Synthesis, anti-oomycete activity, and SAR studies of paeonol derivatives.

abstract：:From the roots of Securidaca inappendiculata, one new sterol glycoside securisteroside (1) has been isolated, along with two known sterols, spinasterol (2) and 3-O-beta-D-glucopyranosyl-spinasterol (3). The new sterol was characterized by chemical and spectrometric methods, including EIMS, FABMS and one- and two-dimen...

journal_title：Journal of Asian natural products research

authors： Zhang LJ,Yang XD,Xu LZ,Zou ZM,Yang SL

更新日期：2005-08-01 00:00:00

abstract：:Dehydrozingerone analogs and related compounds were screened as potential antitumor promoters by using the in vitro short-term 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced Epstein-Barr virus early antigen activation assay. Among the 40 synthesized compounds, the prenylated analogs 16 and 34-36 showed the most si...

journal_title：Journal of Asian natural products research

authors： Tatsuzaki J,Nakagawa-Goto K,Tokuda H,Lee KH

更新日期：2010-03-01 00:00:00

abstract：:Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%. ...

journal_title：Journal of Asian natural products research

authors： Zhang JX,Li ZY,Wang YC,Ma WB,Hou M,Cao SH,Tang KH,Dong HB

更新日期：2017-09-01 00:00:00

abstract：:Two new drimane sesquiterpenoids, 11,12-dihydroxy-15-drimeneoic acid (1) and 3α,11,15-trihydroxydrimene (2), were isolated from cultures of the basidiomycete Agaricus arvensis, together with one known compound 3β,11,12-trihydroxydrimene (3). Their structures were established by means of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Ding JH,Li ZH,Dong ZJ,Feng T,Zhang HB,Liu JK

更新日期：2013-01-01 00:00:00

abstract：:A bioassay-guided phytochemical fractionation of the methanol extract of the Morus alba root barks led to the isolation of two chalcone-derived Diels-Alder adducts (1 and 2). Their structures were elucidated as kuwanon J 2,4,10″-trimethyl ether (1) and kuwanon R (2) by means of spectroscopic methods. Both compounds st...

journal_title：Journal of Asian natural products research

authors： Phung TX,Tran TH,Dan TT,Chau VM,Hoang TH,Nguyen TD

更新日期：2012-01-01 00:00:00

abstract：:Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

journal_title：Journal of Asian natural products research

authors： Liu JP,Lu D,Li PY

更新日期：2011-03-01 00:00:00

abstract：:A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

journal_title：Journal of Asian natural products research

authors： Kong LY,Zhi F

更新日期：2003-09-01 00:00:00

abstract：:By various chromatographic methods, one new phenylpropanoid, acanthopanic acid (1), and three known compounds, 1,2-O-dicaffeoylcyclopenta-3-ol (2), (4S)-α-terpineol 8-O-β-D-glucopyranoside (3), and rutin (4), were isolated from the methanol extract of the Acanthopanax koreanum leaves. Their structures were elucidated ...

journal_title：Journal of Asian natural products research

authors： Nhiem NX,Kim KC,Kim AD,Hyun JW,Kang HK,Van Kiem P,Van Minh C,Thu VK,Tai BH,Kim JA,Kim YH

更新日期：2011-01-01 00:00:00

abstract：:Four new lignan glycosides (1-4), named procumbenosides I, K, L, and M, together with cleistanthin B (5) reported for the first time in the genus Justicia, and 5 other known arylnaphthalene lignan glycosides (6-10) were isolated from the whole plant of Justicia procumbens. The structures of the new compounds were eluc...

journal_title：Journal of Asian natural products research

authors： Jin H,Yang S,Dong JX

更新日期：2017-01-01 00:00:00

abstract：:Four new minor taxanes (1-4) have been isolated from Ts-19 cell cultures of Taxus chinensis together with five known taxanes (5-9) by silica gel chromatography combined with semi-preparative HPLC chromatography. On the basis of the analyses of the chemical and spectroscopic (IR, MS, 1D, and 2D NMR) data, the structure...

journal_title：Journal of Asian natural products research

authors： Xie D,Jia HT,Zhang Y,Zou JH,Yin DL,Chen XG,Yan YN,Dai JG

更新日期：2009-06-01 00:00:00

abstract：:A new phenyldihydronaphthalene-type lignan, vitexdoin F (1), along with 22 known lignan derivatives (2-23) was isolated from the seeds of Vitex negundo var. cannabifolia. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analyses. The antioxidant activities of these lignans were evaluated ...

