Anti-tumor activities of andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF level.

abstract：:Chemical investigation on the cultures of Phellinus tuberculosus and Laetiporus sulphureus lead to the isolation of two new illudin-type sesquiterpenoids (phellinuin J and sulphureuine A). Their structures were elucidated by 1D, 2D NMR and MS spectroscopic data. These compounds were purposely evaluated for their cytot...

journal_title：Journal of Asian natural products research

authors： He JB,Tao J,Miao XS,Feng YP,Bu W,Dong ZJ,Li ZH,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

更新日期：2011-04-01 00:00:00

abstract：:A rare type of phenolic compound, namely, planchol E (1), was isolated from the cones and seeds of Pinus yunnanensis together with 16 known abietane diterpenoids (2-17). The structure of planchol E was established on the basis of extensive spectroscopic analysis, and it was found that the new compound did not show cyt...

journal_title：Journal of Asian natural products research

authors： Lei T,Li Y,Li DM,Liu GM,Liu JK,Wang F

更新日期：2011-05-01 00:00:00

abstract：:Two new xanthone O-glycosides, polyhongkongenosides A (1) and B (2), together with four known xanthone glycosides, were isolated from the herbs of Polygala hongkongensis Hemsl. Their structures were elucidated on the basis of UV, IR, NMR, and MS spectral data. The antioxidant in vitro activities of 1-6 were determined...

journal_title：Journal of Asian natural products research

authors： Wu JF,Chen SB,Gao JC,Song HL,Wu LJ,Chen SL,Tu PF

更新日期：2008-07-01 00:00:00

abstract：:A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

journal_title：Journal of Asian natural products research

authors： Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

更新日期：2018-05-01 00:00:00

abstract：:Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combination with chemical reactions. ...

journal_title：Journal of Asian natural products research

authors： Li HM,Wan DW,Li RT

更新日期：2015-01-01 00:00:00

abstract：:A new natural coumarin, angepubebisin (1), and a new furan, angepubefurin (2), together with the five known compounds, umbelliferone, angelol B (3), ulopterol (4), peucedanol (5), and scopoletin, were isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The structures of angepubebisin (1) an...

journal_title：Journal of Asian natural products research

authors： Yang XW,Zhang CY,Zhang BG,Lu Y,Luan JW,Zheng QT

更新日期：2009-08-01 00:00:00

abstract：:Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

journal_title：Journal of Asian natural products research

authors： Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

更新日期：2010-10-01 00:00:00

abstract：:Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3-9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1 and 2 possessed the potent anti-complement and anti-inflammatory activities. ...

journal_title：Journal of Asian natural products research

authors： Wang MY,Zhang Y,Zhang H,Feng XR,Li XB

更新日期：2019-06-01 00:00:00

abstract：:Mucor spinosus has been employed for the biotransformation of cinobufagin (1) to afford three metabolites. On the basis of their physico-chemical data, the structures of the transformation products have been characterized as 1beta-hydroxy-cinobufagin (2), 12beta-hydroxy-cinobufagin (3) and 1beta,12beta-dihydroxy-cinob...

journal_title：Journal of Asian natural products research

authors： Zhang W,Ye M,Qu GQ,Wu WY,Chen YJ,Guo DA

更新日期：2005-06-01 00:00:00

abstract：:Two new lignans, 9-salicyl-(+)-isolariciresinol (1) and gaultheroside G (2), together with seven known compounds, were isolated from the ethanolic extract of the whole plant of Gaultheria yunnanensis. Their structures were determined by extensive NMR and MS analyses. Gaultheroside G (2) was found to have an unusual et...

journal_title：Journal of Asian natural products research

authors： Gao YP,Shen YH,Xu XK,Tian JM,Zeng HW,Lin S,Liu CM,Zhang WD

更新日期：2014-01-01 00:00:00

abstract：:A new diterpenoid alkaloid, racemulotine (1), was isolated from the whole plants of Aconitum racemulosum Franch var. pengzhouense, and its structure was elucidated by 1D- and 2D-NMR spectra. ...

journal_title：Journal of Asian natural products research

authors： Peng CS,Jian XX,Wang FP

更新日期：2001-01-01 00:00:00

abstract：:In this paper, the structure-activity relationships of chemically modified uronic acid polymer fragments from brown algae with regard to their antioxidant effects on H2O2-damaged lymphocyte were studied. The results indicated that the most potent antioxidant activity was obtained from the sulfated polysaccharide with ...

journal_title：Journal of Asian natural products research

authors： Hu JF,Gen MY,Zhang JT,Jiang HD

更新日期：2001-01-01 00:00:00

abstract：:Three new acetylated anthraquinone glycosides (1-3) were isolated from the seed of Cassia obtusifolia, together with one parent anthraquinone glycoside (1a). Their structures were determined on the basis of spectroscopic methods and physicochemical properties as obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1)...

journal_title：Journal of Asian natural products research

authors： Wu XH,Cai JJ,Ruan JL,Lou JS,Duan HQ,Zhang J,Cheng CR,Guo DA,Wu ZY,Zhang YW

