Two new furostanol glycosides from the fibrous root of Ophiopogon japonicus (Thunb.) Ker-Gawl.

Abstract:

:Two new furostanol glycosides, ophiopogonins H (1) and I (2), were isolated from the fibrous root of Ophiopogon japonicus. The structures of 1 and 2 were established as (25R)-26-[(O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-22α-hydroxyfurost-5-ene-3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside and (25R)-26-[(O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-20α-hydroxyfurost-5,22-diene-3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside on the basis of spectroscopic means including HR-ESI-MS, 1D and 2D NMR experiments.

journal_name

J Asian Nat Prod Res

authors

Duan CL,Ma XF,Jiang Y,Liu JX,Tu PF

doi

10.1080/10286020.2010.495332

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

745-51

issue

9

eissn

1028-6020

issn

1477-2213

pii

926837490

journal_volume

12

pub_type

杂志文章
  • Three new alkaloids from the seeds of Nigella glandulifera.

    abstract::Three new alkaloids namely 8-(4-hydroxyphenyl)-6-methoxy-3,4-dihydroisoquinolin-1(2H)-one (1), 4-aminonigellidine (2), and N-[(4-hydroxy-2-isopropyl-5-methyl)]phenylurea (3), along with six known ones (4-9), were isolated from the seeds of Nigella glandulifera. The structures of 1-3 were determined through spectroscop...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1184654

    authors: Guo WH,Li XM,Huang SS,Yang MH,Kong LY

    更新日期:2017-01-01 00:00:00

  • Two new compounds from Aconitum tanguticum.

    abstract::A phytochemical investigation on the whole plant of Aconitum tanguticum (Ranunculaceae) resulted in the isolation and characterization of two new phenylpropanoid glycosides (1 and 2). Their structures were elucidated as 4-hydroxyphenethoxy-8-O-β-d-[6-O-(4-O-β-d-glucopyranosyl)-sinapoyl]-glucopyranoside (1) and 3,4-dim...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.904292

    authors: Li YR,Xu L,Li C,Wang ZM,Yang LX

    更新日期:2014-01-01 00:00:00

  • Three new noroleanane-type triterpenes from the roots of Pfaffia glomerata.

    abstract::The Amaranthaceae plant, Pfaffia glomerata, which is so-called as Brazil ginseng, is widely distributed in South American countries. Three new noroleanane-type triterpenes and four known oleanane-type triterpenes were isolated from the roots of P. glomerata. Their structures were determined by spectroscopic methods in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1343820

    authors: Han YZ,Zhou Y,Zhang ZT,Niu SY,Liu XH,Jia XY

    更新日期:2018-05-01 00:00:00

  • New phenolic glycosides from Polygonum cuspidatum.

    abstract::Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1646730

    authors: Jiang JS,Li FS,Feng ZM,Yang YN,Zhang PC

    更新日期:2020-01-01 00:00:00

  • Antimicrobial acylphloroglucinols from the leaves of Rhodomyrtus tomentosa.

    abstract::Phytochemical study on the leaves of Rhodomyrtus tomentosa resulted in the isolation of fourteen compounds including a new acylphloroglucinol, named tomentosone C (1), and a new flavonol glycoside, namely myricetin-3,7,3'-trimethyl ether-5'-O-β-glucopyranoside (2). Their structures were characterized by spectral data ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1121997

    authors: Liu HX,Tan HB,Qiu SX

    更新日期:2016-06-01 00:00:00

  • Phenol esters and other constituents from the stem barks of Stereospermum acuminatissimum.

    abstract::A new ester, 2-(4'-hydroxyphenyl)ethyl dotriacontanoate (1), and a new inseparable mixture of octacosan-1,28-dioldiferulate and triacontan-1,30-dioldiferulate (2) were isolated from the stem barks of Stereospermum acuminatissimum, along with 24 known compounds including 4 triterpenoids, 11 anthraquinones, 2 lignans, 3...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.619182

    authors: Sob SV,Wabo HK,Tang CP,Tane P,Ngadjui BT,Ye Y

    更新日期:2011-12-01 00:00:00

  • A novel alkaloid from Huperzia crispate.

    abstract::A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802181448

    authors: Pei G,He GX,Du FL,Jiang DS

    更新日期:2008-09-01 00:00:00

  • Two new dammarane-type triterpene saponins from red American ginseng.

    abstract::Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.550575

    authors: Liu JP,Lu D,Li PY

    更新日期:2011-03-01 00:00:00

  • Hsp90β inhibitors prevent GLT-1 degradation but have no beneficial efficacy on absence epilepsy.

