Primary rat LSECs preserve their characteristic phenotype after cryopreservation.

abstract：:The 6SA-CASSCF(10, 10)/6-31G (d, p) quantum chemistry method has been applied to perform on-the-fly trajectory surface hopping simulation with global switching algorithm and to explore excited-state intramolecular proton transfer reactions for the o-nitrophenol molecule within low-lying electronic singlet states (S0 a...

journal_title：Scientific reports

authors： Xu C,Yu L,Zhu C,Yu J,Cao Z

更新日期：2016-05-25 00:00:00

abstract：:When exploited as cell factories, Saccharomyces cerevisiae cells are exposed to harsh environmental stresses impairing titer, yield and productivity of the fermentative processes. The development of robust strains therefore represents a pivotal challenge for the implementation of cost-effective bioprocesses. Altering ...

journal_title：Scientific reports

authors： Martani F,Marano F,Bertacchi S,Porro D,Branduardi P

更新日期：2015-12-14 00:00:00

abstract：:Silver has long been employed as an electrically conductive component, and morphology-dependent properties have been actively investigated. Here we present a novel scalable synthesis method of flower-shaped silver nanoparticles (silver nanoflowers, Ag NFs). The preferential affinity of citrate molecules on (111) surfa...

journal_title：Scientific reports

authors： C MA,K P F,Singh S,Baik S

更新日期：2016-10-07 00:00:00

abstract：:Peritrichously-flagellated bacteria, such as Escherichia coli, self-propel in fluids by using specialised motors to rotate multiple helical filaments. The rotation of each motor is transmitted to a short flexible segment called the hook which in turn transmits it to a flagellar filament, enabling swimming of the whole...

journal_title：Scientific reports

authors： Riley EE,Das D,Lauga E

更新日期：2018-07-16 00:00:00

abstract：:This study aimed to determine whether formyl peptide receptors (FPRs) regulated the differentiation of neural stem cells (NSCs). FPRs promote the migration of NSCs both in vitro and in vivo. However, the role of FPRs during differentiation of NSCs is unknown. Analysis by Western blot showed significantly increased exp...

journal_title：Scientific reports

authors： Zhang L,Wang G,Chen X,Xue X,Guo Q,Liu M,Zhao J

更新日期：2017-03-16 00:00:00

abstract：:To determine the effects of the estrogen-related receptor γ (ESRRG) rs1890552 A > G polymorphism on dietary advice-mediated changes in fasting glucose and arterial stiffness, 374 subjects with normal fasting glucose (NFG; control group, no treatment) and 142 subjects with impaired fasting glucose (IFG group, dietary a...

journal_title：Scientific reports

authors： Kim M,Yoo HJ,Kim M,Seo H,Chae JS,Lee SH,Lee JH

更新日期：2017-08-29 00:00:00

abstract：:This study examines the analytical and numerical solution of electromagnetic surface waves supported by a resistive metasurface-covered grounded metamaterial structure. To simulate the metamaterial, the Kramers-Kronig relation based on the causality principle is used, while the modeling of the resistive metasurface ha...

journal_title：Scientific reports

authors： Yaqoob MZ,Ghaffar A,Alkanhal MAS,Naz MY,Alqahtani AH,Khan Y

更新日期：2020-09-23 00:00:00

abstract：:Uterus transplantation (UTx) is a potential option for women with uterine factor infertility to have a child. The clinical features indicating irreversible rejection of the uterus are unknown. In our experimental series of allogeneic UTx in cynomolgus macaques, six female macaques were retrospectively examined, which ...

journal_title：Scientific reports

authors： Kisu I,Emoto K,Masugi Y,Yamada Y,Matsubara K,Obara H,Matoba Y,Banno K,Kato Y,Saiki Y,Itagaki I,Kawamoto I,Iwatani C,Murase M,Nakagawa T,Tsuchiya H,Ishigaki H,Urano H,Ema M,Ogasawara K,Aoki D,Nakagawa K,Shiina

更新日期：2020-08-17 00:00:00

abstract：:The inconsistent findings on the association between COMT (catecholamine-O-methyl-transferase) and suicidal behaviour gave reason to choose a clear phenotype description of suicidal behaviour and take childhood maltreatment as environmental factor into account. The aim of this candidate-gene-association study was to e...

journal_title：Scientific reports

authors： Bernegger A,Kienesberger K,Carlberg L,Swoboda P,Ludwig B,Koller R,Inaner M,Zotter M,Kapusta N,Aigner M,Haslacher H,Kasper S,Schosser A

