当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > The molecular genealogy of sequential overlapping inversions implies both homologous chromosomes of a heterokaryotype in an inversion origin.

The molecular genealogy of sequential overlapping inversions implies both homologous chromosomes of a heterokaryotype in an inversion origin.

Abstract：

:Cytological and molecular studies have revealed that inversion chromosomal polymorphism is widespread across taxa and that inversions are among the most common structural changes fixed between species. Two major mechanisms have been proposed for the origin of inversions considering that breaks occur at either repetitive or non-homologous sequences. While inversions originating through the first mechanism might have a multiple origin, those originating through the latter mechanism would have a unique origin. Variation at regions flanking inversion breakpoints can be informative on the origin and history of inversions given the reduced recombination in heterokaryotypes. Here, we have analyzed nucleotide variation at a fragment flanking the most centromere-proximal shared breakpoint of several sequential overlapping inversions of the E chromosome of Drosophila subobscura -inversions E1, E2, E9 and E3. The molecular genealogy inferred from variation at this shared fragment does not exhibit the branching pattern expected according to the sequential origin of inversions. The detected discordance between the molecular and cytological genealogies has led us to consider a novel possibility for the origin of an inversion, and more specifically that one of these inversions originated on a heterokaryotype for chromosomal arrangements. Based on this premise, we propose three new models for inversions origin.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Orengo DJ,Puerma E,Cereijo U,Aguadé M

doi

10.1038/s41598-019-53582-8

subject

Has Abstract

pub_date

2019-11-18 00:00:00

pages

17009

issue

1

issn

2045-2322

pii

10.1038/s41598-019-53582-8

journal_volume

9

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans.

    abstract：:How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of seven genes that we...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep00487

    authors： Honda Y,Higashibata A,Matsunaga Y,Yonezawa Y,Kawano T,Higashitani A,Kuriyama K,Shimazu T,Tanaka M,Szewczyk NJ,Ishioka N,Honda S

    更新日期：2012-01-01 00:00:00

  • Extensive vegetation browning and drying in forests of India's Tiger Reserves.

    abstract：:Forest conservation includes stemming deforestation as well as preserving its vegetation condition. Traditional Protected Area (PA) effectiveness evaluations have assessed changes in forest extent but have mostly ignored vegetation condition. Tiger Reserves (TRs) are India's PAs with highest protection and management ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-51118-8

    authors： Koulgi PS,Clinton N,Karanth KK

    更新日期：2019-10-18 00:00:00

  • A ruthenium(II) complex as turn-on Cu(II) luminescent sensor based on oxidative cyclization mechanism and its application in vivo.

    abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep08172

    authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

    更新日期：2015-02-02 00:00:00

  • Tracking capsule activation and crack healing in a microcapsule-based self-healing polymer.

    abstract：:Structural polymeric materials incorporating a microencapsulated liquid healing agent demonstrate the ability to autonomously heal cracks. Understanding how an advancing crack interacts with the microcapsules is critical to optimizing performance through tailoring the size, distribution and density of these capsules. ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-54242-7

    authors： McDonald SA,Coban SB,Sottos NR,Withers PJ

    更新日期：2019-11-28 00:00:00

  • Dynamic plant height QTL revealed in maize through remote sensing phenotyping using a high-throughput unmanned aerial vehicle (UAV).

    abstract：:Plant height (PH) is a key factor in maize (Zea mays L.) yield, biomass, and plant architecture. We investigated the PH of diverse maize inbred lines (117 temperate lines, 135 tropical lines) at four growth stages using unmanned aerial vehicle high-throughput phenotypic platforms (UAV-HTPPs). We extracted PH data usin...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-39448-z

    authors： Wang X,Zhang R,Song W,Han L,Liu X,Sun X,Luo M,Chen K,Zhang Y,Yang H,Yang G,Zhao Y,Zhao J

    更新日期：2019-03-05 00:00:00

  • Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis.

    abstract：:Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, current TNF-α blockers...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25652-w

    authors： Cui X,Chang L,Li Y,Lv Q,Wang F,Lin Y,Li W,Meade JD,Walden JC,Liang P

    更新日期：2018-05-09 00:00:00

  • Toxic metabolites, MAPK and Nrf2/Keap1 signaling pathways involved in oxidative toxicity in mice liver after chronic exposure to Mequindox.

