Causes and risk factors for singleton stillbirth in Japan: Analysis of a nationwide perinatal database, 2013-2014.

abstract：:Argininosuccinate synthetase 1 (ASS1) is the key enzyme that controls biosynthesis of arginine (Arg). ASS1 is silenced in many human malignancies therefore, these tumors require extracellular Arg for growth. The Arg-degrading recombinant protein, pegylated arginine deiminase (ADI-PEG20), has been in clinical trials fo...

journal_title：Scientific reports

authors： Tsai WB,Long Y,Chang JT,Savaraj N,Feun LG,Jung M,Chen HHW,Kuo MT

更新日期：2017-09-07 00:00:00

abstract：:The Alzheimer's disease pathology is associated with accumulation of intracellular neurofibrillary tangles and extracellular senile plaques. The formation of initial nucleus triggers conformational changes in Tau and leads to its deposition. Hence, there is a need to eliminate these toxic proteins for proper functioni...

journal_title：Scientific reports

authors： Gorantla NV,Das R,Chidambaram H,Dubey T,Mulani FA,Thulasiram HV,Chinnathambi S

更新日期：2020-03-04 00:00:00

abstract：:Solid oxide fuel cells (SOFCs) are promising electrochemical devices that enable the highest fuel-to-electricity conversion efficiencies under high operating temperatures. The concept of multi-stage electrochemical oxidation using SOFCs has been proposed and studied over the past several decades for further improving ...

journal_title：Scientific reports

authors： Matsuzaki Y,Tachikawa Y,Somekawa T,Hatae T,Matsumoto H,Taniguchi S,Sasaki K

更新日期：2015-07-28 00:00:00

abstract：:Science, being a social enterprise, is subject to fragmentation into groups that focus on specialized areas or topics. Often new advances occur through cross-fertilization of ideas between sub-fields that otherwise have little overlap as they study dissimilar phenomena using different techniques. Thus to explore the n...

journal_title：Scientific reports

authors： Pan RK,Sinha S,Kaski K,Saramäki J

更新日期：2012-01-01 00:00:00

abstract：:An inexpensive and compact frequency multi-mode diode laser enables a compact two-photon polarization entanglement source via the continuous wave broadband pumped spontaneous parametric down-conversion (SPDC) process. Entanglement degradation caused by polarization mode dispersion (PMD) is one of the critical issues i...

journal_title：Scientific reports

authors： Lim HT,Hong KH,Kim YH

更新日期：2016-05-13 00:00:00

abstract：:The pathogenesis of glioblastoma (GBM) is characterized by highly invasive behavior allowing dissemination and progression. A conclusive image of the invasive process is not available. The aim of this work was to study invasion dynamics in GBM using an innovative in vivo imaging approach. Primary brain tumor initiatin...

journal_title：Scientific reports

authors： Alieva M,Leidgens V,Riemenschneider MJ,Klein CA,Hau P,van Rheenen J

更新日期：2019-02-14 00:00:00

abstract：:Fire blight, caused by the enterobacterium Erwinia amylovora, is a destructive disease, which can affect most members of the Rosaceae family. Since no significant genomic differences have been found by others to explain differences in virulence, we used here a gel-based proteomic approach to elucidate mechanisms and k...

journal_title：Scientific reports

authors： Holtappels M,Noben JP,Van Dijck P,Valcke R

更新日期：2018-08-03 00:00:00

abstract：:Despite major advances in targeted melanoma therapies, drug resistance limits their efficacy. Long noncoding RNAs (lncRNAs) are transcriptome elements that do not encode proteins but are important regulatory molecules. LncRNAs have been implicated in cancer development and response to different therapeutics and are th...

journal_title：Scientific reports

authors： Sanlorenzo M,Vujic I,Esteve-Puig R,Lai K,Vujic M,Lin K,Posch C,Dimon M,Moy A,Zekhtser M,Johnston K,Gho D,Ho W,Gajjala A,Oses Prieto J,Burlingame A,Daud A,Rappersberger K,Ortiz-Urda S

更新日期：2018-07-19 00:00:00

abstract：:Understanding the molecular mechanisms underlying Alzheimer's disease (AD) is necessary for the diagnosis and treatment of this neurodegenerative disorder. It is therefore important to detect the most important genes and miRNAs, which are associated with molecular events, and studying their interactions for recognitio...

journal_title：Scientific reports

authors： Moradifard S,Hoseinbeyki M,Ganji SM,Minuchehr Z

更新日期：2018-03-19 00:00:00

abstract：:In this study, we measured the human epidermal growth factor receptor 2 (HER2) copy number in both tissue and plasma samples of gastric cancer patients by using droplet digital polymerase chain reaction (ddPCR) method. Eighty gastric cancer patients were enrolled and both formalin-fixed and paraffin-embedded tissue an...

