Four new diterpenoids isolated from the Euphorbia rapulum.

Abstract:

:Four new diterpenoids named 1-epi-9-hydroxydepressin (1), 1-epi-8-hydroxydepressin (2), 2,13,9-trihydroxy-labda-8(17),12(E),14-triene (3) and tagalsin I (4) were isolated from Euphorbia rapulum. The structures of these compounds were elucidated by means of various spectroscopic methods. All the isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and C6 cell lines, and compound 4 showed moderate selective activity against MCF-7 cell line with an IC50 value of 31.8 μM.

journal_name

J Asian Nat Prod Res

authors

Liu XX,Shang L,Huang C,Feng XS,Li W,Sha Y,Huang J,Wang JH

doi

10.1080/10286020.2016.1170813

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

823-30

issue

9

eissn

1028-6020

issn

1477-2213

journal_volume

18

pub_type

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