Identification of candidate miRNAs in early-onset and late-onset prostate cancer by network analysis.

abstract：:Platelet transfusions can cause adverse reactions in their recipients, including transfusion-related acute lung injury (TRALI). The pathophysiology of TRALI depends on a number of signaling pathways and the inflammatory role played by blood platelets remains controversial. Platelets are important in inflammation, part...

journal_title：Scientific reports

authors： Tariket S,Hamzeh-Cognasse H,Laradi S,Arthaud CA,Eyraud MA,Bourlet T,Berthelot P,Garraud O,Cognasse F

更新日期：2019-08-29 00:00:00

abstract：:Salts containing radical cations of 1,2,4,5-tetrakis(isopropylthio)benzene (TPB) and 1,2,4,5-tetrakis(ethylthio) benzene (TEB) have been successfully synthesized with . These newly synthesized salts have been characterized by UV-Vis absorption, EPR spectroscopy, conductivity measurement, single crystal X-ray diffracti...

journal_title：Scientific reports

authors： Chen X,Gao F,Yang W

更新日期：2016-07-11 00:00:00

abstract：:The effect of resistin (RETN) on the response to anti-HCV therapy remains unclear. A prospective cohort study was performed using 655 consecutive HCV patients, of whom 513 had completed a course of interferon-based therapy. Multivariate and GEE analyses revealed four RETN single-nucleotide polymorphisms (SNPs), rs3486...

journal_title：Scientific reports

authors： Chang ML,Liang KH,Ku CL,Lo CC,Cheng YT,Hsu CM,Yeh CT,Chiu CT

更新日期：2016-08-01 00:00:00

abstract：:Sensitive High-Resolution Ion Microprobe (SHRIMP) U-Pb analyses of zircons from Paleoarchean (~3.4 Ga) tonalite-gneiss called the Older Metamorphic Tonalitic Gneiss (OMTG) from the Champua area of the Singhbhum Craton, India, reveal 4.24-4.03 Ga xenocrystic zircons, suggesting that the OMTG records the hitherto unknow...

journal_title：Scientific reports

authors： Chaudhuri T,Wan Y,Mazumder R,Ma M,Liu D

更新日期：2018-05-04 00:00:00

abstract：:The successful determination of reliable protein interaction networks (PINs) in several species in the post-genomic era has hitherto facilitated the quest to understanding systems and structural properties of such networks. It is envisaged that a clearer understanding of their intrinsic topological properties would el...

journal_title：Scientific reports

authors： Fadhal E,Gamieldien J,Mwambene EC

更新日期：2015-02-27 00:00:00

abstract：:The effect of substitution of Nb by Mo in Nb40Ti30Ni30 was investigated with respect to microstructural features and hydrogen dissolution, diffusion and permeation. As-cast Nb40-xMoxTi30Ni30 (x = 0, 5, 10) alloys consist of primary bcc-Nb phase and binary eutectic (bcc-Nb + B2-TiNi). The substitution of Nb by Mo reduc...

journal_title：Scientific reports

authors： Li X,Liang X,Liu D,Chen R,Huang F,Wang R,Rettenmayr M,Su Y,Guo J,Fu H

更新日期：2017-03-16 00:00:00

abstract：:Cartilage repair in osteoarthritic patients remains a challenge. Identifying resident or donor stem/progenitor cell populations is crucial for augmenting the low intrinsic repair potential of hyaline cartilage. Furthermore, mediating the interaction between these cells and the local immunogenic environment is thought ...

journal_title：Scientific reports

authors： Bauza G,Pasto A,Mcculloch P,Lintner D,Brozovich A,Niclot FB,Khan I,Francis LW,Tasciotti E,Taraballi F

更新日期：2020-10-06 00:00:00

abstract：:Breast cancer brain metastasis (BCBM) remains a major clinical problem. Approximately 10-16% of patients with breast cancer develop brain metastases (BCBM). However, no systemic therapy has gained regulatory approval for the specific treatment of BCBM and this remains an area of persistent, unmet medical need. Rapid, ...

journal_title：Scientific reports

authors： Liu Z,Wang Y,Kabraji S,Xie S,Pan P,Liu Z,Ni J,Zhao JJ

更新日期：2019-01-24 00:00:00

abstract：:This retrospective study was undertaken to provide more modern data of real-life management of non-metastatic rectal cancer, to compare therapeutic strategies, and to identify prognostic factors of overall survival (OS) in a large cohort of patients. Data on efficacy and on acute/late toxicity were retrospectively col...

