Author Correction: 3D Printed Polyvinyl Alcohol Tablets with Multiple Release Profiles.

abstract：:Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...

journal_title：Scientific reports

authors： Zingerman B,Ziv D,Feder Krengel N,Korzets A,Matok I

更新日期：2020-11-13 00:00:00

abstract：:The development of new anode materials having high electrochemical performances and interesting reaction mechanisms is highly required to satisfy the need for long-lasting mobile electronic devices and electric vehicles. Here, we report a layer crystalline structured SnP3 and its unique electrochemical behaviors with ...

journal_title：Scientific reports

authors： Park JW,Park CM

更新日期：2016-10-24 00:00:00

abstract：:Optical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometry alone, and is thu...

journal_title：Scientific reports

authors： Ghimire A,Shafran E,Gerton JM

更新日期：2014-09-24 00:00:00

abstract：:Little-Parks effect names the oscillations in the superconducting critical temperature as a function of the magnetic field. This effect is related to the geometry of the sample. In this work, we show that this effect can be enhanced and manipulated by the inclusion of magnetic nanostructures with perpendicular magneti...

journal_title：Scientific reports

authors： de Ory MC,Rollano V,Gomez A,Menghini M,Muñoz-Noval A,Gonzalez EM,Vicent JL

更新日期：2020-06-25 00:00:00

abstract：:High-throughput screening facilities do not generally support biosafety level 3 organisms such as Mycobacterium tuberculosis. To discover not only antibacterials, but also virulence inhibitors with either bacterial or host cell targets, an assay monitoring lung fibroblast survival upon infection was developed and opti...

journal_title：Scientific reports

authors： Tükenmez H,Edström I,Ummanni R,Fick SB,Sundin C,Elofsson M,Larsson C

更新日期：2019-01-10 00:00:00

abstract：:Orb2 is a functional amyloid that plays a key role in Drosophila long-term memory formation. Orb2 has two isoforms that differ in their N-termini. The N-terminus of the A isoform (Orb2A) that precedes its Q-rich prion-like domain has been shown to be important for Orb2 aggregation and long-term memory. However, beside...

journal_title：Scientific reports

authors： Cervantes SA,Bajakian TH,Soria MA,Falk AS,Service RJ,Langen R,Siemer AB

更新日期：2016-12-06 00:00:00

abstract：:Levels of neutral poly-/perfluoroalkyl substances (nPFASs) in air and snow collected from Ny-Ålesund were measured and their air-snow exchange was determined to investigate whether they could re-volatilize into the atmosphere driven by means of air-snow exchange. The total concentration of 12 neutral PFASs ranged from...

journal_title：Scientific reports

authors： Xie Z,Wang Z,Mi W,Möller A,Wolschke H,Ebinghaus R

更新日期：2015-03-09 00:00:00

abstract：:Caffeine modifies vascular/cardiac contractility. Embryonic exposure to caffeine altered cardiac functions in offspring. This study determined chronic influence of prenatal caffeine on vessel functions in offspring. Pregnant Sprague-Dawley rats (5-month-old) were exposed to high dose of caffeine, their offspring (5-mo...

journal_title：Scientific reports

authors： Li N,Li Y,Gao Q,Li D,Tang J,Sun M,Zhang P,Liu B,Mao C,Xu Z

更新日期：2015-08-17 00:00:00

abstract：:To meet the demand for detection of foreign genes in genetically modified (GM) sugarcane necessary for regulation of gene technology, an efficient method with high specificity and rapidity was developed for the cry1Ac gene, based on loop-mediated isothermal amplification (LAMP). A set of four primers was designed usin...

journal_title：Scientific reports

authors： Zhou D,Guo J,Xu L,Gao S,Lin Q,Wu Q,Wu L,Que Y

更新日期：2014-05-09 00:00:00

abstract：:Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic m...

journal_title：Scientific reports

authors： Moriguchi H,Zhang Y,Mihara M,Sato C

更新日期：2012-01-01 00:00:00

abstract：:This study was aimed to investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in patients with prostate cancer (PCa). A meta-analysis including 14 publications (15 cohorts) with 16,266 patients was performed to evaluate the association between NLR and overall survival (OS), progression-free survival...

