2011-12-01 00:00:00

abstract：:Two new neolignan glucosides named (7S, 8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxyl-7'-oxo-8-4'-oxyneolignan-4-O-β-D-glucopyranoside and (7'S, 8'R, 8S)-4,4',9'-trihydroxy-3,3'-dimethoxy-7',9-epoxylignan-7-oxo-4-O-β-D-glucopyranosyl-4'-O-β-D-glucopyranoside, together with two small molecular peptides named 3-benzyl-6-(1-...

journal_title：Journal of Asian natural products research

authors： Yang YN,Zhang F,Feng ZM,Jiang JS,Zhang PC

更新日期：2012-01-01 00:00:00

abstract：:A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using physical and spectroscopic methods. The compounds showed weak to moderate insecticidal activities agai...

journal_title：Journal of Asian natural products research

authors： Makenzi AM,Manguro LOA,Owuor PO

更新日期：2020-09-15 00:00:00

abstract：:We present the synthesis of enantiomerically pure (S)-α-methyl-serine methyl ester hydrochloride from 2-methyl-3-((4-(trifluoromethyl)benzyl)oxy)propanal and di-p-chlorobenzyl azodicarboxylate via asymmetrically catalyzed amination with naphthylalanine derivative catalyst. The application of the organocatalyst of D-3-...

journal_title：Journal of Asian natural products research

authors： Xiao Q,Tang YF,Xie P

更新日期：2020-01-01 00:00:00

abstract：:Pseudolaric acid-B (PLAB), a diterpene acid, was isolated from the root and trunk barks of Pseudolarix kaempferi. It showed antifungal and anti-fertility effects as well as cytotoxic activities in previous studies. The present study investigates cytotoxic activity on cultured human cancer cells, inhibition on the grow...

journal_title：Journal of Asian natural products research

authors： Liu B,Chen H,Lei ZY,Yu PF,Xiong B

更新日期：2006-04-01 00:00:00

abstract：:Muricatenol (1) is a new C37 non-THF ring acetogenin with four hydroxyls and one isolated double bond in the long aliphatic chain. 2,4-cis-Gigantetrocinone (2) and 2,4-trans-gigantetrocinone (3) have been isolated as their acetates by preparative TLC. 2,4-trans-Isoannonacin-10-one (4) and 2,4-trans-isoannonacin (5) ha...

journal_title：Journal of Asian natural products research

authors： Li DY,Yu JG,Zhu JX,Yu DL,Luo XZ,Sun L,Yang SL

更新日期：2001-01-01 00:00:00