Abstract:
:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells and caused a significant elevation of alkaline phosphatase activity, collagen content, and nodule mineralization in the cells (P < 0.05). Our data indicate that the enhancement of osteoblast function by 1 may be useful in the prevention of osteoporosis.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YHdoi
10.1080/10286020903117317subject
Has Abstractpub_date
2009-09-01 00:00:00pages
817-23issue
9eissn
1028-6020issn
1477-2213pii
914961157journal_volume
11pub_type
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