journal_title：Scientific reports

authors： Gu X,Gao X,Li X,Qi X,Ma M,Qin S,Yu H,Sun S,Zhou D,Wang W

更新日期：2016-02-25 00:00:00

abstract：:We investigated the association between impulsivity related traits and BMI at the observational and genetic epidemiology level in a cross-sectional population of healthy young American-European adults. We studied 998 students and university staff of European ancestry recruited from Chicago (Illinois) and Athens (Georg...

journal_title：Scientific reports

authors： Meyre D,Mohamed S,Gray JC,Weafer J,MacKillop J,de Wit H

更新日期：2019-11-26 00:00:00

abstract：:The general model presented here for the formation of chromatin domains, LADs and TADs, is primarily based on the 3-D structures of the corresponding DNA sequences, the GC-poor and GC-rich isochores. Indeed, the low-heterogeneity GC-poor isochores locally are intrinsically stiff and curved because of the presence of i...

journal_title：Scientific reports

authors： Bernardi G

更新日期：2018-12-13 00:00:00

abstract：:Many scientists are seeking better therapies for treating fibromyalgia (FM) pain. We used a mouse model of FM to determine if ASIC3 and its relevant signaling pathway participated in FM pain. We demonstrated that FM-induced mechanical hyperalgesia was attenuated by electroacupuncture (EA). The decrease in fatigue-indu...

journal_title：Scientific reports

authors： Yen LT,Hsieh CL,Hsu HC,Lin YW

更新日期：2017-04-25 00:00:00

abstract：:The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice. Acute treatment (1...

journal_title：Scientific reports

authors： Kee AJ,Chagan J,Chan JY,Bryce NS,Lucas CA,Zeng J,Hook J,Treutlein H,Laybutt DR,Stehn JR,Gunning PW,Hardeman EC

更新日期：2018-03-15 00:00:00

abstract：:Somatic mutations of many cancer genes tend to co-occur (termed co-mutations) in certain patterns during tumor initiation and progression. However, the genetic and epigenetic mechanisms that contribute to the co-mutations of these cancer genes have yet to be explored. Here, we systematically investigated the associati...

journal_title：Scientific reports

authors： Shi Y,Su XB,He KY,Wu BH,Zhang BY,Han ZG

更新日期：2016-10-20 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...

journal_title：Scientific reports

authors： Duca F,Zotter-Tufaro C,Kammerlander AA,Aschauer S,Binder C,Mascherbauer J,Bonderman D

更新日期：2018-01-18 00:00:00

abstract：:The general disease burden associated with the restrictive spirometric pattern (RSP) is substantial. However, the impact of RSP by its severity on general health problems and quality of life has not been well elucidated. This study aimed to analyse nutrition, physical activity, and quality of life in subjects who part...

journal_title：Scientific reports

authors： Chung SJ,Kim HI,Yang B,Kim T,Sim YS,Kang HK,Kim SH,Yoon HJ,Choi H,Lee H

更新日期：2020-11-12 00:00:00

abstract：:As an important online information retaining and processing function, working memory plays critical roles in many other cognitive functions. Several long-term factors, such as age, addiction and diseases, have been affirmed to impair working memory, but whether or how the short-term factors, like painful stimuli or em...

journal_title：Scientific reports

authors： Chen M,Wang YZ,Ma CC,Li QZ,Zhou H,Fu J,Yang QQ,Zhang YM,Liu Y,Cao JL

更新日期：2017-07-03 00:00:00

abstract：:The geographic distribution of species depends on their relationships with climate and on the biotic interactions of the species. Ecological Niche Models (ENMs) mainly consider climatic variables only and may tend to overestimate these distributions, especially for species strongly restricted by biotic interactions. W...

journal_title：Scientific reports

authors： Flores-Tolentino M,García-Valdés R,Saénz-Romero C,Ávila-Díaz I,Paz H,Lopez-Toledo L

更新日期：2020-06-12 00:00:00

abstract：:The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreERT2; Ihhfl/fl mice. Ihhfl/fl mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties and Ihh pathway were analyzed at 1...

journal_title：Scientific reports

authors： Li S,Xiang C,Wei X,Li H,Li K,Sun X,Wang S,Zhang M,Deng J,Wang X,Li P,Li R,Zhang Y,Wei L

更新日期：2018-07-09 00:00:00

abstract：:Tyrosine kinase activity of the asymmetric EGFR homodimer is negatively regulated via ERK-mediated phosphorylation of Thr-669 in the juxtamembrane domain. In the present study, we investigated in human breast cancer cells whether a similar mechanism plays a role in the feedback regulation of the ErbB2/ErbB3 heterodime...

