Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.

abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...

journal_title：Scientific reports

authors： Dong C,An T,Zhu H,Wang J,Hu B,Jiang Y,Yang Y,Li J

更新日期：2020-01-31 00:00:00

abstract：:Knee osteoarthritis (KOA) is reported to have characteristic kinematics during walking. However, the relationship between Kellgren-Lawrence (K/L) score and the 3D kinematic gait of patients with medial KOA remains unclear. Here, ninety-seven patients with medial KOA and thirty-eight asymptomatic participants were invo...

journal_title：Scientific reports

authors： Zeng X,Ma L,Lin Z,Huang W,Huang Z,Zhang Y,Mao C

更新日期：2017-06-22 00:00:00

abstract：:The fabrication of Ru nanostructures by focused electron beam induced deposition (FEBID) requires suitable precursor molecules and processes to obtain the pure metal. So far this is problematic because established organometallic Ru precursors contain large organic ligands, such as cyclopentadienyl anions, that tend to...

journal_title：Scientific reports

authors： Rohdenburg M,Boeckers H,Brewer CR,McElwee-White L,Swiderek P

更新日期：2020-07-02 00:00:00

abstract：:Associated with global warming, drought has destructive influences on agriculture and ecosystems, especially in the fragile Qinghai-Tibet Plateau (QTP). This study investigated spatial-temporal patterns of meteorological drought in the QTP and its surrounding areas and made an attempt to explore the relationship betwe...

journal_title：Scientific reports

authors： Feng W,Lu H,Yao T,Yu Q

更新日期：2020-08-31 00:00:00

abstract：:Persistent human papillomavirus (HPV) infection is the vital factor driving cervical carcinogenesis; however, other features of the local cervicovaginal microenvironment (CVM) may play a critical role in development of precancerous cervical dysplasia and progression to invasive cervical carcinoma (ICC). Here we invest...

journal_title：Scientific reports

authors： Łaniewski P,Cui H,Roe DJ,Barnes D,Goulder A,Monk BJ,Greenspan DL,Chase DM,Herbst-Kralovetz MM

更新日期：2019-05-14 00:00:00

abstract：:Mass spectrometry (MS) for the detection of proteins is an indispensable tool for evaluating the biological processes of the proteome. Proteomics frequently requires proteolysis of proteins into peptide fragments. Proteins can be refractory to ideal proteolysis at the sequence level rendering them difficult to analyze...

journal_title：Scientific reports

authors： Reyna C,Mba Medie F,Champion MM,Champion PA

更新日期：2016-09-14 00:00:00

abstract：:Helicobacter pylori is presumed to infect gastric tissue via the oral cavity in childhood, whereas risk factors for H. pylori infection in the oral cavity are unknown. In this study, we analysed the effects of Streptococcus mutans, a major cariogenic bacterial species, on H. pylori colonisation in the oral cavity, as ...

journal_title：Scientific reports

authors： Nomura R,Kadota T,Ogaya Y,Matayoshi S,Iwashita N,Okawa R,Nakano K

更新日期：2020-07-27 00:00:00

abstract：:The absorption spectra in array of Ge, Al and Ge/Al-shell nanoparticles immersed in alumina (Al2O3) matrix is calculated in framework of ab initio macroscopic dielectric model. It is demonstrated that absorption is strongly enhanced when germanium nanospheres are encapsulated by Al-shell. Two absorption peaks, appeari...

journal_title：Scientific reports

authors： Despoja V,Basioli L,Parramon JS,Mičetić M

更新日期：2020-01-09 00:00:00

abstract：:Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signaling, biofilm formation, and stress responses. Here, the effects of abiotic stressors on OMV contents and composition from biofilm cells of the plant health-promoting bacterium Pseudomonas chlororaphis O6 (PcO6) are exami...

journal_title：Scientific reports

authors： Potter M,Hanson C,Anderson AJ,Vargis E,Britt DW

更新日期：2020-12-04 00:00:00

abstract：:Given that observational associations may be inaccurate, we used offspring blood pressure (BP) to provide alternative estimates of the associations between own BP and mortality. Observational associations between BP and mortality, estimated as hazard ratios (HRs) from Cox regression, were compared to HRs obtained usin...

journal_title：Scientific reports

authors： Wade KH,Carslake D,Nilsen TI,Timpson NJ,Davey Smith G,Romundstad P

更新日期：2015-07-22 00:00:00

abstract：:The immune system is constantly challenged, being required to protect the organism against a wide variety of infectious pathogens and, at the same time, to avoid autoimmune disorders. One of the most important molecules involved in these events is the Major Histocompatibility Complex class I (MHC-I), responsible for b...

journal_title：Scientific reports

authors： Rigo MM,Antunes DA,Vaz de Freitas M,Fabiano de Almeida Mendes M,Meira L,Sinigaglia M,Vieira GF

更新日期：2015-12-17 00:00:00

abstract：:We present the design and performance characterization of a Faraday laser directly lasing on the Rb 1529 nm transition (Rb, 5P 3/2 - 4D 5/2) with high stability, narrow spectral linewidth and low cost. This system does not need an additional frequency-stabilized pump laser as a prerequisite to preparing Rb atom from 5...

