Chemical constituents of the stems of Ephedra sinica.

Abstract:

:A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of Ephedra sinica, a famous traditional Chinese herbal medicine. The structures of 1 and 2 were determined by spectroscopic methods, including 1D- and 2D-NMR experiments as well as HR-EI-MS analysis.

journal_name

J Asian Nat Prod Res

authors

Zhao W,Deng AJ,Du GH,Zhang JL,Li ZH,Qin HL

doi

10.1080/10286020802573552

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

168-71

issue

2

eissn

1028-6020

issn

1477-2213

pii

908699702

journal_volume

11

pub_type

杂志文章
  • Microbial hydroxylation of cinobufagin by Mucor spinosus.

    abstract::Mucor spinosus has been employed for the biotransformation of cinobufagin (1) to afford three metabolites. On the basis of their physico-chemical data, the structures of the transformation products have been characterized as 1beta-hydroxy-cinobufagin (2), 12beta-hydroxy-cinobufagin (3) and 1beta,12beta-dihydroxy-cinob...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020410001690136

    authors: Zhang W,Ye M,Qu GQ,Wu WY,Chen YJ,Guo DA

    更新日期:2005-06-01 00:00:00

  • New iridoids from Pedicularis artselaeri.

    abstract::Three new iridoids, named artselaenin I, II and III, were isolated from the whole plants of Pedicularis artselaeri, along with 11 known compounds, 8-epiloganic acid, 7-deoxy-8-epiloganic acid, plantarenaloside, mussaenoside, lariciresinol-4-O-beta-D-glucoside, lariciresinol-4'-O-beta-D-glucoside, alaschaniosideA, cirt...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286029808039851

    authors: Su BN,Zhai JJ,Jia ZJ

    更新日期:1998-01-01 00:00:00

  • Three lanostane triterpenoids, aeruginosols A, B and C, from the fruiting bodies of Stropharia aeruginosa.

    abstract::Phytochemical analysis of the MeOH extract of the fruiting bodies of Stropharia aeruginosa resulted in the isolation of three lanostane triterpenoids, aeruginosols A, B and C. The structures of the new compounds were determined by spectroscopic analysis. The biological activities of aeruginosols A, B and C were examin...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020600882254

    authors: Shiono Y,Sugawara H,Nazarova M,Murayama T,Takahashi K,Ikeda M

    更新日期:2007-09-01 00:00:00

  • A new natural naphtho[1,2-b]furan from the leaves of Cassia fistula.

    abstract::A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.812077

    authors: Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

    更新日期:2013-11-01 00:00:00

  • Two new diterpenoid dimers, fritillebinide D and E, from bulbs of Fritillaria ebeiensis.

    abstract::Two new ent-kaurane diterpenoid dimers, fritillebinide D (1) and fritillebinide E (2), were isolated from bulbs of Fritillaria ebeiensis G.D. Yu et G.Q. Ji. Their structures have been determined to be ent-3beta-acetoxy-kauran-16beta, 17-acetal ent-3beta-acetoxy-16beta-kauran-17(R)-aldehyde (1) and ent-3beta-acetoxy-ka...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602021000049113

    authors: Ruan HL,Zhang YH,Wu JZ,Sun HD,Fujita T

    更新日期:2002-12-01 00:00:00

  • Two new components from Gnetum pendulum.

    abstract::Two new compounds, 3-O-(13-hydroxy-9Z,11E,15E-octadecatrienoyl) cycloeucalenol (1) and 24'-hydroxy-tetracosyl ferulate (2), together with one known compound, tetracosyl ferulate (3), were isolated from the dried stems of Gnetum pendulum. The two new compounds were structurally elucidated by spectroscopic and chemical ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802318958

    authors: Xiang WS,Wang JD,Wang XJ,Zhang J

    更新日期:2008-11-01 00:00:00

  • New phenolic glycosides from Pilea cavaleriei.

    abstract::Five new phenolic glycosides, 2-hydroxy-(2'E)-prenyl benzoate-2,4'-di-O-β-D-glucopyranoside (1), 2-hydroxy-(2'E)-prenyl benzoate-2-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (2), 4-methylphenol-1-O-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (3), 4-methylphenol-1-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyr...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.922552

    authors: Zhou Y,Ren HC,Qin RD,Zhang QY,Liang H

    更新日期:2014-01-01 00:00:00

  • Spiroalkaloids from Shensong Yangxin capsule.

    abstract::Four spiroalkaloids, including a new compound shensongine A (1), were isolated from the anti-arrhythmic TCM formula Shensong Yangxin capsule. Their structures were determined on the basis of spectroscopic analysis. Compounds 1 and 3 displayed cardiovascular activities by shortened APD in rat myocardial cells. These co...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1047354

    authors: Ding B,Dai Y,Hou YL,Yao XS

    更新日期:2015-05-01 00:00:00

  • Synthesis and cytotoxic activity of two steroids: icogenin aglycone analogs.

    abstract::During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1228633

    authors: Guan YY,Li SZ,Lei PS

    更新日期:2017-05-01 00:00:00

  • Two new C19-diterpenoid alkaloids from Aconitum straminiflorum.