    abstract：:Mequindox (MEQ) is a synthetic antimicrobial agent of quinoxaline-1,4-dioxide group (QdNOs). The liver is regarded as the toxicity target of QdNOs, and the role of N → O group-associated various toxicities mediated by QdNOs is well recognized. However, the mechanism underlying the in vivo effects of MEQ on the liver, ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep41854

    authors： Liu Q,Lei Z,Huang A,Wu Q,Xie S,Awais I,Dai M,Wang X,Yuan Z

    更新日期：2017-02-03 00:00:00

  • EDX-analysis of fluoride precipitation on human enamel.

    abstract：:One mechanism of action for the anticaries effect of topical fluoridation is through precipitation of CaF2. In this in vitro study energy-dispersive x-ray spectroscopy (EDX) is used as a semiquantitative method to detect enamel fluoride-precipitation under the influence of acidic and neutral pH-value and absence or pr...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-49742-5

    authors： Scholz KJ,Federlin M,Hiller KA,Ebensberger H,Ferstl G,Buchalla W

    更新日期：2019-09-17 00:00:00

  • Mutation of two key aspartate residues alters stoichiometry of the NhaB Na+/H+ exchanger from Klebsiella pneumoniae.

    abstract：:Bacterial NhaB Na+/H+ exchangers belonging to the Ion Transporter superfamily are poorly characterized in contrast to Na+/H+ exchangers of the Cation Proton Antiporter superfamily which have NhaA from Escherichia coli as a prominent member. For a more detailed understanding of the intricacies of the exchanger's transp...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-51887-2

    authors： Patiño-Ruiz M,Fendler K,Călinescu O

    更新日期：2019-10-28 00:00:00

  • Identification of candidate miRNAs in early-onset and late-onset prostate cancer by network analysis.

    abstract：:The incidence of patients under 55 years old diagnosed with Prostate Cancer (EO-PCa) has increased during recent years. The molecular biology of PCa cancer in this group of patients remains unclear. Here, we applied weighted gene coexpression network analysis of the expression of miRNAs from 24 EO-PCa patients (38-45 ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-69290-7

    authors： Parra-Medina R,López-Kleine L,Ramírez-Clavijo S,Payán-Gómez C

    更新日期：2020-07-23 00:00:00

  • Publisher Correction: A Computational Method to Quantify the Effects of Slipped Strand Mispairing on Bacterial Tetranucleotide Repeats.

    abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-020-58622-2

    authors： Harhay GP,Harhay DM,Bono JL,Capik SF,DeDonder KD,Apley MD,Lubbers BV,White BJ,Larson RL,Smith TPL

    更新日期：2020-01-28 00:00:00

  • Plasmonic silver quantum dots coupled with hierarchical TiO2 nanotube arrays photoelectrodes for efficient visible-light photoelectrocatalytic hydrogen evolution.

    abstract：:A plasmonic Ag/TiO2 photocatalytic composite was designed by selecting Ag quantum dots (Ag QDs) to act as a surface plasmon resonance (SPR) photosensitizer for driving the visible-light driven photoelectrocatalytic hydrogen evolution. Vertically oriented hierarchical TiO2 nanotube arrays (H-TiO2-NTAs) with macroporous...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep10461

    authors： Lian Z,Wang W,Xiao S,Li X,Cui Y,Zhang D,Li G,Li H

    更新日期：2015-06-12 00:00:00

  • In vitro biological screening of a critically endangered medicinal plant, Atropa acuminata Royle Ex Lindl of north western Himalaya.

    abstract：:Atropa acuminata Royle Ex Lindl (Atropa acuminata) under tremendous threat of extinction in its natural habitat. However, the antimicrobial, antileishmanial and anticancer effects of the plant's extracts have not been reported yet. In the current study, an attempt has been made to evaluate the pharmacological potentia...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-29231-x

    authors： Rahman K,Khan SU,Fahad S,Shinwari ZK,Khan D,Kamal S,Ullah I,Anjum SI,Man S,Khan AJ,Khan WU,Khan MHU,Jan M,Adnan M,Noor M

    更新日期：2018-07-23 00:00:00

  • Global Trends and Regional Variations in Studies of HIV/AIDS.

