Abstract:
:Four new diterpenoids named 1-epi-9-hydroxydepressin (1), 1-epi-8-hydroxydepressin (2), 2,13,9-trihydroxy-labda-8(17),12(E),14-triene (3) and tagalsin I (4) were isolated from Euphorbia rapulum. The structures of these compounds were elucidated by means of various spectroscopic methods. All the isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and C6 cell lines, and compound 4 showed moderate selective activity against MCF-7 cell line with an IC50 value of 31.8 μM.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Liu XX,Shang L,Huang C,Feng XS,Li W,Sha Y,Huang J,Wang JHdoi
10.1080/10286020.2016.1170813subject
Has Abstractpub_date
2016-09-01 00:00:00pages
823-30issue
9eissn
1028-6020issn
1477-2213journal_volume
18pub_type
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