    abstract::Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1107545

    authors: Qi Y,Zhao DK,Zi SH,Zhang LM,Guo CX,Li GQ,Xun JJ,Shen Y

    更新日期:2016-01-01 00:00:00

  • Manuifolin Q, an unusual 4-aryl-substituted isoflavan from Maackia tenuifolia.

    abstract::Manuifolin Q (1), an unusual 4-aryl-substituted isoflavan, was isolated from the roots of Maackia tenuifolia. Its absolute configuration was determined as (3R,4R)-3,4-trans-7,2'-dihydroxy-4'-methoxy-4-[(2,4-dihydroxy-5-(1,1-dimethyl-2-propenyl)]-phenyl-isoflavan, on the basis of spectroscopic analysis. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000119817

    authors: Zeng JF,Tan CH,Zhu DY

    更新日期:2004-03-01 00:00:00

  • Two novel lignans from Gaultheria yunnanensis.

    abstract::Two new lignans, 9-salicyl-(+)-isolariciresinol (1) and gaultheroside G (2), together with seven known compounds, were isolated from the ethanolic extract of the whole plant of Gaultheria yunnanensis. Their structures were determined by extensive NMR and MS analyses. Gaultheroside G (2) was found to have an unusual et...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.898634

    authors: Gao YP,Shen YH,Xu XK,Tian JM,Zeng HW,Lin S,Liu CM,Zhang WD

    更新日期:2014-01-01 00:00:00

  • Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi).

    abstract::Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin-secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11'-methyl-oleosidyl-(7'-->6'')]-beta-D-glucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectro...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701394514

    authors: Xiao K,Song QH,Zhang SW,Xuan LJ

    更新日期:2008-01-01 00:00:00

  • Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L.

    abstract::Five labdane-type diterpenes, vitexilactone (1), (rel 5S,6R,8R,9R,10S)-6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (2), rotundifuran (3), vitetrifolin D (4), and vitetrifolin E (5), have been isolated from Vitex trifolia L., a Chinese folk medicine used to treat cancers, as new cell cycle inhibitors and apoptosis in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001617165

    authors: Li WX,Cui CB,Cai B,Yao XS

    更新日期:2005-04-01 00:00:00

  • Bioactive amides from Polygonum cuspidatum.

    abstract::One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2021.1873298

    authors: Zhang X,Liu F,Feng ZM,Jiang JS,Yang YN,Zhang PC

    更新日期:2021-01-18 00:00:00

  • Two new caffeoyl conjugation from Erigeron breviscapus.

    abstract::Two new constituents with a novel basic skeleton were isolated from Erigeron breviscapus. On the basis of chemical and spectroscopic evidences, the structures of the new compounds were elucidated as 1R,3R-dihydroxy-4S,5R-dicaffeoyloxy cyclohexane carboxylic acid methyl ester (V), 1,4-dihydroxy-3R,5R-dicaffeoyloxy cycl...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008041367

    authors: Zhang WD,Tam HT,Chen WS,Kong DY,Li HT,Wang YH,Fouraste I

    更新日期:2000-01-01 00:00:00

  • Isolation, X-ray crystal structure of the new diterpene and identification of others lignans and flavonoids from the fresh needles of Pinus massoniana.

    abstract::Three new compounds, namely massonside C (1), massonianoside F (2), and 3, 8-dimethyl- herbacetin-7-O-β-D-glucopyranoside (3), together with five known compounds (4-8), were isolated from the fresh needles of Pinus massoniana. Their structures were established by 1D, 2D NMR, HRMS and comparison with the literature dat...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1642331

    authors: Xiao YC,Shi ZF,Yan CQ,Tang QX,Zhao MX,Liu LT,Huang QS,Ye L,Xu K,Ke X

    更新日期:2020-08-01 00:00:00

  • Resolution and chiral recognition of muscone as well as actions on neural system.

    abstract::In this letter, (R)-muscone and (S)-muscone were prepared by optical resolution of dl-muscone using N,N'-dibenzyl-l-tartaramide or N,N'-dibenzyl-d-tartaramide, according to the method reported by Kunihiko Takabe. But we separated the diastereomers using EtOH instead of MeOH in the recrystallization step to get the goa...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.996141

    authors: Meng Y,Xiao Q,Bai JY,Xiao X,Zhang S,Zhu XY,Cheng GF,Yin DL

    更新日期:2014-12-01 00:00:00

  • Toxicokinetics and toxicity of potassium 2-(1-hydroxypentyl)-benzoate in beagle dogs.

    abstract::Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1302940

    authors: Li J,Wang XL,Wang AP,Xu SF,Jin HT

    更新日期:2017-04-01 00:00:00

  • Three new compounds from Dictamnus dasycarpus and their anti-inflammatory activities.

    abstract::Three new compounds (1-3), named dasycarine G (1), dasycarether (2), and dasycarester (3), along with seven known compounds (4-10) obtained from the genus Dictamnus for the first time, were isolated from the root bark of Dictamnus dasycarpus. Their structures were elucidated on the basis of spectroscopic data (UV, IR,...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1620213

    authors: Gao P,Wang L,Zhao L,Zhang C,Zeng KW,Zhao MB,Zhang QY,Jiang Y,Tu PF,Guo XY