    abstract::The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be a new strategy for treating epilepsy. So far, no studies have shown whether the ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1530989

    authors: Peng YC,Wang S,Zhang Y,Huang LJ,Wang XL,Peng Y

    更新日期:2019-09-01 00:00:00

  • Chemical constituents from the stem barks of Garcinia multiflora.

    abstract::Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.819854

    authors: Jing WY,Jiang C,Ji F,Hua HM,Li ZL

    更新日期:2013-11-01 00:00:00

  • New alkaloids from a marine-derived fungus Neosartorya sp.HN-M-3.

    abstract::Two new indole alkaloids, tryptoquivalines R and S, have been isolated from a marine-derived fungus Neosartorya sp.HN-M-3. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR experiments. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.797895

    authors: Xu N,Cao Y,Wang L,Chen G,Pei YH

    更新日期:2013-07-01 00:00:00

  • Anti-hyperglycemic effect of 11-hydroxypalmatine, a palmatine derivative from Stephania glabra tubers.

    abstract::A palmatine derivative, named 11-hydroxypalmatine (4), has been isolated from the tubers of Stephania glabra, together with three known alkaloids, palmatine (1), dehydrocorydalmine (2), and stepharanine (3). The structures of the compounds were elucidated by means of spectroscopic analysis including 2D NMR experiments...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903117325

    authors: Semwal DK,Rawat U,Semwal R,Singh R,Singh GJ

    更新日期:2010-02-01 00:00:00

  • Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.

    abstract::A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1350653

    authors: Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

    更新日期:2018-05-01 00:00:00

  • Annonaceous acetogenins of the seeds from Annona muricata.

    abstract::Muricatenol (1) is a new C37 non-THF ring acetogenin with four hydroxyls and one isolated double bond in the long aliphatic chain. 2,4-cis-Gigantetrocinone (2) and 2,4-trans-gigantetrocinone (3) have been isolated as their acetates by preparative TLC. 2,4-trans-Isoannonacin-10-one (4) and 2,4-trans-isoannonacin (5) ha...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020108040366

    authors: Li DY,Yu JG,Zhu JX,Yu DL,Luo XZ,Sun L,Yang SL

    更新日期:2001-01-01 00:00:00

  • A new sesquiterpenoid metabolite from Psilocybe samuiensis.

    abstract::A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802435794

    authors: Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

    更新日期:2009-01-01 00:00:00

  • Two new furostanol saponins from Tribulus terrestris L.

    abstract::Two new furostanol saponins, tribufurosides B (1) and C (2), were isolated from the fruits of Tribulus terrestris L. With the help of chemical and spectral analyses (IR, MS, 1D NMR and 2D NMR), the structures of two new furostanol saponins were established as 26-O-beta-d-glucopyranosyl-(25S)-5alpha-furost-20(22)-en-2a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020801966575

    authors: Xu TH,Xu YJ,Xie SX,Zhao HF,Han D,Li Y,Niu JZ,Xu DM

    更新日期:2008-05-01 00:00:00

  • Four new compounds from the roots of Uvaria macrophylla.

    abstract::Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020412331286524

    authors: Wang S,Zhang PC,Chen RY,Dai SJ,Yu SS,Yu DQ

    更新日期:2005-10-01 00:00:00

  • Structural features of a polysaccharide from Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao.

    abstract::A polysaccharide Astragalus polysaccharide (APS) was obtained from the boiling water extract of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao. The results of gas chromatography (GC) indicated that APS consisted of l-rhamnose (l-Rha), d-xylose (d-Xyl), d-glucose (d-Glc), and d-galactose (d-Gal) in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.778832

    authors: Fu J,Huang L,Zhang H,Yang S,Chen S

    更新日期:2013-01-01 00:00:00

  • Four new koumine metabolites in rat liver microsomes.

    abstract::Four new metabolites M-1 [1,2,18,19-tetradehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-2 [1,2,4,21,18,19-hexadehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-3 [1,2,18,19-tetradehydro-4-demethyl-4-formaldehyde-3,17-epoxy-7,20(2H,19H)-cyclovobasan], and M-4 [1,2,4,21,18,19-hexadehydro-4-demethy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.742511

    authors: Zhang L,Du L,Lv WW,Zhao QC,Hua W,An Y,Guo T,Wu LJ

    更新日期:2013-01-01 00:00:00

  • Phytochemistry and insecticidal activity of Annona mucosa leaf extracts against Sitophilus zeamais and Prostephanus truncatus.

