Phenol esters and other constituents from the stem barks of Stereospermum acuminatissimum.

abstract：:Andrographolide (1), a diterpenoid lactone isolated from a traditional herb (Andrographis paniculata), is known to possess potent anti-inflammatory activity. In this study, we investigated the anti-tumor effect of 1 on various cancer cell lines in vitro. It induced apoptosis of prostate cancer (PC-3) cells (the most s...

journal_title：Journal of Asian natural products research

authors： Zhao F,He EQ,Wang L,Liu K

更新日期：2008-05-01 00:00:00

abstract：:Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

journal_title：Journal of Asian natural products research

authors： Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

更新日期：2015-01-01 00:00:00

abstract：:Two new indole alkaloids, tryptoquivalines R and S, have been isolated from a marine-derived fungus Neosartorya sp.HN-M-3. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR experiments. ...

journal_title：Journal of Asian natural products research

authors： Xu N,Cao Y,Wang L,Chen G,Pei YH

更新日期：2013-07-01 00:00:00

abstract：:Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

journal_title：Journal of Asian natural products research

authors： Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

更新日期：2013-11-01 00:00:00

abstract：:Two new lignan glycosides forsythiayanoside A (1) and forsythiayanoside B (2), one new stereoisomer of lignan glycoside (+)-8-hydroxyepipinoresinol-4-O-β-D-glucopyranoside (3), together with seven known compounds (4-10), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. Compounds 4 and 10 were isolate...

journal_title：Journal of Asian natural products research

authors： Yan XJ,Peng Y,Liu ZX,Wen J,Liu QB,Li LZ,Song SJ

更新日期：2014-01-01 00:00:00

abstract：:A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

journal_title：Journal of Asian natural products research

authors： Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

更新日期：2008-05-01 00:00:00

abstract：:A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two pr...

journal_title：Journal of Asian natural products research

authors： Zhang HJ,Yang XP,Wang KW

更新日期：2010-04-01 00:00:00

abstract：:Suberoylanilide hydroxamic acid (1), as well as other histone deacetylase (HDAC) inhibitors, are promising, targeted anticancer agents. Curcumin (2), a possible antitumor agent, exhibits a HDAC inhibiting effect but with a different mechanism, and was proposed to synergize with other drugs, including HDAC inhibitors. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Lu N,Yan Z,Wang N

更新日期：2010-05-01 00:00:00

abstract：:Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%. ...

journal_title：Journal of Asian natural products research

authors： Zhang JX,Li ZY,Wang YC,Ma WB,Hou M,Cao SH,Tang KH,Dong HB

更新日期：2017-09-01 00:00:00

abstract：:A new diimide derivative, named (-)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthe...

journal_title：Journal of Asian natural products research

authors： Li CY,Ding WJ,Shao CL,She ZG,Lin YC

更新日期：2010-09-01 00:00:00

abstract：:A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

journal_title：Journal of Asian natural products research

authors： Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

更新日期：2012-01-01 00:00:00

abstract：:A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy...

journal_title：Journal of Asian natural products research

authors： Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JH

更新日期：2014-01-01 00:00:00

abstract：:Two new selaginellin derivatives selaginellin P (1) and selaginellin Q (2) were isolated from Selaginella tamariscina. The structures of 1 and 2 were established as 2,4'-dihydroxy-4-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene (1) and 2,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene (2) on the basis of spectroscopic m...

journal_title：Journal of Asian natural products research

authors： Xu KP,Li J,Zhu GZ,He XA,Li FS,Zou ZX,Tan LH,Cheng F,Tan GS

更新日期：2015-01-01 00:00:00

abstract：:During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

journal_title：Journal of Asian natural products research

authors： Guan YY,Li SZ,Lei PS

更新日期：2017-05-01 00:00:00

abstract：:Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

journal_title：Journal of Asian natural products research

authors： Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

更新日期：2015-01-01 00:00:00

abstract：:A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

更新日期：2013-01-01 00:00:00

abstract：:A new sterol, stigmast-5-ene-3beta,17alpha-diol (1), together with six known compounds, stigmast-5-ene-3beta-yl formate (2), stigmast-5-ene-3beta,7alpha-diol (3), stigmast-5-ene-7alpha-methoxy-3beta-ol (4), stigmast-5-ene-3-one (5), 3beta-sitostanol (6), and 3beta-sitosterol (7), was isolated from the fruits of Syzygi...

