Abstract:
:A new prenylated coumarin diglycoside, 6-prenylcoumarin-7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1) and five known flavonoid glycosides (2-6) were isolated from the leaves and stems of Clausena dunniana. The structures of these isolates were elucidated based on comprehensive MS, UV, IR, and NMR spectroscopic data analysis and comparison with the data reported in literature. Compounds 2-6 are obtained from the title plant for the first time. All these isolates were evaluated for their insulin-release promoting effects, and compounds 1, 2, and 4 exhibited significant activities (2.0 to 3.3-fold higher in comparison with the control, p < 0.01) at 40 μM.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Cao NK,Zhu SS,Chen YM,Ma XL,Zhao MB,Li J,Tu PF,Jiang Ydoi
10.1080/10286020.2020.1810671subject
Has Abstractpub_date
2020-08-30 00:00:00pages
1-7eissn
1028-6020issn
1477-2213pub_type
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