    abstract::A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using physical and spectroscopic methods. The compounds showed weak to moderate insecticidal activities agai...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1818726

    authors: Makenzi AM,Manguro LOA,Owuor PO

    更新日期:2020-09-15 00:00:00

  • Two new 2-phenylethylchromones from artificial agarwood by holing method.

    abstract::Two new 2-(2-phenylethyl)chromone derivatives (1-2) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by exte...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1860029

    authors: Xiang P,Zeng YB,Wang H,Kong FD,Chen HQ,Mei WL,Dai HF

    更新日期:2020-12-18 00:00:00

  • Two new metabolites from a soil fungus Curvularia affinis strain HS-FG-196.

    abstract::Two new metabolites, pyrenocine J (1) and pyrenochaetic acid D (2), together with two known metabolites, pyrenocine A (3) and pyrenochaetic acid A (4), were isolated from a soil fungus, Curvularia affinis strain HS-FG-196. Their structures were established by extensive spectroscopic analysis. Compound 1 showed cytotox...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.713351

    authors: Zhang H,Mao LL,Qian PT,Shan WG,Wang JD,Bai H

    更新日期:2012-01-01 00:00:00

  • Two new caffeoyl conjugation from Erigeron breviscapus.

    abstract::Two new constituents with a novel basic skeleton were isolated from Erigeron breviscapus. On the basis of chemical and spectroscopic evidences, the structures of the new compounds were elucidated as 1R,3R-dihydroxy-4S,5R-dicaffeoyloxy cyclohexane carboxylic acid methyl ester (V), 1,4-dihydroxy-3R,5R-dicaffeoyloxy cycl...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008041367

    authors: Zhang WD,Tam HT,Chen WS,Kong DY,Li HT,Wang YH,Fouraste I

    更新日期:2000-01-01 00:00:00

  • Bromophenols from the brown alga Leathesia nana.

    abstract::Two new bromophenols, (E)-3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methylpropenal (1) and 3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methyl-1-propanol (2), together with 11 known bromophenols (3-13), were isolated from the ethanolic extract of the brown alga Leathesia nana S. et G. Their structures have been elucidated by spe...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001653273

    authors: Xu XL,Fan X,Song FH,Zhao JL,Han LJ,Yang YC,Shi JG

    更新日期:2004-09-01 00:00:00

  • A new diterpenoid from the leaves of Platycladus orientalis.

    abstract::A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1373102

    authors: Shi JX,Li YH,Wang X,Qin YQ,Zhang CY,Zhang X,Li CR,An MQ,Li LR,Lu SH,Huang J

    更新日期:2018-11-01 00:00:00

  • Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi).

    abstract::Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin-secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11'-methyl-oleosidyl-(7'-->6'')]-beta-D-glucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectro...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701394514

    authors: Xiao K,Song QH,Zhang SW,Xuan LJ

    更新日期:2008-01-01 00:00:00

  • Anticancer agents from marine sponges.

    abstract::Marine sponges are currently one of the richest sources of anticancer active compounds found in the marine ecosystems. More than 5300 different known metabolites are from sponges and their associated microorganisms. To survive in the complicated marine environment, most of the sponge species have evolved chemical mean...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章,评审

    doi:10.1080/10286020.2014.970535

    authors: Ye J,Zhou F,Al-Kareef AM,Wang H

    更新日期:2015-01-01 00:00:00

  • Thiophenes from Echinops latifolius.

    abstract::Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2'-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2'...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500176724

    authors: Wang Y,Li X,Meng DL,Li ZL,Zhang P,Xu J

    更新日期:2006-10-01 00:00:00

  • An in vitro study of the structure-activity relationships of sulfated polysaccharide from brown algae to its antioxidant effect.

    abstract::In this paper, the structure-activity relationships of chemically modified uronic acid polymer fragments from brown algae with regard to their antioxidant effects on H2O2-damaged lymphocyte were studied. The results indicated that the most potent antioxidant activity was obtained from the sulfated polysaccharide with ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020108040376

    authors: Hu JF,Gen MY,Zhang JT,Jiang HD

    更新日期:2001-01-01 00:00:00

  • Stemoninine-type alkaloids from the roots of Stemona sessilifolia.

    abstract::Two new stemoninine-type alkaloids, stemoninine A (1) and B (2), along with two known Stemona alkaloids, bisdehydrostemoninine (3) and bisdehydrostemoninine A (4), were isolated from the roots of Stemona sessilifolia, and their structures and relative configurations were determined on the basis of spectrometric data a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701833511

    authors: Wang P,Liu AL,Li ZH,Du GH,Qin HL

    更新日期:2008-03-01 00:00:00