Inferring genetic origins and phenotypic traits of George Bähr, the architect of the Dresden Frauenkirche.

abstract：:Cancer vaccines are less effective at old than at young age because of immunosenescence. Besides, in preliminary observations we showed that the immunization with HER-2/neu DNA plasmid in transgenic young mice (standard immunization, SI) delays but not abrogate spontaneous mammary tumours progressively appearing durin...

journal_title：Scientific reports

authors： Provinciali M,Barucca A,Orlando F,Pierpaoli E

更新日期：2017-06-08 00:00:00

abstract：:Techniques that manipulate DNA, a biomolecule with electrical properties, are in demand in various medical fields. This study fabricated a nanochannel with a conductive/semi-conductive interface using focused ion beams (FIBs) and introduced a nanochip technology to freely align, attach, and detach lambda DNAs in the i...

journal_title：Scientific reports

authors： Kang K,Jang Y,Jung J,Oh J

更新日期：2019-02-26 00:00:00

abstract：:HPIVs are serologically and genetically grouped into four species that account for up to 10% of all hospitalizations due to acute respiratory infection in children under the age of five. Genetic and epidemiological data for the four HPIVs derived from two pediatric cohorts in Viet Nam are presented. Respiratory sample...

journal_title：Scientific reports

authors： Linster M,Do LAH,Minh NNQ,Chen Y,Zhe Z,Tuan TA,Tuan HM,Su YCF,van Doorn HR,Moorthy M,Smith GJD

更新日期：2018-05-01 00:00:00

abstract：:Near-critical plasmas irradiated at ultra-high laser intensities (I > 1018W/cm2) allow to improve the performances of laser-driven particle and radiation sources and to explore scenarios of great astrophysical interest. Near-critical plasmas with controlled properties can be obtained with nanostructured low-density ma...

journal_title：Scientific reports

authors： Fedeli L,Formenti A,Cialfi L,Pazzaglia A,Passoni M

更新日期：2018-03-01 00:00:00

abstract：:The therapeutic value of FK228 as a cancer treatment option is well known, and various types of cancer have been shown to respond to this drug. However, the complete mechanism of FK228 and the affect it has on histone lysine acetylation and the colon cancer cell proteome are largely unknown. In the present study, we u...

journal_title：Scientific reports

authors： Wang TY,Jia YL,Zhang X,Sun QL,Li YC,Zhang JH,Zhao CP,Wang XY,Wang L

更新日期：2015-12-17 00:00:00

abstract：:Although the perception of faces depends on low-level neuronal processes, it is also affected by high-level social processes. Faces from a social in-group, such as people of a similar age, receive more in-depth processing and are processed holistically. To explore whether own-age biases affect subconscious face percep...

journal_title：Scientific reports

authors： Nicholls MER,Churches O,Loetscher T

更新日期：2018-08-23 00:00:00

abstract：:In spite of extensive efforts over decades an experimentally-derived structure of full-length eukaryotic pentameric ligand-gated ion channels (pLGICs) is still lacking. These pharmaceutically highly-relevant channels contain structurally well-conserved and characterized extracellular and transmembrane domains. The int...

journal_title：Scientific reports

authors： Pandhare A,Grozdanov PN,Jansen M

更新日期：2016-04-05 00:00:00

abstract：:Massive gully land consolidation projects, launched in China's Loess Plateau, aim to restore 2667 [Formula: see text] agricultural lands in total by consolidating 2026 highly eroded gullies. This effort represents a social engineering project where the economic development and livelihood of the farming families are cl...

journal_title：Scientific reports

authors： Yan Q,Kumar P,Wang Y,Zhao Y,Lin H,Ran Q,An Z,Zhou W

更新日期：2020-10-09 00:00:00

abstract：:The FGF receptor signaling pathway is recurrently involved in the leukemogenic processes. Oncogenic fusions of FGFR1 with various fusion partners were described in myeloid proliferative neoplasms, and overexpression and mutations of FGFR3 are common in multiple myeloma. In addition, fibroblast growth factors are abund...

journal_title：Scientific reports

authors： Jerchel IS,Hoogkamer AQ,Ariës IM,Boer JM,Besselink NJM,Koudijs MJ,Pieters R,den Boer ML

更新日期：2019-02-12 00:00:00

abstract：:The interaction of a mechanical oscillator with the operation actions and environment fields will give rise to the splitting of normal modes. In this study, we investigate the normal mode splitting behaviour of a moving-particles-pumped single-span clamped-hinged elastic homogeneous beam based on the proposed multi-oc...