更新日期：2018-01-12 00:00:00

abstract：:There are approximately 1 million cryptococcal infections per year among HIV+ individuals, resulting in nearly 625,000 deaths. Cryptococcus neoformans and Cryptococcus gattii are the two most common species that cause human cryptococcosis. These two species of Cryptococcus have differences in pathogenicity, diagnosis,...

journal_title：Scientific reports

authors： Hu S,Gu F,Chen M,Wang C,Li J,Yang J,Wang G,Zhou Z,Yang Y

更新日期：2020-07-27 00:00:00

abstract：:Silicene is an exciting two-dimensional material that shares many of graphene's electronic properties, but differs in its structural buckling. This buckling allows opening a bandgap in silicene through the application of a perpendicular electric field. Here we show that this buckling also enables highly effective modu...

journal_title：Scientific reports

authors： Al-Dirini F,Hossain FM,Mohammed MA,Nirmalathas A,Skafidas E

更新日期：2015-10-06 00:00:00

abstract：:The corneal endothelium is essential for maintaining corneal transparency; therefore, corneal endothelial dysfunction causes serious vision loss. Tissue engineering-based therapy is potentially a less invasive and more effective therapeutic modality. We recently started a first-in-man clinical trial of cell-based ther...

journal_title：Scientific reports

authors： Okumura N,Kusakabe A,Hirano H,Inoue R,Okazaki Y,Nakano S,Kinoshita S,Koizumi N

更新日期：2015-10-07 00:00:00

abstract：:Astragalus membranaceus (HUANG QI, HQ) is a kind of traditional Chinese medicine. Researchers have widely concerned its antitumor effect. At present, there is still a lack of research on the treatment of laryngeal cancer with HQ. In this study, we integrated data from the weighted gene co-expression network of larynge...

journal_title：Scientific reports

authors： Dong KF,Huo MQ,Sun HY,Li TK,Li D

更新日期：2020-07-07 00:00:00

abstract：:The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades. Here, we investigated the role...

journal_title：Scientific reports

authors： Shi Y,Lai X,Ye L,Chen K,Cao Z,Gong W,Jin L,Wang C,Liu M,Liao Y,Wang JM,Zhou N

更新日期：2017-02-10 00:00:00

abstract：:Understanding and manipulating the dynamic properties of the magnetic vortices stabilized in patterned ferromagnetic structures are of great interest owing to the superior resonant features with the high thermal stability and their flexible tunability. So far, numerous methods for investigating the dynamic properties ...

journal_title：Scientific reports

authors： Cui X,Hu S,Hidegara M,Yakata S,Kimura T

更新日期：2015-12-09 00:00:00

abstract：:The endoplasmic reticulum (ER) is the main site of protein synthesis in eukaryotic cells and requires a high concentration of luminal chaperones to function. During protein synthesis, ER luminal chaperones are swept along the secretory pathway and must be retrieved to maintain cell viability. ER protein retrieval is a...

journal_title：Scientific reports

authors： Wu Z,Newstead S,Biggin PC

更新日期：2020-10-09 00:00:00

abstract：:To determine the association of birth weight (BW) and waist circumference (WC) on cardiovascular disease (CVD). The longitudinal cohort study consisted of 745 participants who were able to provide their birth weight information and were followed from 2002 to 2014. During the follow-up, 83 events of CVD were confirmed....

journal_title：Scientific reports

authors： Tian J,Qiu M,Li Y,Zhang X,Wang H,Sun S,Sharp NS,Tong W,Zeng H,Zheng S,Song X,Wang W,Ning G

更新日期：2017-08-29 00:00:00

abstract：:For historic individuals, the outward appearance and other phenotypic characteristics remain often non-resolved. Unfortunately, images or detailed written sources are only scarcely available in many cases. Attempts to study historic individuals with genetic data so far focused on hypervariable regions of mitochondrial...

journal_title：Scientific reports

authors： Peltzer A,Mittnik A,Wang CC,Begg T,Posth C,Nieselt K,Krause J

更新日期：2018-02-01 00:00:00

abstract：:We present active manipulation of the structural vibrations of an elastic body to generate an acoustic illusion. The resultant illusion misrepresents the nature, size and number of objects in the exterior acoustic domain. We demonstrate our technique, herein termed active structural acoustic illusion, using an elastic...

journal_title：Scientific reports

authors： Eggler D,Kessissoglou N

更新日期：2020-06-17 00:00:00

abstract：:Demand is increasing for superhydrophobic materials in many applications, such as membrane distillation, separation and special coating technologies. In this study, we report a chemical vapor deposition (CVD) process to fabricate superhydrophobic carbon nanomaterials (CNM) on nickel (Ni)-doped powder activated carbon ...

