Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.

abstract：:A new triterpene glycoside mutongsaponin F (1), together with five known saponins and two known lipids, was isolated from the 70% ethanol extract of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd. Their structures were elucidated on the basis of the spectroscopic analysis and physicochemica...

journal_title：Journal of Asian natural products research

authors： Gao HM,Wang ZM,Wang WH

更新日期：2009-12-01 00:00:00

abstract：:A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain...

journal_title：Journal of Asian natural products research

authors： Xie XL,Ye GH,Xue JJ,Su T,Tang GH,Li W,Yin S

更新日期：2020-05-01 00:00:00

abstract：:Muricatenol (1) is a new C37 non-THF ring acetogenin with four hydroxyls and one isolated double bond in the long aliphatic chain. 2,4-cis-Gigantetrocinone (2) and 2,4-trans-gigantetrocinone (3) have been isolated as their acetates by preparative TLC. 2,4-trans-Isoannonacin-10-one (4) and 2,4-trans-isoannonacin (5) ha...

journal_title：Journal of Asian natural products research

authors： Li DY,Yu JG,Zhu JX,Yu DL,Luo XZ,Sun L,Yang SL

更新日期：2001-01-01 00:00:00

abstract：:Four new furostanol glycosides were isolated from the flowers of Hosta plantaginea (Lam.) Aschers. On the basis of spectroscopic methods including 1D and 2D NMR experiments, their structures were elucidated as 26-O-β-d-glucopyranosyl-(25R)-22-O-methyl-5α-furostan-2α,3β,22ξ,26-tetrol 3-O-α-l-rhamnopyranosyl-(1 → 4)-O-β...

journal_title：Journal of Asian natural products research

authors： Li XJ,Wang L,Xue PF,Xie HX,Wei H,Wang J

更新日期：2015-01-01 00:00:00

abstract：:A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of ...

journal_title：Journal of Asian natural products research

authors： Zhao W,Deng AJ,Du GH,Zhang JL,Li ZH,Qin HL

更新日期：2009-01-01 00:00:00

abstract：:A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C ...

journal_title：Journal of Asian natural products research

authors： Yang DL,Mei WL,Zeng YB,Guo ZK,Wei DJ,Liu SB,Wang QH,Dai HF

更新日期：2013-01-01 00:00:00

abstract：:Eight tetranortriterpenoids (1-8) and two sesquiterpenoids (9 and 10) including two new compounds, cineracipadesin G (1) and 1β-hydroperoxy-6α-hydroxy-eudesm-4(15)-ene (9), were isolated from the EtOAc extract of branches of Cipadessa cinerascens. The structures of two new compounds were elucidated by 1D and 2D NMR an...

journal_title：Journal of Asian natural products research

authors： Fu LR,Ma QY,Huang SZ,Dai HF,Guo ZK,Yu ZF,Zhao YX

更新日期：2014-01-01 00:00:00

abstract：:A new minor sesquiterpene lactone glucoside, ixerin ZA (1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-[6'-(p-metheoxyphenylacetyl)]-beta-glucopyranoside on the basis of sp...

journal_title：Journal of Asian natural products research

authors： He WF,Xu BB,Pan JC,Lu JC,Song SJ,Xu SX

更新日期：2006-09-01 00:00:00

abstract：:Five new phenolic glycosides, 2-hydroxy-(2'E)-prenyl benzoate-2,4'-di-O-β-D-glucopyranoside (1), 2-hydroxy-(2'E)-prenyl benzoate-2-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (2), 4-methylphenol-1-O-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (3), 4-methylphenol-1-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyr...

journal_title：Journal of Asian natural products research

authors： Zhou Y,Ren HC,Qin RD,Zhang QY,Liang H

更新日期：2014-01-01 00:00:00

abstract：:Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

journal_title：Journal of Asian natural products research

authors： Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

更新日期：2015-01-01 00:00:00

abstract：:A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

journal_title：Journal of Asian natural products research

authors： Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

更新日期：2007-04-01 00:00:00

abstract：:Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

journal_title：Journal of Asian natural products research

authors： Jing WY,Jiang C,Ji F,Hua HM,Li ZL

更新日期：2013-11-01 00:00:00

abstract：:Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

journal_title：Journal of Asian natural products research

authors： Mu LH,Li JB,Yang JZ,Zhang DM

更新日期：2007-09-01 00:00:00

abstract：:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells an...

journal_title：Journal of Asian natural products research

authors： Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YH

更新日期：2009-09-01 00:00:00

abstract：:Two new diterpenoid glycosides, fructusnoids D (1) and E (2), and two new monoterpenoid glycosides (3, 4), together with three known diterpenoid glycosides (5-7) and three known monoterpenoid glycosides (8-10), were isolated from the fruits of Xanthium chinense. Their structures were elucidated by spectrometric analys...