journal_title：Scientific reports

authors： Kim B,Nam SK,Seo SH,Park KU,Ahn SH,Park DJ,Kim HH,Kim WH,Lee HS

更新日期：2020-03-06 00:00:00

abstract：:We introduce an experimental method based upon a glass micropipette microinjection technique for generating a multitude of interconnected vesicles (IVs) in the interior of a single giant unilamellar phospholipid vesicle (GUV) serving as a cell model system. The GUV membrane, consisting of a mixture of soybean polar li...

journal_title：Scientific reports

authors： Ali Doosti B,Fjällborg D,Kustanovich K,Jesorka A,Cans AS,Lobovkina T

更新日期：2020-08-20 00:00:00

abstract：:An investigation was carried out to assess the effect of the P content on the microstructure and mechanical properties of ZCuPb20Sn5 alloy. Alloys of various compositions, (0.05, 0.1, 0.2, 0.3, 0.5% wt.% P) were melted in a melting furnace under 1200 °C and cast into metal mould, the hardness, strength and elongation ...

journal_title：Scientific reports

authors： Ren XY,Zhang X,Hong X,Ren J

更新日期：2019-09-16 00:00:00

abstract：:Myositis is characterised by muscle inflammation and weakness. Although generally thought to be driven by a systemic autoimmune response, increasing evidence suggests that intrinsic changes in the muscle might also contribute to the pathogenesis. Long non-coding RNAs (lncRNAs) are a family of novel genes that regulate...

journal_title：Scientific reports

authors： Hamann PD,Roux BT,Heward JA,Love S,McHugh NJ,Jones SW,Lindsay MA

更新日期：2017-08-14 00:00:00

abstract：:Significant aggregation between ZnO nanoparticles (ZnO NPs) dispersed in polar and nonpolar solvents hinders the formation of high quality thin film for the device application and impedes their excellent electron transporting ability. Herein a bifunctional coordination complex, titanium diisopropoxide bis(acetylaceton...

journal_title：Scientific reports

authors： Lee W,Yeop J,Heo J,Yoon YJ,Park SY,Jeong J,Shin YS,Kim JW,An NG,Kim DS,Park J,Kim JY

更新日期：2020-10-22 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been widely deployed in low-resource settings. These tests are typically read by visual inspection, and accurate record keeping and data aggregation remains a substantial challenge. A successful malaria elimination campaign will require new strategies that maximize the sensitivity of...

journal_title：Scientific reports

authors： Scherr TF,Gupta S,Wright DW,Haselton FR

更新日期：2016-06-27 00:00:00

abstract：:Liver disease is a leading cause of morbidity and mortality worldwide. Recently, the liver non-parenchymal cells have gained increasing attention for their potential role in the development of liver disease. Liver sinusoidal endothelial cells (LSECs), a specialized type of endothelial cells that have unique morphology...

journal_title：Scientific reports

authors： Mönkemöller V,Mao H,Hübner W,Dumitriu G,Heimann P,Levy G,Huser T,Kaltschmidt B,Kaltschmidt C,Øie CI

更新日期：2018-10-02 00:00:00

abstract：:Gamma-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is an activatable fluorescent probe that can be activated by γ-glutamyltranspeptidase (GGT). The expression of GGT in the kidney, which is one of the major organs exhibiting enhanced GGT expression, is exclusively localised to the cortex. Here, we aimed to inves...

journal_title：Scientific reports

authors： Iyama T,Takata T,Yamada K,Mae Y,Taniguchi S,Ida A,Ogawa M,Yamamoto M,Hamada S,Fukuda S,Kanda T,Sugihara T,Isomoto H,Urano Y

更新日期：2020-07-21 00:00:00

abstract：:Regret results from comparing non-optimal outcomes containing both gain and loss parts to better alternatives during decision-making. The present fMRI study aimed to explore whether levels of regret could change when gain or loss part of a non-optimal outcome was focused during a sequential risk taking task, i.e. the ...

journal_title：Scientific reports

authors： Liu Z,Li L,Zheng L,Xu M,Zhou FA,Guo X

更新日期：2017-02-01 00:00:00

abstract：:Directional transport of auxin is essential for plant development, with PIN auxin transport proteins representing an integral part of the machinery that controls hormone distribution. However, unlike the rapidly emerging framework of molecular determinants regulating PIN protein abundance and subcellular localization,...

journal_title：Scientific reports

authors： Benjamins R,Barbez E,Ortbauer M,Terpstra I,Lucyshyn D,Moulinier-Anzola J,Khan MA,Leitner J,Malenica N,Butt H,Korbei B,Scheres B,Kleine-Vehn J,Luschnig C

更新日期：2016-08-24 00:00:00

abstract：:There is emerging evidence that microRNAs (miRNAs) dysregulation is involved in the genesis and the progression of Prostate Cancer (PCa), thus potentially increasing their use in urological clinical practice. This is the first pilot study which utilizes Illumina Deep Sequencing to examine the entire miRNAs spectrum ex...