journal_title：Scientific reports

authors： Aljumaily MM,Alsaadi MA,Das R,Hamid SBA,Hashim NA,AlOmar MK,Alayan HM,Novikov M,Alsalhy QF,Hashim MA

更新日期：2018-02-09 00:00:00

abstract：:Recent studies suggest that mRNAs may be differentially expressed between males and females. This study aimed to perform expression analysis of mRNA and its main regulatory molecule, microRNA (miRNA), to discuss the potential sex-specific expression patterns using abnormal expression profiles from The Cancer Genome At...

journal_title：Scientific reports

authors： Guo L,Zhang Q,Ma X,Wang J,Liang T

更新日期：2017-01-03 00:00:00

abstract：:Cytological and molecular studies have revealed that inversion chromosomal polymorphism is widespread across taxa and that inversions are among the most common structural changes fixed between species. Two major mechanisms have been proposed for the origin of inversions considering that breaks occur at either repetiti...

journal_title：Scientific reports

authors： Orengo DJ,Puerma E,Cereijo U,Aguadé M

更新日期：2019-11-18 00:00:00

abstract：:Solution Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy coupled with enzymatic hydrolysis (EH) with commercially available phosphatases was used to characterize phosphorus (P) compounds in extracts of the dominant aquatic macrophytes and algae in a eutrophic lake. Total extractable organic P (Po) conc...

journal_title：Scientific reports

authors： Feng W,Zhu Y,Wu F,He Z,Zhang C,Giesy JP

更新日期：2016-11-16 00:00:00

abstract：:Dysfunction or death of retinal pigment epithelial (RPE) cells is involved in some forms of Retinitis Pigmentosa and in age-related macular degeneration (AMD). Since there is no cure for most patients affected by these diseases, the transplantation of RPE cells derived from human pluripotent stem cells (hPSCs) represe...

journal_title：Scientific reports

authors： Regent F,Morizur L,Lesueur L,Habeler W,Plancheron A,Ben M'Barek K,Monville C

更新日期：2019-07-23 00:00:00

abstract：:Although plants are essentially sessile in nature, these organisms are very much in tune with their environment and are capable of a variety of movements. This may come as a surprise to many non-botanists, but not to Charles Darwin, who reported that plants do produce movements. Following Darwin's specific interest on...

journal_title：Scientific reports

authors： Guerra S,Peressotti A,Peressotti F,Bulgheroni M,Baccinelli W,D'Amico E,Gómez A,Massaccesi S,Ceccarini F,Castiello U

更新日期：2019-11-12 00:00:00

abstract：:Fc domain fusion can improve the therapeutic effects of relatively small biological molecules such as peptides, cytokines, and antibody fragments. Fc fusion proteins can also be used to enhance the cytotoxic effects of small bispecific antibodies (bsAbs). However, fragmentation of Fc fusion proteins, which mainly occu...

journal_title：Scientific reports

authors： Suzuki S,Annaka H,Konno S,Kumagai I,Asano R

更新日期：2018-11-22 00:00:00

abstract：:Recovery of nutrients and energy from municipal wastewater has attracted much attention in recent years; however, its efficiency is significantly limited by the low-strength properties of municipal wastewater. Herein, we report a pilot-scale forward osmosis (FO) system using a spiral-wound membrane module to concentra...

journal_title：Scientific reports

authors： Wang Z,Zheng J,Tang J,Wang X,Wu Z

更新日期：2016-02-22 00:00:00

abstract：:In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body's serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse primary cultures fired sp...

journal_title：Scientific reports

authors： Strege PR,Knutson K,Eggers SJ,Li JH,Wang F,Linden D,Szurszewski JH,Milescu L,Leiter AB,Farrugia G,Beyder A

更新日期：2017-11-15 00:00:00

abstract：:Ethoxyquin was recently identified as a neuroprotective compound against toxic neuropathies and efficacy was demonstrated against paclitaxel-induced neurotoxicity in vivo. In this study we examined the efficacy of ethoxyquin in preventing neurotoxicity of cisplatin in rodent models of chemotherapy-induced peripheral n...

journal_title：Scientific reports

authors： Zhu J,Carozzi VA,Reed N,Mi R,Marmiroli P,Cavaletti G,Hoke A

更新日期：2016-06-28 00:00:00

abstract：:Routine immunizations and supplementary immunization activities (SIAs) have significantly improved measles control over the past two decades in China. Progress towards eliminating measles currently faces multiple challenges as the infection age increases, and adult-targeted SIA strategies are being considered. This st...

journal_title：Scientific reports

authors： Chong KC,Zhang C,Jia KM,Zee BCY,Luo T,Wang L,Tam GCH,Sun R,Wang MH,Guan X

更新日期：2018-10-31 00:00:00