    更新日期:2020-08-01 00:00:00

  • A pair of 24-hydroperoxyl epimeric dammarane saponins from flower-buds of Panax ginseng.

    abstract::Further investigation on the saponins of the flower-buds of Panax ginseng C. A. Meyer has resulted in the isolation and structural elucidation of a pair of new 24-epimers of dammarane type saponins named ginsenoside I and II. The structures of the epimers were characterized on the basis of chemical and spectral eviden...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020108041396

    authors: Qiu F,Ma ZZ,Xu SX,Yao XS,Che CT,Chen YJ

    更新日期:2001-01-01 00:00:00

  • Chemical constituents from Eupatorium chinense.

    abstract::Two new monoterpenoid glycosides, α-(E)-acaridiol 8-O-β-d-glucopyranoside (1) and α-(E)-acaridiol 9-O-β-d-glucopyranoside (2), as well as a new thiophen, 2-acetyl-3-hydroxy-5-(prop-1-ynyl)thiophen 3-O-β-d-glucopyranoside (3), were isolated from the roots of Eupatorium chinense. Their structures were determined on the ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.598149

    authors: Wang WJ,Wang Y,Zhang QW,Zhang XQ,Yang TT,Dai Y,Wang L,Zhang LH,Ye WC

    更新日期:2011-09-01 00:00:00

  • Antioxidant lignans from the seeds of Vitex negundo var. cannabifolia.

    abstract::A new phenyldihydronaphthalene-type lignan, vitexdoin F (1), along with 22 known lignan derivatives (2-23) was isolated from the seeds of Vitex negundo var. cannabifolia. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analyses. The antioxidant activities of these lignans were evaluated ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.929574

    authors: Lou ZH,Li HM,Gao LH,Li RT

    更新日期:2014-01-01 00:00:00

  • Effect of octadecanoyl acetal sodium sulphite series with different numbers of double bonds on their immunological and surface activities.

    abstract::The relationship between the immunological activities and their surface activities of octadecanoyl acetal sodium sulphite series containing different numbers of double bonds (HOU-C18:n; n = 1, Delta9; n = 2, Delta9,12; n = 3, Delta9,12,15) were studied. The results showed that HOU-C18:n were able to increase the carbo...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500289659

    authors: Yuan LJ,Ye XL,Li XG,He HM

    更新日期:2007-01-01 00:00:00

  • Novel acylkaempferol glycoside from the endemic species, Vernonia travancorica Hook. f.

    abstract::Vernonia travancorica Hook. f. is a taxon, endemic to the evergreen forests of Western Ghats (above 1000 m), India. From the aqueous EtOH extract of the air-dried corymbose inflorescence a novel secondary metabolite, 3-O-beta-[beta-(6'''-acetyl)-D-glucopyranosyl(1-->2)]-D-glucopyranosyl kaempferol (1), has been isolat...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000147401

    authors: Seetharaman TR,Petrus AJ

    更新日期:2004-12-01 00:00:00

  • Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity.

    abstract::Four new oleanane-type triterpenoid saponins, cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-xylopyranosyl-(1 --> 2)]-beta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranoside (1), cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-glucopyranosyl-(1 -->...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802144719

    authors: Wen P,Zhang XM,Yang Z,Wang NL,Yao XS

    更新日期:2008-09-01 00:00:00

  • Synthesis of (+)-lariciresinol 3a-acetate, a lignan from Aglaia elaeagnoidea.

    abstract::(+)-Lariciresinol 3a-acetate [(+)-(3S)-acetyloxymethyl-(2S)-(4-hydroxy-3-methoxyphenyl)-(4R)-[(4-hydroxy-3-methoxyphenyl)methyl]tetrahydrofuran] (1), a metabolite of A. elaeagnoidea was synthesized starting from (-)-lariciresinol (2) in three steps with an overall yield of 66%. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008039904

    authors: Rajasekhar D,Subbaraju GV

    更新日期:2000-01-01 00:00:00

  • Total synthesis and cyclization strategy of samoamide A, a cytotoxic cyclic octapeptide rich in proline and phenlalanine isolated from marine cyanobacterium.

    abstract::Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). The first total synthesis of samoamide A was achieved by employing a strategy of a s...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1450391

    authors: Chang Q,Li YL,Zhao X

    更新日期:2019-02-01 00:00:00

  • Two new steroidal glycosides from Cynanchum wallichii.

    abstract::Two new C21 steroidal glycosides were isolated from Cynanchum wallichii Wight. Their structures were elucidated as caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside (1) and caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-ole...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.915816

    authors: Wang D,Pan WH,Bao YR,Yang XX,Meng XS

    更新日期:2014-01-01 00:00:00

  • Two new dammarane-type triterpene saponins from red American ginseng.

    abstract::Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.550575

    authors: Liu JP,Lu D,Li PY

    更新日期:2011-03-01 00:00:00