journal_title：Scientific reports

authors： Langrand-Escure J,Diao P,Garcia MA,Wang G,Guy JB,Espenel S,Guillaume E,Rehailia-Blanchard A,Pigné G,de Laroche G,Kaczmarek D,Muron T,Porcheron J,Phelip JM,Vallard A,Magné N

更新日期：2018-07-16 00:00:00

abstract：:Biclustering algorithms, which aim to provide an effective and efficient way to analyze gene expression data by finding a group of genes with trend-preserving expression patterns under certain conditions, have been widely developed since Morgan et al. pioneered a work about partitioning a data matrix into submatrices ...

journal_title：Scientific reports

authors： Wang Z,Li G,Robinson RW,Huang X

更新日期：2016-03-22 00:00:00

abstract：:The formation of snow-dirt sludge (SDS) via the mixing of snow and surface-deposited sediment by vehicles and pedestrians is one of the least studied sedimentation processes in urban areas. The aim of this study was to analyse the material, mineral, particle size, and chemical compositions of the SDS solid phase. The ...

journal_title：Scientific reports

authors： Seleznev A,Yarmoshenko I,Malinovsky G,Ilgasheva E,Baglaeva E,Ryanskaya A,Kiseleva D,Gulyaeva T

更新日期：2019-11-21 00:00:00

abstract：:Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied, the spatial distribution and the seq...

journal_title：Scientific reports

authors： Zhang S,Xu M,Qiu Z,Wang K,Du Y,Gu L,Cui X

更新日期：2016-03-18 00:00:00

abstract：:Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shikimate kinase I and...

journal_title：Scientific reports

authors： Gu P,Su T,Wang Q,Liang Q,Qi Q

更新日期：2016-07-13 00:00:00

abstract：:Electric double-layer capacitors (EDLCs) or supercapacitors (SCs) are fast energy storage devices with high pulse efficiency and superior cyclability, which makes them useful in various applications including electronics, vehicles and grids. Aqueous SCs are considered to be more environmentally friendly than those bas...

journal_title：Scientific reports

authors： Blomquist N,Wells T,Andres B,Bäckström J,Forsberg S,Olin H

更新日期：2017-01-05 00:00:00

abstract：:ZnO, aside from TiO2, has been considered as a promising material for purification and disinfection of water and air, and remediation of hazardous waste, owing to its high activity, environment-friendly feature and lower cost. However, their poor visible light utilization greatly limited their practical applications. ...

journal_title：Scientific reports

authors： Zhang X,Qin J,Xue Y,Yu P,Zhang B,Wang L,Liu R

更新日期：2014-04-04 00:00:00

abstract：:Propagation of coherent light through a disordered network is accompanied by randomization and possible conversion into thermal light. Here, we show that network topology plays a decisive role in determining the statistics of the emerging field if the underlying lattice is endowed with chiral symmetry. In such lattice...

journal_title：Scientific reports

authors： Kondakci HE,Abouraddy AF,Saleh BEA

更新日期：2017-08-21 00:00:00

abstract：:Accumulating of evidence suggests that activation of nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs) exacerbates early brain injury (EBI) following subarachnoid hemorrhage (SAH) by provoking pro-inflammatory and pro-apoptotic signaling. Myeloid differentiation primary response protein 88 (...

journal_title：Scientific reports

authors： Yan H,Zhang D,Wei Y,Ni H,Liang W,Zhang H,Hao S,Jin W,Li K,Hang CH

更新日期：2017-11-17 00:00:00

abstract：:The taxonomic composition of egg-associated microbial communities can play a crucial role in the development of fish embryos. In response, hosts increasingly influence the composition of their associated microbial communities during embryogenesis, as concluded from recent field studies and laboratory experiments. Howe...

journal_title：Scientific reports

authors： Wilkins LG,Rogivue A,Schütz F,Fumagalli L,Wedekind C

更新日期：2015-11-27 00:00:00

abstract：:We have developed a computational method that counts the frequencies of unique k-mers in FASTQ-formatted genome data and uses this information to infer the genotypes of known variants. FastGT can detect the variants in a 30x genome in less than 1 hour using ordinary low-cost server hardware. The overall concordance wi...

journal_title：Scientific reports

authors： Pajuste FD,Kaplinski L,Möls M,Puurand T,Lepamets M,Remm M

更新日期：2017-05-31 00:00:00

abstract：:The cannabinoid type 1 (CB1) receptor and the capsaicin receptor (TRPV1) exhibit co-expression and complex, but largely unknown, functional interactions in a sub-population of primary sensory neurons (PSN). We report that PSN co-expressing CB1 receptor and TRPV1 form two distinct sub-populations based on their pharmac...

