A new triterpenoid and a new glycoside from Pilea cavaleriei.

abstract：:Two new selaginellin derivatives selaginellin P (1) and selaginellin Q (2) were isolated from Selaginella tamariscina. The structures of 1 and 2 were established as 2,4'-dihydroxy-4-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene (1) and 2,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene (2) on the basis of spectroscopic m...

journal_title：Journal of Asian natural products research

authors： Xu KP,Li J,Zhu GZ,He XA,Li FS,Zou ZX,Tan LH,Cheng F,Tan GS

更新日期：2015-01-01 00:00:00

abstract：:Two new dammarane-type triterpenoid saponins, namely ginsenoside Rk6 (1) and ginsenoside-Rh22 (2), were isolated from notoginseng medicinal fungal substance. The structures of 1 and 2 were established as 3β,6α,12β,26-tetrahydroxydammar-20(21),24(25)(E)-diene-6-O-β-D-glucopyranoside and 3β,6α, 20(S)-trihydroxy-12(R),23...

journal_title：Journal of Asian natural products research

authors： Xu W,Liu X,Liu XL,Jia AL,Wang XW,Qiu ZD

更新日期：2016-12-01 00:00:00

abstract：:Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...

journal_title：Journal of Asian natural products research

authors： Ma X,Jiang L,Zhu MH,Liu CH,Wang GC,Li YT,Liu T,Li YJ

更新日期：2021-01-19 00:00:00

abstract：:Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

journal_title：Journal of Asian natural products research

authors： Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

更新日期：2005-10-01 00:00:00

abstract：:Enterovirus 71 (EV71) is the major causative agent of hand foot and mouth disease. And EV71 causes epidemics worldwide, particularly in the Asia-Pacific region. Unfortunately, currently there is no approved vaccine or antiviral drug for EV71-induced disease prevention and therapy. In screening for anti-EV71 candidates...

journal_title：Journal of Asian natural products research

authors： Wang HQ,Meng S,Li ZR,Peng ZG,Han YX,Guo SS,Cui XL,Li YH,Jiang JD

更新日期：2013-01-01 00:00:00

abstract：:A new hTopo I isomerase inhibitor, (+)-3,3',7,7',8,8'-hexahydroxy-5,5'-dimethylbianthraquinone (2240A), was isolated from the mangrove endophytic fungus no. 2240 collected from an estuarine mangrove at the South China Sea coast. Its structure was elucidated by spectral analyses including two-dimensional NMR, HR-EI-MS,...

journal_title：Journal of Asian natural products research

authors： Tan N,Cai XL,Wang SY,Pan JH,Tao YW,She ZG,Zhou SN,Lin YC,Vrijmoed LL

更新日期：2008-07-01 00:00:00

abstract：:A new sterol, stigmast-5-ene-3beta,17alpha-diol (1), together with six known compounds, stigmast-5-ene-3beta-yl formate (2), stigmast-5-ene-3beta,7alpha-diol (3), stigmast-5-ene-7alpha-methoxy-3beta-ol (4), stigmast-5-ene-3-one (5), 3beta-sitostanol (6), and 3beta-sitosterol (7), was isolated from the fruits of Syzygi...

journal_title：Journal of Asian natural products research

authors： Chumkaew P,Kato S,Chantrapromma K

更新日期：2010-05-01 00:00:00

abstract：:Phytochemical investigation of the roots of Arisaema jacquemontii led to the isolation of two new triterpenoids, which were characterized by NMR, IR, and MS spectra as 30-nor-lanost-5-ene-3beta-ol (1) and 30-norlanost-5-ene-3-one (2). ...

journal_title：Journal of Asian natural products research

authors： Jeelani S,Khuroo MA,Razadan TK

更新日期：2010-02-01 00:00:00

abstract：:The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male...