journal_title：Journal of Asian natural products research

authors： Cheng Y,Fu J,Chen L,Li LL,Qu J

更新日期：2019-03-01 00:00:00

abstract：:A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

journal_title：Journal of Asian natural products research

authors： Kong LY,Zhi F

更新日期：2003-09-01 00:00:00

abstract：:Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

journal_title：Journal of Asian natural products research

authors： Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

更新日期：2003-06-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:Four types of piscidinol A derivatives were synthesized and evaluated their ability to inhibit HIV-1 protease to understand their structure-activity relationships. Of these tirucallane-type triterpene derivatives, an A-seco derivative (1b) moderately inhibited human immunodeficiency virus (HIV) protease (IC50 38.2 μM)...

journal_title：Journal of Asian natural products research

authors： Wei Y,Ma CM,Jiang TB,Du J,Zhou X,Liu GQ,Hattori M

更新日期：2015-01-01 00:00:00

abstract：:A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two pr...

journal_title：Journal of Asian natural products research

authors： Zhang HJ,Yang XP,Wang KW

更新日期：2010-04-01 00:00:00

abstract：:A phytochemical investigation on the whole plant of Aconitum tanguticum (Ranunculaceae) resulted in the isolation and characterization of two new phenylpropanoid glycosides (1 and 2). Their structures were elucidated as 4-hydroxyphenethoxy-8-O-β-d-[6-O-(4-O-β-d-glucopyranosyl)-sinapoyl]-glucopyranoside (1) and 3,4-dim...

journal_title：Journal of Asian natural products research

authors： Li YR,Xu L,Li C,Wang ZM,Yang LX

更新日期：2014-01-01 00:00:00

abstract：:Two new indole-diterpenoids named penijanthine B and penitrem H were isolated from the metabolites of the fungus Penicilliumcrustosum YN-HT-15, which was isolated from the red soil of Yunnan Province of China. The structures were determined on spectroscopic analyses and CD spectra. ...

journal_title：Journal of Asian natural products research

authors： Su SS,Song AH,Chen G,Wang HF,Li ZQ,Pei YH

更新日期：2014-01-01 00:00:00

abstract：:Our goals were to examine the dual-directional regulation effects of resveratrol (1) in vitro by using MCF-7 cells (estradiol receptor-positive cells), study its mechanism of action, and give a systematical analysis of the regulatory networks of each related factor. An MTT test and growth curve showed that the prolife...

journal_title：Journal of Asian natural products research

authors： Wang YZ,Cao B,Li SX,Zang ZH,Zhang JZ,Chen H

更新日期：2009-01-01 00:00:00

abstract：:The investigation of chemical constituents from the branches of Calophyllum inophyllum Linn led to the isolation of a new prenylated xanthone, named caloxanthone Q (1), together with three known compounds, 2-deprenylrheediaxanthone B (2), jacareubin (3), and 6-deoxyjacareubin (4). Their structures were completely eluc...

journal_title：Journal of Asian natural products research

authors： Wei DJ,Mei WL,Zhong HM,Zeng YB,Wu XD,Dai HF

更新日期：2011-03-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...

journal_title：Journal of Asian natural products research

authors： Chai MY

更新日期：2020-03-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1-2) and three known analogs (3-5) including a new natural product (5). Their structures were determined on the...

journal_title：Journal of Asian natural products research

authors： Sun ZH,Liang FL,Chen YC,Liu HX,Li HH,Zhang WM

更新日期：2016-11-01 00:00:00

abstract：:Two new bromophenols, (E)-3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methylpropenal (1) and 3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methyl-1-propanol (2), together with 11 known bromophenols (3-13), were isolated from the ethanolic extract of the brown alga Leathesia nana S. et G. Their structures have been elucidated by spe...

journal_title：Journal of Asian natural products research

authors： Xu XL,Fan X,Song FH,Zhao JL,Han LJ,Yang YC,Shi JG

更新日期：2004-09-01 00:00:00

abstract：:A new spirocyclic compound named (2S, 5S, 7S)-3α-hydroxyl-exogonic acid (1) was isolated from the liquid culture of entomogenous fungus Isaria cateniannulata. The structure and relative stereochemistry of 1 were elucidated by extensive spectroscopic analysis and by comparison of its NMR data with those of known compou...

journal_title：Journal of Asian natural products research

authors： Yang XL,Li ZZ,Zhang S,Yu H,Zhu HJ,Luo DQ

更新日期：2012-01-01 00:00:00