journal_title：Scientific reports

authors： Guelfi G,Cochetti G,Stefanetti V,Zampini D,Diverio S,Boni A,Mearini E

更新日期：2018-05-08 00:00:00

abstract：:As the global prevalence of childhood obesity continues to rise, researchers and clinicians have sought to develop more effective and personalized intervention techniques. In doing so, obesity interventions have expanded beyond the traditional context of nutrition to address several facets of a child's life, including...

journal_title：Scientific reports

authors： Feldman K,Solymos GMB,de Albuquerque MP,Chawla NV

更新日期：2019-12-11 00:00:00

abstract：:Tetrastatin, a 230 amino acid sequence from collagen IV, was previously demonstrated to inhibit melanoma progression. In the present paper, we identified the minimal active sequence (QKISRCQVCVKYS: QS-13) that reproduced the anti-tumor effects of whole Tetrastatin in vivo and in vitro on melanoma cell proliferation, m...

journal_title：Scientific reports

authors： Lambert E,Fuselier E,Ramont L,Brassart B,Dukic S,Oudart JB,Dupont-Deshorgue A,Sellier C,Machado C,Dauchez M,Monboisse JC,Maquart FX,Baud S,Brassart-Pasco S

更新日期：2018-06-29 00:00:00

abstract：:In the cricket Gryllus bimaculatus, flying occurs soon after the last imaginal molt and precedes the mating behavior in natural conditions. Here, we tested the hypothesis that flying may improve subsequent behavioral performance in a novel environment in female crickets. We developed a behavioral set-up to test female...

journal_title：Scientific reports

authors： Mezheritskiy M,Vorontsov D,Lapshin D,Dyakonova V

更新日期：2020-12-18 00:00:00

abstract：:The antioxidant and multiple organ protection effects of acid- extracted mycelia polysaccharides (Ac-MPS) from Pleurotus eryngii var. tuoliensis on HFE-induced hypertriglyceridemic mice were investigated. The results showed that Ac-MPS have potential ability to relieve the hypertriglyceridemia and preventing oxidative...

journal_title：Scientific reports

authors： Gao Z,Lai Q,Yang Q,Xu N,Liu W,Zhao F,Liu X,Zhang C,Zhang J,Jia L

更新日期：2018-11-30 00:00:00

abstract：:Heterocyclic amines (HCAs) are formed by cooking protein-rich foods, for instance, meat and fish, and are listed as possible human carcinogens. In the present study, the presence of five potential HCAs (IQ, MeIQ, MeIQx, 4,8-DiMeIQx, and PhIP) in cooked camel meat burgers was analyzed for the first time. The analysis w...

journal_title：Scientific reports

authors： Rizwan Khan M,Naushad M,Abdullah Alothman Z

更新日期：2017-05-10 00:00:00

abstract：:Light-inducible gene regulation has great potential for remote and noninvasive control of the fate and function of target cells. One method to achieve such control is delivery of heat shock protein (HSP) promoter-driven protein expression vectors and photothermal heaters into the cells, followed by activation by illum...

journal_title：Scientific reports

authors： Nakatsuji H,Kawabata Galbraith K,Kurisu J,Imahori H,Murakami T,Kengaku M

更新日期：2017-07-05 00:00:00

abstract：:High Refractive Index (HRI) dielectric nanoparticles have been proposed as an alternative to metallic ones due to their low absorption and magnetodielectric response in the VIS and NIR ranges. For the latter, important scattering directionality effects can be obtained. Also, systems constituted by dimers of HRI dielec...

journal_title：Scientific reports

authors： Barreda ÁI,Gutiérrez Y,Sanz JM,González F,Moreno F

更新日期：2017-09-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xu X,Zhao J,Wang M,Wang L,Yang J

更新日期：2020-02-06 00:00:00

abstract：:A spontaneous exchange bias (SEB) discovered by Wang et al. [Phys. Rev. Lett. 106 (2011) 077203.] after zero-field cooling (ZFC) has attracted recent attention due to its interesting physics. In this letter, we report a giant SEB tuned by Sb-doping in Ni50Mn38Ga12-xSbx Heusler alloys. Such an SEB was switched on below...

journal_title：Scientific reports

authors： Tian F,Cao K,Zhang Y,Zeng Y,Zhang R,Chang T,Zhou C,Xu M,Song X,Yang S

更新日期：2016-08-01 00:00:00

abstract：:Membrane protein oligomerization mediates a wide range of biological events including signal transduction, viral infection and membrane curvature induction. However, the relative contributions of protein-protein and protein-membrane interactions to protein oligomerization remain poorly understood. Here, we used the Ca...

journal_title：Scientific reports

authors： Tao M,Isas JM,Langen R

更新日期：2020-03-24 00:00:00