journal_title：Journal of Asian natural products research

authors： Liu J,Hu G,Xu R,Qiao Y,Wu HP,Ding X,Duan P,Tu P,Lin YJ

更新日期：2013-07-01 00:00:00

abstract：:Our goals were to examine the dual-directional regulation effects of resveratrol (1) in vitro by using MCF-7 cells (estradiol receptor-positive cells), study its mechanism of action, and give a systematical analysis of the regulatory networks of each related factor. An MTT test and growth curve showed that the prolife...

journal_title：Journal of Asian natural products research

authors： Wang YZ,Cao B,Li SX,Zang ZH,Zhang JZ,Chen H

更新日期：2009-01-01 00:00:00

abstract：:A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

更新日期：2013-01-01 00:00:00

abstract：:A new flavonoid glycoside, 5,7-dihydroxy-4'-methoxyflavone-7-O-[6-O-(4-O-acetyl-alpha-L-rhamnosyl)-3-O-beta-D-glucosyl]-6-O-acetyl-beta-D-glucoside and three known flavonoid glycosides, 5,7-dihydroxy-4-methoxyflavone-7-0-[6-0-(4-0-acetyl-alpha-L-rhamnosyl)]-beta-D-glucoside, 3,5,7, 4'-tetrahydroxyflavonol-3-O-beta-D-g...

journal_title：Journal of Asian natural products research

authors： Yu SC,Wu QL,Wang LW,Yang JS,Xiao PG

更新日期：1999-01-01 00:00:00

abstract：:Six new sesquiterpenes, 10-hydroxy-epiaplysin (1), 10-hydroxy-aplysin (2), 10-hydroxy-debromoepiaplysin (3), aplysin-9-ene (4), epiaplysinol (5) and debromoepiaplysinol (6), together with 13 known compounds (7-19), have been isolated from the red alga Laurencia tristicha. The structures of 1-6 were determined by spect...

journal_title：Journal of Asian natural products research

authors： Sun J,Shi DY,Li S,Wang SJ,Han LJ,Fan X,Yang YC,Shi JG

更新日期：2007-09-01 00:00:00

abstract：:A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...

journal_title：Journal of Asian natural products research

authors： Shi JX,Li YH,Wang X,Qin YQ,Zhang CY,Zhang X,Li CR,An MQ,Li LR,Lu SH,Huang J

更新日期：2018-11-01 00:00:00

abstract：:Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 →...

journal_title：Journal of Asian natural products research

authors： Zhang XT,Ma SW,Jiao HY,Zhang QW

更新日期：2012-01-01 00:00:00

abstract：:A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

journal_title：Journal of Asian natural products research

authors： Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

更新日期：2008-05-01 00:00:00

abstract：:We present in this paper the efficient four-component one-pot synthesis of a fully protected hexaarabinogalactan 2 with di-branched structure by using D-thiogalactopyranoside 3,6-diol 3 as the central glycosylating agent. After global deprotection, 2 was converted into the 3-aminopropyl linker-containing free oligosac...

journal_title：Journal of Asian natural products research

authors： Huang H,Han L,Lan YM,Zhang LL

更新日期：2014-01-01 00:00:00

abstract：:Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1-2) and three known analogs (3-5) including a new natural product (5). Their structures were determined on the...

journal_title：Journal of Asian natural products research

authors： Sun ZH,Liang FL,Chen YC,Liu HX,Li HH,Zhang WM

更新日期：2016-11-01 00:00:00

abstract：:Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...

journal_title：Journal of Asian natural products research

authors： Zheng Q,Feng Y,Xu DS,Lin X,Chen YZ

更新日期：2009-01-01 00:00:00

abstract：:One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...

journal_title：Journal of Asian natural products research

authors： Zhang X,Liu F,Feng ZM,Jiang JS,Yang YN,Zhang PC

更新日期：2021-01-18 00:00:00

abstract：:Two new 3,4-seco-lanostane-type triterpenes, named as 15α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1), 5α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid 3-methyl ester (2), and one new lanostane triterpene 15α-acetoxylhydroxytrametenolic acid (3) together with a known one versisponic aci...

