The first total synthesis of anemarchalconyn and anemarcoumarin A.

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male...

journal_title：Journal of Asian natural products research

authors： Liu J,Hu G,Xu R,Qiao Y,Wu HP,Ding X,Duan P,Tu P,Lin YJ

更新日期：2013-07-01 00:00:00

abstract：:A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence. ...

journal_title：Journal of Asian natural products research

authors： Pei G,He GX,Du FL,Jiang DS

更新日期：2008-09-01 00:00:00

abstract：:Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

journal_title：Journal of Asian natural products research

authors： Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

更新日期：2006-12-01 00:00:00

abstract：:Three new alkaloids namely 8-(4-hydroxyphenyl)-6-methoxy-3,4-dihydroisoquinolin-1(2H)-one (1), 4-aminonigellidine (2), and N-[(4-hydroxy-2-isopropyl-5-methyl)]phenylurea (3), along with six known ones (4-9), were isolated from the seeds of Nigella glandulifera. The structures of 1-3 were determined through spectroscop...

journal_title：Journal of Asian natural products research

authors： Guo WH,Li XM,Huang SS,Yang MH,Kong LY

更新日期：2017-01-01 00:00:00

abstract：:A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

journal_title：Journal of Asian natural products research

authors： Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

更新日期：2007-04-01 00:00:00

abstract：:A new prenylated coumarin diglycoside, 6-prenylcoumarin-7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1) and five known flavonoid glycosides (2-6) were isolated from the leaves and stems of Clausena dunniana. The structures of these isolates were elucidated based on comprehensive MS, UV, IR, and NMR spectroscopic d...

journal_title：Journal of Asian natural products research

authors： Cao NK,Zhu SS,Chen YM,Ma XL,Zhao MB,Li J,Tu PF,Jiang Y

更新日期：2020-08-30 00:00:00

abstract：:A new diterpenoid, dehydrovibsanin G (1), a new lignan, (+)-9'-O-senecioyllariciresinol (2), and six known compounds (3-8) were isolated from the branches and leaves of Viburnum odoratissimum var. odoratissimum. The structures of these compounds were elucidated by analysis of spectroscopic data. Both new compounds sho...

journal_title：Journal of Asian natural products research

authors： Li FJ,Yu JH,Wang GC,Zhang H,Yue JM

更新日期：2015-05-01 00:00:00

abstract：:Five new indole alkaloid glucosides named isatindigotindolosides A-E (1-5), along with three known analogs (6-8), were isolated from an aqueous extract of the Isatis indigotica roots. Their structures including the absolute configurations were determined based on comprehensive spectroscopic data analysis, combined wit...

journal_title：Journal of Asian natural products research

authors： Liu YF,Chen MH,Lin S,Li YH,Zhang D,Jiang JD,Shi JG

更新日期：2016-01-01 00:00:00

abstract：:Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone derivatives have been...

journal_title：Journal of Asian natural products research

authors： Kumar GS,Tiwari AK,Rao VR,Prasad KR,Ali AZ,Babu KS

更新日期：2010-11-01 00:00:00

abstract：:The relationship between the immunological activities and their surface activities of octadecanoyl acetal sodium sulphite series containing different numbers of double bonds (HOU-C18:n; n = 1, Delta9; n = 2, Delta9,12; n = 3, Delta9,12,15) were studied. The results showed that HOU-C18:n were able to increase the carbo...

journal_title：Journal of Asian natural products research

authors： Yuan LJ,Ye XL,Li XG,He HM

更新日期：2007-01-01 00:00:00

abstract：:Three new eremophilane-type sesquiterpenoids, alashanoids K-M (1-3), and one known analogue (4) were isolated from the peeled stems of Syringa pinnatifolia. All the compounds were isolated from the genus Syringa for the first time. Structures of these compounds were established using 1D and 2D NMR and MS data. The abs...

journal_title：Journal of Asian natural products research

authors： Peng B,Zhang RF,Du BZ,Jiao SG,Zhou XC,Gao XL,Chen SY,Tu PF,Chai XY

更新日期：2019-12-01 00:00:00

abstract：:Two new (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates (7 and 8) were synthesized and evaluated for biological activity. Compound 8 showed highly potent anticancer activity against A-549 cell line with IC50 of 2.16 ± 1.02 μM, which displayed the highest selectivity index value (SI = 14.5) in A-54...

journal_title：Journal of Asian natural products research

authors： Zi CT,Yang L,Hu Y,Zhang P,Tang H,Zhang BL,Shen XJ,Kong QH,Wang Y,Wang XJ,Sheng J

更新日期：2020-07-03 00:00:00

abstract：:Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...

journal_title：Journal of Asian natural products research

authors： Ma X,Jiang L,Zhu MH,Liu CH,Wang GC,Li YT,Liu T,Li YJ

更新日期：2021-01-19 00:00:00

abstract：:Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataoside...