    abstract：:We conduct textual analysis of a sample of more than 200,000 papers written on HIV/AIDS during the past three decades. Using the Latent Dirichlet Allocation method, we disentangle studies that address behavioral and social aspects from other studies and measure the trends of different topics as related to HIV/AIDS. We...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-04527-6

    authors： Baghaei Lakeh A,Ghaffarzadegan N

    更新日期：2017-06-23 00:00:00

  • High-affinity Cu(I) chelator PSP-2 as potential anti-angiogenic agent.

    abstract：:Copper is an essential trace metal that has been implicated in angiogenesis, the formation of new blood vessels. As tumor growth relies on establishing a functional capillary network for blood supply, copper chelation therapy may hold promise as an anti-cancer strategy by suppressing angiogenesis. To test the anti-ang...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-50494-5

    authors： Heuberger DM,Harankhedkar S,Morgan T,Wolint P,Calcagni M,Lai B,Fahrni CJ,Buschmann J

    更新日期：2019-10-01 00:00:00

  • Computational Classification Approach to Profile Neuron Subtypes from Brain Activity Mapping Data.

    abstract：:The analysis of cell type-specific activity patterns during behaviors is important for better understanding of how neural circuits generate cognition, but has not been well explored from in vivo neurophysiological datasets. Here, we describe a computational approach to uncover distinct cell subpopulations from in vivo...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep12474

    authors： Li M,Zhao F,Lee J,Wang D,Kuang H,Tsien JZ

    更新日期：2015-07-27 00:00:00

  • Fabrication of copper(II)-coated magnetic core-shell nanoparticles Fe3O4@SiO2-2-aminobenzohydrazide and investigation of its catalytic application in the synthesis of 1,2,3-triazole compounds.

    abstract：:In the present work, an attempt has been made to synthesize the 1,2,3-triazole derivatives resulting from the click reaction, in a mild and green environment using the new copper(II)-coated magnetic core-shell nanoparticles Fe3O4@SiO2 modified by isatoic anhydride. The structure of the catalyst has been determined by ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-021-81632-7

    authors： Rajabi-Moghaddam H,Naimi-Jamal MR,Tajbakhsh M

    更新日期：2021-01-22 00:00:00

  • Precise Doppler shift compensation in the hipposiderid bat, Hipposideros armiger.

    abstract：:Bats of the Rhinolophidae and Hipposideridae families, and Pteronotus parnellii, compensate for Doppler shifts generated by their own flight movement. They adjust their call frequency such that the frequency of echoes coming from ahead fall in a specialized frequency range of the hearing system, the auditory fovea, to...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-22880-y

    authors： Schoeppler D,Schnitzler HU,Denzinger A

    更新日期：2018-03-15 00:00:00

  • Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model.

    abstract：:The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypi...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25461-1

    authors： Morgan MM,Livingston MK,Warrick JW,Stanek EM,Alarid ET,Beebe DJ,Johnson BP

    更新日期：2018-05-08 00:00:00

  • Cell sorting in a Petri dish controlled by computer vision.

    abstract：:Fluorescence-activated cell sorting (FACS) applying flow cytometry to separate cells on a molecular basis is a widespread method. We demonstrate that both fluorescent and unlabeled live cells in a Petri dish observed with a microscope can be automatically recognized by computer vision and picked up by a computer-contr...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep01088

    authors： Környei Z,Beke S,Mihálffy T,Jelitai M,Kovács KJ,Szabó Z,Szabó B

    更新日期：2013-01-01 00:00:00

  • Salinity altered root distribution and increased diversity of bacterial communities in the rhizosphere soil of Jerusalem artichoke.

    abstract：:The interaction between roots and bacterial communities in halophytic species is poorly understood. Here, we used Jerusalem artichoke cultivar Nanyu 1 (NY-1) to characterise root distribution patterns and determine diversity and abundance of bacteria in the rhizosphere soil under variable salinity. Root growth was not...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep20687

    authors： Yang H,Hu J,Long X,Liu Z,Rengel Z

    更新日期：2016-02-08 00:00:00

  • A Novel Geometry-Based Approach to Infer Protein Interface Similarity.

    abstract：:The protein interface is key to understand protein function, providing a vital insight on how proteins interact with each other and with other molecules. Over the years, many computational methods to compare protein structures were developed, yet evaluating interface similarity remains a very difficult task. Here, we ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-26497-z

    authors： Budowski-Tal I,Kolodny R,Mandel-Gutfreund Y

    更新日期：2018-05-29 00:00:00

  • Transcriptome profiling of spike provides expression features of genes related to terpene biosynthesis in lavender.