journal_title：Scientific reports

authors： Sun Z

更新日期：2018-06-28 00:00:00

abstract：:Solid solutions of Zr(Mo,W)2O7(OH,Cl)2∙2H2O with a preset ratio of components were prepared by a hydrothermal method. The chemical composition of the solutions was determined by energy dispersive X-ray spectroscopy (EDX). For all the samples of ZrMoxW2-xO7(OH,Cl)2∙2H2O (x = 0.0, 0.2, 0.4, 0.6, 0.8, 1.0, 1.2, 1.4, 1.6,...

journal_title：Scientific reports

authors： Petrushina MY,Dedova ES,Filatov EY,Plyusnin PE,Korenev SV,Kulkov SN,Derevyannikova EA,Sharafutdinov MR,Gubanov AI

更新日期：2018-03-28 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Gibson KM,Jair K,Castel AD,Bendall ML,Wilbourn B,Jordan JA,Crandall KA,Pérez-Losada M,DC Cohort Executive Committee.

更新日期：2020-04-22 00:00:00

abstract：:Muscular dystrophy-dystroglycanopathies comprise a heterogeneous and complex group of disorders caused by loss-of-function mutations in a multitude of genes that disrupt the glycobiology of α-dystroglycan, thereby affecting its ability to function as a receptor for extracellular matrix proteins. Of the various genes i...

journal_title：Scientific reports

authors： Vannoy CH,Leroy V,Broniowska K,Lu QL

更新日期：2019-07-11 00:00:00

abstract：:In arid and semiarid regions, low precipitation rates lead to soil salinity problems, which may limit plant establishment, growth, and survival. Herein, we investigated the NaCl stress effect on chlorophyll fluorescence, photosynthetic-pigments, movement and chloroplasts ultrastructure in chlorenchyma cells of Opuntia...

journal_title：Scientific reports

authors： Arias-Moreno DM,Jiménez-Bremont JF,Maruri-López I,Delgado-Sánchez P

更新日期：2017-08-17 00:00:00

abstract：:In the attempt of implementing iron garnets with perpendicular magnetic anisotropy (PMA) in spintronics, the attention turned towards strain-grown iron garnets. One candidate is Tm3Fe5O12 (TmIG) which possesses an out-of-plane magnetic easy axis when grown under tensile strain. In this study, the effect of film thickn...

journal_title：Scientific reports

authors： Ciubotariu O,Semisalova A,Lenz K,Albrecht M

更新日期：2019-11-25 00:00:00

abstract：:Landscape's spatial structure has vast implications for the dynamics and distribution of species populations and ecological communities. However, the characterization of the structure of spatial networks has not received nearly as much attention as networks of species interactions counterparts. Recent experiments show...

journal_title：Scientific reports

authors： Gilarranz LJ

更新日期：2020-05-26 00:00:00

abstract：:Osthole, an active coumarin isolated from Cnidium monnieri (L.) Cusson, has long been used in China as an antipruritic herbal medicine; however, the antipruitic mechanism of osthole is unknown. We studied the molecular mechanism of osthole in histamine-dependent itch by behavioral test, Ca(2+) imaging, and electrophys...

journal_title：Scientific reports

authors： Yang NN,Shi H,Yu G,Wang CM,Zhu C,Yang Y,Yuan XL,Tang M,Wang ZL,Gegen T,He Q,Tang K,Lan L,Wu GY,Tang ZX

更新日期：2016-05-10 00:00:00

abstract：:The type II bacterial CRISPR/Cas9 system is rapidly becoming popular for genome-engineering due to its simplicity, flexibility, and high efficiency. Recently, targeted knock-in of a long DNA fragment via homology-independent DNA repair has been achieved in zebrafish using CRISPR/Cas9 system. This raised the possibilit...

journal_title：Scientific reports

authors： Kimura Y,Hisano Y,Kawahara A,Higashijima S

更新日期：2014-10-08 00:00:00

abstract：:Chemical purity of RNA samples is important for high-precision studies of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sample preparation can reduce this purity. Here, we report the quantitation of UV-induced damage by using reverse transcription and single-nuc...

journal_title：Scientific reports

authors： Kladwang W,Hum J,Das R

更新日期：2012-01-01 00:00:00

abstract：:Diabetes is a chronic metabolic disease that causes blood glucose (BG) concentration to make dangerous excursions outside its physiological range. Measuring the fraction of time spent by BG outside this range, and, specifically, the time-below-range (TBR), is a clinically common way to quantify the effectiveness of th...

journal_title：Scientific reports

authors： Camerlingo N,Vettoretti M,Facchinetti A,Sparacino G,Mader JK,Choudhary P,Del Favero S