journal_title：Scientific reports

authors： Kawasaki Y,Sakimura A,Park CM,Tomaru R,Tanaka T,Ozawa T,Zhou Y,Narita K,Kishi H,Muraguchi A,Sakurai H

更新日期：2016-08-17 00:00:00

abstract：:Meaningful, reliable and valid mRNA expression analyses by real-time quantitative PCR (RT-qPCR) can only be achieved, if suitable reference genes are chosen for normalization and if appropriate RT-qPCR quality standards are met. Human periodontal ligament (hPDL) fibroblasts play a major mediating role in orthodontic t...

journal_title：Scientific reports

authors： Kirschneck C,Batschkus S,Proff P,Köstler J,Spanier G,Schröder A

更新日期：2017-11-07 00:00:00

abstract：:The purpose of this study was to find the circulating microRNAs (miRNAs) co-related with the severity of coronary artery calcification (CAC), and testify whether the selected miRNAs could reflect the obstructive coronary artery disease in symptomatic patients. Patients with chest pain and moderated risk for coronary a...

journal_title：Scientific reports

authors： Liu W,Ling S,Sun W,Liu T,Li Y,Zhong G,Zhao D,Zhang P,Song J,Jin X,Xu Z,Song H,Li Q,Liu S,Chai M,Dai Q,He Y,Fan Z,Zhou YJ,Li Y

更新日期：2015-11-05 00:00:00

abstract：:Fatty liver (FL) disease is the most common type of chronic liver disease. We hypothesized that liver's response to the process where large droplets of triglyceride fat accumulate in liver cells is reflected also in gene pathway expression in blood. Peripheral blood genome wide gene expression analysis and ultrasonic ...

journal_title：Scientific reports

authors： Taipale T,Seppälä I,Raitoharju E,Mononen N,Lyytikäinen LP,Illig T,Waldenberger M,Juonala M,Hutri-Kähönen N,Oksala N,Kähönen M,Raitakari O,Lehtimäki T

更新日期：2018-07-09 00:00:00

abstract：:The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neu...

journal_title：Scientific reports

authors： Awandare GA,Nyarko PB,Aniweh Y,Ayivor-Djanie R,Stoute JA

更新日期：2018-04-10 00:00:00

abstract：:Computed Tomography derived Fractional Flow Reserve (CTFFR) is an emerging non-invasive imaging modality to assess functional significance of coronary stenosis. We performed a meta-analysis to compare the diagnostic performance of CTFFR to invasive Fractional Flow reserve (FFR). Electronic search was performed to iden...

journal_title：Scientific reports

authors： Agasthi P,Kanmanthareddy A,Khalil C,Egbuche O,Yarlagadda V,Sachdeva R,Arsanjani R

更新日期：2018-08-01 00:00:00

abstract：:3β-Hydroxysteroid-Δ24 reductase (DHCR24), the final enzyme of the cholesterol biosynthetic pathway, has been associated with urogenital neoplasms. However, the function of DHCR24 in endometrial cancer (EC) remains largely elusive. Here, we analyzed the expression profile of DHCR24 and the progesterone receptor (PGR) i...

journal_title：Scientific reports

authors： Dai M,Zhu XL,Liu F,Xu QY,Ge QL,Jiang SH,Yang XM,Li J,Wang YH,Wu QK,Ai ZH,Teng YC,Zhang ZG

更新日期：2017-01-23 00:00:00

abstract：:The exponential growth in knowledge has resulted in a better understanding of the lactation process in a wide variety of animals. However, the underlying genetic mechanisms are not yet clearly known. In order to identify the mechanisms involved in the lactation process, various mehods, including meta-analysis, weighte...

journal_title：Scientific reports

authors： Farhadian M,Rafat SA,Panahi B,Mayack C

更新日期：2021-01-27 00:00:00

abstract：:Site variation in fixation, staining, and scanning can confound automated tissue based image classifiers for disease characterization. In this study we incorporated stability into four feature selection methods for identifying the most robust and discriminating features for two prostate histopathology classification t...

journal_title：Scientific reports

authors： Leo P,Elliott R,Shih NNC,Gupta S,Feldman M,Madabhushi A

更新日期：2018-10-08 00:00:00