journal_title：Scientific reports

authors： Chen J,Varga A,Selvarajah S,Jenes A,Dienes B,Sousa-Valente J,Kulik A,Veress G,Brain SD,Baker D,Urban L,Mackie K,Nagy I

更新日期：2016-09-22 00:00:00

abstract：:Aluminum (Al) toxicity is a serious problem for rice crop productivity in acidic soils worldwide. The present work was conducted to look out for the alteration in ROS homeostasis; metabolic fingerprint; and morphology in two contrasting Indica rice cultivars of North East India (NE India) to Al toxicity. Al stress led...

journal_title：Scientific reports

authors： Awasthi JP,Saha B,Panigrahi J,Yanase E,Koyama H,Panda SK

更新日期：2019-06-18 00:00:00

abstract：:Quantum walk is a key operation in quantum computing, simulation, communication and information. Here, we report for the first time the demonstration of quantum walks and localized quantum walks in a new type of optical fibers having a ring of cores constructed with both periodic and quasiperiodic Fibonacci sequences,...

journal_title：Scientific reports

authors： Nguyen DT,Nguyen TA,Khrapko R,Nolan DA,Borrelli NF

更新日期：2020-04-28 00:00:00

abstract：:Pertuzumab is an antihuman HER2 antibody developed for HER2 positive breast cancer. Glycosylation profiles are always the important issue for antibody based therapy. Previous findings have suggested the impact of glycosylation profiles on the function of antibodies, like pharmacodynamics, antibody-dependent cellular c...

journal_title：Scientific reports

authors： Luo C,Chen S,Xu N,Wang C,Sai WB,Zhao W,Li YC,Hu XJ,Tian H,Gao XD,Yao WB

更新日期：2017-04-11 00:00:00

abstract：:Physical reservoir computing approaches have gained increased attention in recent years due to their potential for low-energy high-performance computing. Despite recent successes, there are bounds to what one can achieve simply by making physical reservoirs larger. Therefore, we argue that a switch from single-reservo...

journal_title：Scientific reports

authors： Freiberger M,Bienstman P,Dambre J

更新日期：2020-09-02 00:00:00

abstract：:The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...

journal_title：Scientific reports

authors： Asada R,Kanemoto S,Matsuhisa K,Hino K,Cui M,Cui X,Kaneko M,Imaizumi K

更新日期：2015-11-16 00:00:00

abstract：:The prediction of infarction volume after stroke onset depends on the shape of the growth dynamics of the infarction. To understand growth patterns that predict lesion volume changes, we studied currently available models described in literature and compared the models with Adaptive Neuro-Fuzzy Inference System [ANFIS...

journal_title：Scientific reports

authors： Kamran S,Akhtar N,Alboudi A,Kamran K,Ahmad A,Inshasi J,Salam A,Shuaib A,Qidwai U

更新日期：2017-08-08 00:00:00

abstract：:The recent combination of ultra-intense lasers and laser-accelerated electron beams is enabling the development of a new generation of compact x-ray light sources, the coherence of which depends directly on electron beam emittance. Although the emittance of accelerated electron beams can be low, it can grow due to the...

journal_title：Scientific reports

authors： Golovin G,Banerjee S,Liu C,Chen S,Zhang J,Zhao B,Zhang P,Veale M,Wilson M,Seller P,Umstadter D

更新日期：2016-04-19 00:00:00

abstract：:An individual's immune system is driven by both genetic and environmental factors that vary over time. To better understand the temporal and inter-individual variability of gene expression within distinct immune cell types, we developed a platform that leverages multiplexed single-cell sequencing and out-of-clinic cap...

journal_title：Scientific reports

authors： Dobreva T,Brown D,Park JH,Thomson M

更新日期：2020-11-25 00:00:00

abstract：:Complex associations exist between inflammation and thrombosis, with the inflammatory state tending to promote coagulation. Fibrinogen, an acute phase protein, has been shown to interact with the amyloidogenic ß-amyloid protein of Alzheimer's disease. However, little is known about the association between fibrinogen a...

journal_title：Scientific reports

authors： Page MJ,Thomson GJA,Nunes JM,Engelbrecht AM,Nell TA,de Villiers WJS,de Beer MC,Engelbrecht L,Kell DB,Pretorius E

更新日期：2019-02-28 00:00:00

abstract：:Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists for calling locus-specific amplifications and deletions in each patient sample. Here, we report the correlative analysis of copy number amplitude and length wi...

journal_title：Scientific reports

authors： Roszik J,Wu CJ,Siroy AE,Lazar AJ,Davies MA,Woodman SE,Kwong LN

更新日期：2016-01-20 00:00:00