journal_title：Journal of Asian natural products research

authors： Lou ZH,Li HM,Gao LH,Li RT

更新日期：2014-01-01 00:00:00

abstract：:The relationship between the immunological activities and their surface activities of octadecanoyl acetal sodium sulphite series containing different numbers of double bonds (HOU-C18:n; n = 1, Delta9; n = 2, Delta9,12; n = 3, Delta9,12,15) were studied. The results showed that HOU-C18:n were able to increase the carbo...

journal_title：Journal of Asian natural products research

authors： Yuan LJ,Ye XL,Li XG,He HM

更新日期：2007-01-01 00:00:00

abstract：:A new amide alkaloid, N-(3',4',5'-trimethoxy-cis-cinnamoyl)pyrrolidine (1), named sarmentomicine was isolated from the ethanol extract of the leaves of Malayan Piper sarmentosum, together with two known phenylpropanoids. Their structures were elucidated on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Sim KM,Mak CN,Ho LP

更新日期：2009-08-01 00:00:00

abstract：:A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

journal_title：Journal of Asian natural products research

authors： Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

更新日期：2007-04-01 00:00:00

abstract：:Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12beta-acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by ...

journal_title：Journal of Asian natural products research

authors： Guan SH,Xia JM,Yang M,Wang XM,Liu X,Guo DA

更新日期：2008-07-01 00:00:00

abstract：:A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...

journal_title：Journal of Asian natural products research

authors： Shi JX,Li YH,Wang X,Qin YQ,Zhang CY,Zhang X,Li CR,An MQ,Li LR,Lu SH,Huang J

更新日期：2018-11-01 00:00:00

abstract：:Further investigation on the saponins of the flower-buds of Panax ginseng C. A. Meyer has resulted in the isolation and structural elucidation of a pair of new 24-epimers of dammarane type saponins named ginsenoside I and II. The structures of the epimers were characterized on the basis of chemical and spectral eviden...

journal_title：Journal of Asian natural products research

authors： Qiu F,Ma ZZ,Xu SX,Yao XS,Che CT,Chen YJ

更新日期：2001-01-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:A new diimide derivative, named (-)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthe...

journal_title：Journal of Asian natural products research

authors： Li CY,Ding WJ,Shao CL,She ZG,Lin YC

更新日期：2010-09-01 00:00:00

abstract：:Three new alkylated benzoquinones, 2-hydroxy-5-ethoxy-3-nonyl-1,4-benzoquinone (1), 5-O-butyl-embelin (2), and 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone (3), together with seven known analogues (4-10), were isolated from the stems and twigs of mangrove plant, Aegiceras corniculatum. Their structural elucida...

journal_title：Journal of Asian natural products research

authors： Li Y,Dong C,Xu MJ,Lin WH

更新日期：2020-02-01 00:00:00

abstract：:Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

journal_title：Journal of Asian natural products research

authors： Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

更新日期：2015-01-01 00:00:00

abstract：:A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence. ...

journal_title：Journal of Asian natural products research

authors： Pei G,He GX,Du FL,Jiang DS

更新日期：2008-09-01 00:00:00

abstract：:Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

journal_title：Journal of Asian natural products research

authors： Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

更新日期：2015-01-01 00:00:00

abstract：:From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

journal_title：Journal of Asian natural products research

authors： Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

更新日期：2012-01-01 00:00:00

abstract：:In this paper, the structure-activity relationships of chemically modified uronic acid polymer fragments from brown algae with regard to their antioxidant effects on H2O2-damaged lymphocyte were studied. The results indicated that the most potent antioxidant activity was obtained from the sulfated polysaccharide with ...

journal_title：Journal of Asian natural products research

authors： Hu JF,Gen MY,Zhang JT,Jiang HD

更新日期：2001-01-01 00:00:00

abstract：:Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataoside...

journal_title：Journal of Asian natural products research

authors： Yin YQ,Kong LY

更新日期：2008-03-01 00:00:00

abstract：:Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

journal_title：Journal of Asian natural products research

authors： Hua F,Shang S,Hu ZW

更新日期：2017-04-01 00:00:00

abstract：:A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...

journal_title：Journal of Asian natural products research

authors： Chai MY

更新日期：2020-03-01 00:00:00

abstract：:Phytochemical investigation of the roots of Arisaema jacquemontii led to the isolation of two new triterpenoids, which were characterized by NMR, IR, and MS spectra as 30-nor-lanost-5-ene-3beta-ol (1) and 30-norlanost-5-ene-3-one (2). ...

journal_title：Journal of Asian natural products research

authors： Jeelani S,Khuroo MA,Razadan TK

更新日期：2010-02-01 00:00:00

abstract：:Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

journal_title：Journal of Asian natural products research

authors： Li J,Wang XL,Wang AP,Xu SF,Jin HT

更新日期：2017-04-01 00:00:00