更新日期：2011-06-01 00:00:00

abstract：:Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

journal_title：Journal of Asian natural products research

authors： Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

更新日期：2009-06-01 00:00:00

abstract：:One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...

journal_title：Journal of Asian natural products research

authors： Zhang X,Liu F,Feng ZM,Jiang JS,Yang YN,Zhang PC

更新日期：2021-01-18 00:00:00

abstract：:Three new sesquiterpenoids (1-3), along with four known compounds (4-7), were isolated from cultures of the fungus Conocybe siliginea. The structures of new compounds were elucidated using spectroscopic methods. The known compounds were identified by comparing their spectroscopic data with those reported in the litera...

journal_title：Journal of Asian natural products research

authors： Yang XY,Li ZH,Dong ZJ,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extr...

journal_title：Journal of Asian natural products research

authors： Su SS,Tian L,Chen G,Li ZQ,Xu WF,Pei YH

更新日期：2013-01-01 00:00:00

abstract：:Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-...

journal_title：Journal of Asian natural products research

authors： Liu GL,Xu W,Liu XJ,Yan XL,Chen J

更新日期：2020-01-01 00:00:00

abstract：:(+)-Lariciresinol 3a-acetate [(+)-(3S)-acetyloxymethyl-(2S)-(4-hydroxy-3-methoxyphenyl)-(4R)-[(4-hydroxy-3-methoxyphenyl)methyl]tetrahydrofuran] (1), a metabolite of A. elaeagnoidea was synthesized starting from (-)-lariciresinol (2) in three steps with an overall yield of 66%. ...

journal_title：Journal of Asian natural products research

authors： Rajasekhar D,Subbaraju GV

更新日期：2000-01-01 00:00:00

abstract：:A new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2H)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin J (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol...

journal_title：Journal of Asian natural products research

authors： Wang LQ,Tang ZR,Mu WH,Kou JF,He DY

更新日期：2013-11-01 00:00:00

abstract：:Vernonia travancorica Hook. f. is a taxon, endemic to the evergreen forests of Western Ghats (above 1000 m), India. From the aqueous EtOH extract of the air-dried corymbose inflorescence a novel secondary metabolite, 3-O-beta-[beta-(6'''-acetyl)-D-glucopyranosyl(1-->2)]-D-glucopyranosyl kaempferol (1), has been isolat...

journal_title：Journal of Asian natural products research

authors： Seetharaman TR,Petrus AJ

更新日期：2004-12-01 00:00:00

abstract：:Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

journal_title：Journal of Asian natural products research

authors： Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

更新日期：2015-01-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:Barlericin, the new neolignan diglycoside, has been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with dehydrodiconiferyl alcohol 12-O-beta-D-glucopyranoside (2), reported for the first time from the genus Barleria. Their structures have been assigned on the basis of spectral studies. ...

journal_title：Journal of Asian natural products research

authors： Karim A,Noor AT,Malik A

更新日期：2010-08-01 00:00:00

abstract：:Two new sesquiterpene derivatives, (+)-8β-hydroxy-longicamphenylone (1) and 11β-hydroxy-13-isopropyl-dihydrodehydrocostus lactone (2), were isolated from Chinese eaglewood. Their structures were elucidated on the basis of spectroscopic analyses including HR-ESI-MS, (1)H and (13)C NMR, DEPT, (1)H-(1)H COSY, HSQC, HMBC,...

journal_title：Journal of Asian natural products research

authors： Yang L,Qiao LR,Zhang JJ,Dai JG,Guo SX

更新日期：2012-01-01 00:00:00

abstract：:We present in this paper the efficient four-component one-pot synthesis of a fully protected hexaarabinogalactan 2 with di-branched structure by using D-thiogalactopyranoside 3,6-diol 3 as the central glycosylating agent. After global deprotection, 2 was converted into the 3-aminopropyl linker-containing free oligosac...

journal_title：Journal of Asian natural products research

authors： Huang H,Han L,Lan YM,Zhang LL

更新日期：2014-01-01 00:00:00

abstract：:Carbazole alkaloids, 3-methylcarbazole (1), murrayafoline A (2), girinimbine (3), mahanimbine (4) and bicyclomahanimbine (5), were isolated for the first time from Clausena dunniana Levl. by bioassay-guided separation procedure and were identified by spectroscopic methods. Compounds 1-5 showed growth inhibitory activi...

journal_title：Journal of Asian natural products research

authors： Cui CB,Yan SY,Cai B,Yao XS

更新日期：2002-12-01 00:00:00

abstract：:Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...

journal_title：Journal of Asian natural products research

authors： Baloch IB,Baloch MK

更新日期：2010-07-01 00:00:00

abstract：:Tripterygium wilfordii Hook. f. is the traditional medicinal plants in China. Triptolide, wilforgine, and wilforine are the bioactive compounds in T. wilfordii. In this study, the contents of three metabolites and transcription levels of 21 genes involved in three metabolites biosynthesis in T. wilfordii were examined...

journal_title：Journal of Asian natural products research

authors： Zhang J,Huo YB,Liu Y,Feng JT,Ma ZQ,Zhu CS,Zhang X

更新日期：2017-08-01 00:00:00