Abstract:
:A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1) exerted inhibitory activity against the production of nitric oxide in RAW264.7 stimulated by lipopolysaccharide.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JHdoi
10.1080/10286020.2013.841675subject
Has Abstractpub_date
2014-01-01 00:00:00pages
216-21issue
2eissn
1028-6020issn
1477-2213journal_volume
16pub_type
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