journal_title：Journal of Asian natural products research

authors： Chumkaew P,Kato S,Chantrapromma K

更新日期：2010-05-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

更新日期：2011-04-01 00:00:00

abstract：:A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

journal_title：Journal of Asian natural products research

authors： Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

更新日期：2007-04-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

journal_title：Journal of Asian natural products research

authors： Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

更新日期：2013-01-01 00:00:00

abstract：:Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

journal_title：Journal of Asian natural products research

authors： Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

更新日期：2003-06-01 00:00:00

abstract：:Two new lignans, 9-salicyl-(+)-isolariciresinol (1) and gaultheroside G (2), together with seven known compounds, were isolated from the ethanolic extract of the whole plant of Gaultheria yunnanensis. Their structures were determined by extensive NMR and MS analyses. Gaultheroside G (2) was found to have an unusual et...

journal_title：Journal of Asian natural products research

authors： Gao YP,Shen YH,Xu XK,Tian JM,Zeng HW,Lin S,Liu CM,Zhang WD

更新日期：2014-01-01 00:00:00

abstract：:Three new C(19)-diterpenoid alkaloids, umbrosumines A-C (1-3), and 11 known compounds (4-14) were isolated from the roots of Delphinium umbrosum. Their structures were elucidated on the basis of the spectroscopic data interpretation. ...

journal_title：Journal of Asian natural products research

authors： Chen FZ,Chen QH,Wang FP

更新日期：2010-06-01 00:00:00

abstract：:In this letter, (R)-muscone and (S)-muscone were prepared by optical resolution of dl-muscone using N,N'-dibenzyl-l-tartaramide or N,N'-dibenzyl-d-tartaramide, according to the method reported by Kunihiko Takabe. But we separated the diastereomers using EtOH instead of MeOH in the recrystallization step to get the goa...

journal_title：Journal of Asian natural products research

authors： Meng Y,Xiao Q,Bai JY,Xiao X,Zhang S,Zhu XY,Cheng GF,Yin DL

更新日期：2014-12-01 00:00:00

abstract：:A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...

journal_title：Journal of Asian natural products research

authors： Shi JX,Li YH,Wang X,Qin YQ,Zhang CY,Zhang X,Li CR,An MQ,Li LR,Lu SH,Huang J

更新日期：2018-11-01 00:00:00

abstract：:Methyl tortuoate D (1), together with five other known related bis-cembranoids, was isolated from Hainan soft coral Sarcophyton tortuosum. The structure of methyl tortuoate D (1a), firstly isolated and reported by Li et al. from the title organism, was corrected as 1 by an extensive analysis of its one-dimensional and...

journal_title：Journal of Asian natural products research

authors： Li YF,He LL,Liu HL,Liang LF,Zhang HB,Guo YW

更新日期：2013-01-01 00:00:00

abstract：:Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

journal_title：Journal of Asian natural products research

authors： Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

更新日期：2005-10-01 00:00:00

abstract：:Chromatographic separation of the ethyl acetate soluble part of the methanolic extract from Seriphidium stenocephalum yielded three new compounds: stenocepflavone (1), stenocepflavan (2), and stenocephol (3), together with cirsimaritin (4), 5,7,5'-trihydroxy-3',4',6-trimethoxyflavone (5), 5,6,7,5'-tetrahydroxy-4'-meth...

journal_title：Journal of Asian natural products research

authors： Shafiq N,Riaz N,Ahmed S,Ashraf M,Ejaz SA,Ahmed I,Saleem M,Touseef MI,Tareen RB,Jabbar A

更新日期：2013-01-01 00:00:00