A new spirocyclic compound from the liquid culture of entomogenous fungus Isaria cateniannulata.

Abstract:

:A new spirocyclic compound named (2S, 5S, 7S)-3α-hydroxyl-exogonic acid (1) was isolated from the liquid culture of entomogenous fungus Isaria cateniannulata. The structure and relative stereochemistry of 1 were elucidated by extensive spectroscopic analysis and by comparison of its NMR data with those of known compound. Compound 1 showed weak inhibitory activity against HeLa with IC(50) value of 80.5 μg ml(- 1).

journal_name

J Asian Nat Prod Res

authors

Yang XL,Li ZZ,Zhang S,Yu H,Zhu HJ,Luo DQ

doi

10.1080/10286020.2012.707650

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

1093-6

issue

11

eissn

1028-6020

issn

1477-2213

journal_volume

14

pub_type

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