    abstract：:Lavender (Lavandula angustifolia) is an important economic plant because of the value of its essential oil (EO). The Yili Valley in Xinjiang has become the largest lavender planting base in China. However, there is a lack of research on the gene expression regulation of EO biosynthesis and metabolism in local varietie...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-63950-4

    authors： Guo D,Kang K,Wang P,Li M,Huang X

    更新日期：2020-04-24 00:00:00

  • Trends in cardiovascular risk factors in diabetic patients in comparison to general population in Iran: findings from National Surveys 2007-2016.

    abstract：:To determine levels of change in risk factors for cardiovascular disease among people with and without a previous diagnosis of diabetes from 2007 to 2016 in Iran. Data were obtained from five rounds of the World Health Organization STEPwise approach to Surveillance (STEPS) cross-sectional surveys. Participants were 76...

    journal_title：Scientific reports

    pub_type： 历史文章,杂志文章

    doi：10.1038/s41598-020-68640-9

    authors： Malekzadeh H,Lotfaliany M,Ostovar A,Hadaegh F,Azizi F,Yoosefi M,Farzadfar F,Khalili D

    更新日期：2020-07-16 00:00:00

  • Molecular architecture of the Ub-PCNA/Pol η complex bound to DNA.

    abstract：:Translesion synthesis (TLS) is the mechanism by which DNA polymerases replicate through unrepaired DNA lesions. TLS is activated by monoubiquitination of the homotrimeric proliferating cell nuclear antigen (PCNA) at lysine-164, followed by the switch from replicative to specialized polymerases at DNA damage sites. Pol...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep15759

    authors： Lau WC,Li Y,Zhang Q,Huen MS

    更新日期：2015-10-27 00:00:00

  • Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons.

    abstract：:IgLONs are members of the immunoglobulin superfamily of cell adhesion proteins implicated in the process of neuronal outgrowth, cell adhesion and subdomain target recognition. IgLONs form homophilic and heterophilic complexes on the cell surface that repress or promote growth depending on the neuronal population, the ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-08315-0

    authors： Sanz RL,Ferraro GB,Girouard MP,Fournier AE

    更新日期：2017-08-11 00:00:00

  • Emergence of soft communities from geometric preferential attachment.

    abstract：:All real networks are different, but many have some structural properties in common. There seems to be no consensus on what the most common properties are, but scale-free degree distributions, strong clustering, and community structure are frequently mentioned without question. Surprisingly, there exists no simple gen...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep09421

    authors： Zuev K,Boguñá M,Bianconi G,Krioukov D

    更新日期：2015-04-29 00:00:00

  • Association between Copy Number Variation and Response to Social Skills Training in Autism Spectrum Disorder.

    abstract：:Challenges in social communication and interaction are core features of autism spectrum disorder (ASD) for which social skills group training (SSGT) is a commonly used intervention. SSGT has shown modest and heterogeneous effects. One of the major genetic risk factors in ASD is rare copy number variation (CNV). Howeve...

    journal_title：Scientific reports

    pub_type： 杂志文章,多中心研究

    doi：10.1038/s41598-019-46396-1

    authors： Tammimies K,Li D,Rabkina I,Stamouli S,Becker M,Nicolaou V,Berggren S,Coco C,Falkmer T,Jonsson U,Choque-Olsson N,Bölte S

    更新日期：2019-07-08 00:00:00

  • Random lasing in human tissues embedded with organic dyes for cancer diagnosis.

    abstract：:Various nanostructures found in biological organisms are often complex and they exhibit unique optical functions. This study surprisingly found that typical random lasing occurs in cancerous human tissues embedded with the nanotextured organic dye 4-(dicyanomethylene)-2-tert-butyl-6-(1,1,7,7- tetramethyljulolidyl-9-en...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-08625-3

    authors： Wang Y,Duan Z,Qiu Z,Zhang P,Wu J,Zhang D,Xiang T

    更新日期：2017-08-21 00:00:00

  • SLINGER: large-scale learning for predicting gene expression.

    abstract：:Recent studies have established that single nucleotide polymorphisms are sufficient to build accurate predictive models of gene expression. Gamazon, et al., found that gene expression values predicted from cis neighborhood SNPs show statistical association with disease status. In this work, we remove the cis neighborh...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep39360

    authors： Vervier K,Michaelson JJ

    更新日期：2016-12-20 00:00:00