更新日期：2020-10-23 00:00:00

abstract：:Previous reports on epigenetic mechanisms involved in alcohol abuse have focus on hepatic and neuronal regions, leaving the immune system and specifically monocyte-derived dendritic cells (MDDCs) understudied. Our lab has previously shown histone deacetylases are modulated in cells derived from alcohol users and after...

journal_title：Scientific reports

authors： Parira T,Figueroa G,Laverde A,Casteleiro G,Gomez Hernandez ME,Fernandez-Lima F,Agudelo M

更新日期：2017-09-11 00:00:00

abstract：:The studies on the increasing incidence of thyroid abnormalities are scarce. The aim of this current study was to ascertain the effects of geographical region on thyroid abnormalities under the context of universal salt iodization (USI). We randomly selected 1255 participants residing in inland and 1248 in coast, with...

journal_title：Scientific reports

authors： Wang X,Mo Z,Mao G,Zhu W,Xing M,Li X,Wang Y,Wang Z,Lou X

更新日期：2021-01-13 00:00:00

abstract：:Bariatric surgery is the most effective treatment for weight loss. Vertical sleeve gastrectomy (VSG) involves the resection of ~ 80% of the stomach and was conceived to purely restrict oral intake. However, evidence suggests more complex mechanisms, particularly postoperative changes in gut microbiota, in facilitating...

journal_title：Scientific reports

authors： Nalluri H,Kizy S,Ewing K,Luthra G,Leslie DB,Bernlohr DA,Sadowsky MJ,Ikramuddin S,Khoruts A,Staley C,Jahansouz C

更新日期：2020-11-23 00:00:00

abstract：:An available pathway to prepare the ionized covalent organic nanosheets (iCONs) has been proposed by a metal-assisted aqueous-phase exfoliation route from covalent organic frameworks. The soluble and belt-shaped iCONs could immobilize a large quantity of proteins (2.73 mg/mg, BSA/iCONs) and hence serve as transporters...

journal_title：Scientific reports

authors： Kong W,Wan J,Namuangruk S,Guo J,Wang C

更新日期：2018-04-03 00:00:00

abstract：:Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...

journal_title：Scientific reports

authors： Miyoshi Y,Kondo Y,Hirano Y,Ishihara T,Sueyoshi K,Okamoto K,Tanaka H

更新日期：2020-11-05 00:00:00

abstract：:An isolated black yeast-like strain was obtained from radiation-polluted soil collected from Xinjiang province in northwest China. On the basis of ITS and LSU rDNA sequence analysis, in combination with the colony morphology and phenotypic properties, the isolated strain was revealed to represent a novel variety of Au...

journal_title：Scientific reports

authors： Liu T,Zhu L,Zhang Z,Huang H,Zhang Z,Jiang L

更新日期：2017-12-14 00:00:00

abstract：:Dysregulation of iron metabolism, and resultant cytotoxicity, has been implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative processes. Iron accumulation promotes cytotoxicity through various mechanisms including oxidative stress and glutamate toxicity, and occurs in both MS patients an...

journal_title：Scientific reports

authors： Khan RS,Baumann B,Dine K,Song Y,Dunaief JL,Kim SF,Shindler KS

更新日期：2019-08-12 00:00:00

abstract：:This work highlights the possibility of using microstructured fibres with predefined doped regions to produce functional microstructures at a fibre facet with differential chemical etching. A specially designed silica microstructured fibre (MSF) that possesses specific boron-doped silica regions was fabricated for the...

journal_title：Scientific reports

authors： Fu Y,Morency S,Bachus K,Simon D,Hutama T,Gibson GTT,Messaddeq Y,Oleschuk RD

更新日期：2016-02-19 00:00:00

abstract：:Evaluation of precipitation and nitrogen (N) deposition in desert ecosystems helps to elucidate the reaction of desert ecosystems to future environmental changes. An in-situ field experiment was established to examine the influence of a long-term enhanced precipitation and N deposition on the photosynthetic traits and...

journal_title：Scientific reports

authors： Zhao WQ,Lv XH,Li YG,Wang ZK,Zhang W,Zhuang L

更新日期：2019-03-08 00:00:00

abstract：:Recent studies suggest that spatial training can maintain associative memory capacity in Tg2576 mice, but it is not known whether the beneficial effects can be inherited from the trained fathers to their offspring. Here, we exposed male wild-type and male 3XTg Alzheimer disease (AD) mice (3-m old) respectively to spat...

journal_title：Scientific reports

authors： Zhang S,Li X,Wang Z,Liu Y,Gao Y,Tan L,Liu E,Zhou Q,Xu C,Wang X,Liu G,Chen H,Wang JZ

更新日期：2017-05-08 00:00:00