journal_title：Journal of Asian natural products research

authors： Yin X,Li ZH,Li Y,Feng T,Liu JK

更新日期：2015-01-01 00:00:00

abstract：:A new phenanthraquinone, named bauhinione (1), has been isolated from Bauhinia variegata L., and its structure has been elucidated as 2,7-dimethoxy-3-methyl-9,10-dihydrophenanthrene-1,4-dione on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Zhao YY,Cui CB,Cai B,Han B,Sun QS

更新日期：2005-12-01 00:00:00

abstract：:A new selaginellin derivative, selaginellin M (1), together with one known compound, selaginellin E (2), was isolated from Selaginella pulvinata. The structure of the new compound was elucidated and named as (R,S)-4-((4'-hydroxy-4-((2-hydroxyethoxy)methyl))-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)me...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Liu GR,Long HP,Li J,Li FS,Zou ZX,Kuang JW,Xie X,Tan GS

更新日期：2011-10-01 00:00:00

abstract：:Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin-secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11'-methyl-oleosidyl-(7'-->6'')]-beta-D-glucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectro...

journal_title：Journal of Asian natural products research

authors： Xiao K,Song QH,Zhang SW,Xuan LJ

更新日期：2008-01-01 00:00:00

abstract：:Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory...

journal_title：Journal of Asian natural products research

authors： Jiang JS,Li FS,Feng ZM,Yang YN,Zhang PC

更新日期：2020-01-01 00:00:00

abstract：:A new p-coumaroylated santalane-type sesquiterpenoid, 8-p-coumaroyl-α-santalene (1), a new p-coumaroylated oplopanane-type sesquiterpenoid, 8-β-p-coumaroyl-oplopanone (2), and three known p-coumaroylated humulene-type sesquiterpenoids (3-5) were isolated from the ethanol extract of the whole herbs of Pilea cavaleriei....

journal_title：Journal of Asian natural products research

authors： Ren HC,Zhang J,Liang H

更新日期：2018-02-01 00:00:00

abstract：:The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be a new strategy for treating epilepsy. So far, no studies have shown whether the ...

journal_title：Journal of Asian natural products research

authors： Peng YC,Wang S,Zhang Y,Huang LJ,Wang XL,Peng Y

更新日期：2019-09-01 00:00:00

abstract：:Two new polyketides, 3,11-dihydroxy-6,8-dimethyldodecanoic acid (1) and trichopyrone B (2), together with two known polyketides, sorbicillin (3) and penicillone A (4), have been isolated from the cultures broth of the fungus Penicillium decumbens. Their structures were elucidated by extensive spectroscopic analysis. A...

journal_title：Journal of Asian natural products research

authors： Lin S,Wu YZ,Chen KY,Ye J,Yang XW,Zhang WD

更新日期：2018-05-01 00:00:00

abstract：:Two new (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates (7 and 8) were synthesized and evaluated for biological activity. Compound 8 showed highly potent anticancer activity against A-549 cell line with IC50 of 2.16 ± 1.02 μM, which displayed the highest selectivity index value (SI = 14.5) in A-54...

journal_title：Journal of Asian natural products research

authors： Zi CT,Yang L,Hu Y,Zhang P,Tang H,Zhang BL,Shen XJ,Kong QH,Wang Y,Wang XJ,Sheng J

更新日期：2020-07-03 00:00:00

abstract：:Two new sesquiterpene pyridine alkaloids, Chinese bittersweet alkaloid A (1) and Chinese bittersweet alkaloid B (2), together with five known compounds 3β- hydroxyolean-9(11),12-diene, β-sitosterol, 1β,2β,6α,15β-tetraacetoxy-8β,9α- dibenzoyloxy-β-dihydroagarofuran, angulatin A and angulatin J, were isolated from the r...

journal_title：Journal of Asian natural products research

authors： Chang X,Wang ZY,Chen X,Ma YN,Zhang HY,Zhao TZ

更新日期：2019-11-01 00:00:00