Three new alkaloids from the seeds of Nigella glandulifera.

Abstract:

:Three new alkaloids namely 8-(4-hydroxyphenyl)-6-methoxy-3,4-dihydroisoquinolin-1(2H)-one (1), 4-aminonigellidine (2), and N-[(4-hydroxy-2-isopropyl-5-methyl)]phenylurea (3), along with six known ones (4-9), were isolated from the seeds of Nigella glandulifera. The structures of 1-3 were determined through spectroscopic analyses (HRESIMS, 1D/2D NMR). Compound 1 was a rare isoquinolinone alkaloid with phenyl substituted at C-8.

journal_name

J Asian Nat Prod Res

authors

Guo WH,Li XM,Huang SS,Yang MH,Kong LY

doi

10.1080/10286020.2016.1184654

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

9-14

issue

1

eissn

1028-6020

issn

1477-2213

journal_volume

19

pub_type

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