journal_title：Journal of Asian natural products research

authors： Yin YQ,Kong LY

更新日期：2008-03-01 00:00:00

abstract：:Carbazole alkaloids, 3-methylcarbazole (1), murrayafoline A (2), girinimbine (3), mahanimbine (4) and bicyclomahanimbine (5), were isolated for the first time from Clausena dunniana Levl. by bioassay-guided separation procedure and were identified by spectroscopic methods. Compounds 1-5 showed growth inhibitory activi...

journal_title：Journal of Asian natural products research

authors： Cui CB,Yan SY,Cai B,Yao XS

更新日期：2002-12-01 00:00:00

abstract：:Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

journal_title：Journal of Asian natural products research

authors： Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

更新日期：2005-10-01 00:00:00

abstract：:A new phenolic glycoside, 6'-[(E)-2''-hydroxymethyl, 2''-butenoyl] arbutin (1), and two known phenolic glycosides, 6'-[(E)-4''-hydroxycinnamoyl] arbutin (2) and 6'-[(E)-3'',4''-dihydroxycinnamoyl] arbutin (3), were isolated from the leaves of Heliciopsis lobata (Merr.) Sleum. Their structures were elucidated by variou...

journal_title：Journal of Asian natural products research

authors： He QQ,Liu MS,Jin DJ,Kong LY

更新日期：2006-06-01 00:00:00

abstract：:Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

journal_title：Journal of Asian natural products research

authors： Jing WY,Jiang C,Ji F,Hua HM,Li ZL

更新日期：2013-11-01 00:00:00

abstract：:Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

journal_title：Journal of Asian natural products research

authors： Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

更新日期：2010-12-01 00:00:00

abstract：:Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...

journal_title：Journal of Asian natural products research

authors： Zheng Q,Feng Y,Xu DS,Lin X,Chen YZ

更新日期：2009-01-01 00:00:00

abstract：:Mucor spinosus has been employed for the biotransformation of cinobufagin (1) to afford three metabolites. On the basis of their physico-chemical data, the structures of the transformation products have been characterized as 1beta-hydroxy-cinobufagin (2), 12beta-hydroxy-cinobufagin (3) and 1beta,12beta-dihydroxy-cinob...

journal_title：Journal of Asian natural products research

authors： Zhang W,Ye M,Qu GQ,Wu WY,Chen YJ,Guo DA

更新日期：2005-06-01 00:00:00

abstract：:Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

journal_title：Journal of Asian natural products research

authors： Mu LH,Li JB,Yang JZ,Zhang DM

更新日期：2007-09-01 00:00:00

abstract：:Two new drimane sesquiterpenoids, 11,12-dihydroxy-15-drimeneoic acid (1) and 3α,11,15-trihydroxydrimene (2), were isolated from cultures of the basidiomycete Agaricus arvensis, together with one known compound 3β,11,12-trihydroxydrimene (3). Their structures were established by means of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Ding JH,Li ZH,Dong ZJ,Feng T,Zhang HB,Liu JK

更新日期：2013-01-01 00:00:00

abstract：:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells an...

journal_title：Journal of Asian natural products research

authors： Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YH

更新日期：2009-09-01 00:00:00

abstract：:A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

journal_title：Journal of Asian natural products research

authors： Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

更新日期：2013-01-01 00:00:00

abstract：:Irritant and cytotoxic potentiality of six coumarins, isolated for the first time from the roots of Angelica glauca identified as 5,6,7-trimethoxycoumarin, 6-methoxy-7,8-methylenedioxycoumarin, bergapten, decursinol angelate, decursin, and nodakenetin, were investigated. The irritant potential was explored by open mou...

journal_title：Journal of Asian natural products research

authors： Saeed MA,Sabir AW

更新日期：2008-01-01 00:00:00

abstract：:Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoside (1) and 4-beta-D-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranosi...

journal_title：Journal of Asian natural products research

authors： Li FS,Dou DQ,Xu L,Chi XF,Kang TG,Kuang HX

更新日期：2009-07-01 00:00:00

abstract：:A new hTopo I isomerase inhibitor, (+)-3,3',7,7',8,8'-hexahydroxy-5,5'-dimethylbianthraquinone (2240A), was isolated from the mangrove endophytic fungus no. 2240 collected from an estuarine mangrove at the South China Sea coast. Its structure was elucidated by spectral analyses including two-dimensional NMR, HR-EI-MS,...

journal_title：Journal of Asian natural products research

authors： Tan N,Cai XL,Wang SY,Pan JH,Tao YW,She ZG,Zhou SN,Lin YC,Vrijmoed LL

更新日期：2008-07-01 00:00:00

abstract：:Three new polyoxypregnane glycosides, tenacigenosides F-H (1-3), were isolated from the stems of Marsdenia tenacissima. The structures of these new compounds were elucidated from 1D and 2D NMR spectra, as well as from HR-MS and acid hydrolysis. ...

journal_title：Journal of Asian natural products research

authors： Wang XL,Peng SL,Ding LS

更新日期：2010-08-01 00:00:00