journal_title：Scientific reports

authors： Chang P,Peng H,Zhang S,Chen Z,Luo B,Chen J,Guo H

更新日期：2017-08-21 00:00:00

abstract：:The ability to accurately forecast seizures could significantly improve the quality of life of patients with drug-refractory epilepsy. Prediction capabilities rely on the adequate identification of seizure activity precursors from electroencephalography recordings. Although a long list of features has been proposed, n...

journal_title：Scientific reports

authors： Bou Assi E,Gagliano L,Rihana S,Nguyen DK,Sawan M

更新日期：2018-10-19 00:00:00

abstract：:We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...

journal_title：Scientific reports

authors： Xue VW,Cheung MT,Chan PT,Luk LLY,Lee VH,Au TC,Yu AC,Cho WCS,Tsang HFA,Chan AK,Wong SCC

更新日期：2019-09-10 00:00:00

abstract：:Large-scale anthropogenic disturbances can have direct and indirect effects on marine communities, with direct effects often taking the form of widespread injury or mortality and indirect effects manifesting as changes in food web structure. Here, we report a time series that captures both direct and indirect effects ...

journal_title：Scientific reports

authors： Lewis JP,Tarnecki JH,Garner SB,Chagaris DD,Patterson WF 3rd

更新日期：2020-04-09 00:00:00

abstract：:Increasingly, biofilms are being recognised for their causative role in persistent infections (like cystic fibrosis, otitis media, diabetic foot ulcers) and nosocomial diseases (biofilm-infected vascular catheters, implants and prosthetics). Given the clinical relevance of biofilms and their recalcitrance to conventio...

journal_title：Scientific reports

authors： Sharma A,Gupta P,Kumar R,Bhardwaj A

更新日期：2016-02-25 00:00:00

abstract：:This article presents the homodyne detection in a self-oscillation system, which represented by a short-range radar (SRR) circuit, that is analysed using a multi-time forced oscillator (MTFO) model. The MTFO model is based on a forced oscillation perspective with the signal and system theory, a second-order differenti...

journal_title：Scientific reports

authors： Kittipute K,Saratayon P,Srisook S,Wardkein P

更新日期：2017-03-02 00:00:00

abstract：:This research investigates the applicability of an ANN and genetic algorithms for modeling and multiobjective optimization of the thermal conductivity and viscosity of water-based spinel-type MnFe2O4 nanofluid. Levenberg-Marquardt, quasi-Newton, and resilient backpropagation methods are employed to train the ANN. The ...

journal_title：Scientific reports

authors： Amani M,Amani P,Kasaeian A,Mahian O,Pop I,Wongwises S

更新日期：2017-12-12 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, whole-transcriptome analysis was performed in 3 pairs of colorectal cancer (CRC) and matched normal mucosa (NM) by RNA sequencing (RNA-seq). Fol...

journal_title：Scientific reports

authors： Yamada A,Yu P,Lin W,Okugawa Y,Boland CR,Goel A

更新日期：2018-01-12 00:00:00

abstract：:In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...

journal_title：Scientific reports

authors： Giddey AD,de Kock E,Nakedi KC,Garnett S,Nel AJ,Soares NC,Blackburn JM

更新日期：2017-03-06 00:00:00

abstract：:Keratoconus is a common degenerative corneal disease that can lead to significant visual morbidity, and both genetic and environmental factors have been implicated in its pathogenesis. We compared the transcriptome of keratoconus and control epithelium using RNA-Seq. Epithelial tissues were obtained prior to surgery f...

journal_title：Scientific reports

authors： You J,Corley SM,Wen L,Hodge C,Höllhumer R,Madigan MC,Wilkins MR,Sutton G

更新日期：2018-01-10 00:00:00

abstract：:Behavioral alterations emerging after central or peripheral vision loss suggest that cerebral reorganization occurs for both the afferented and deafferented early visual cortex (EVC). We explored the functional reorganization of the central and peripheral EVC following visual field defects specifically affecting centr...

journal_title：Scientific reports

authors： Sabbah N,Sanda N,Authié CN,Mohand-Saïd S,Sahel JA,Habas C,Amedi A,Safran AB

更新日期：2017-02-24 00:00:00

abstract：:During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial lymphatic capillary bed is expanding during plaque development in humans and mouse models of atherosclerosis....

journal_title：Scientific reports

authors： Rademakers T,van der Vorst EP,Daissormont IT,Otten JJ,Theodorou K,Theelen TL,Gijbels M,Anisimov A,Nurmi H,Lindeman JH,Schober A,Heeneman S,Alitalo K,Biessen EA

更新日期：2017-03-28 00:00:00

abstract：:Light, as the energy source in photosynthesis, is essential for plant growth and development. Extended darkness causes dramatic gene expression changes. In this study, we applied DNase-seq (DNase I hypersensitive site sequencing) to study changes of chromatin accessibility in euchromatic and heterochromatic regions un...

journal_title：Scientific reports

authors： Liu Y,Zhang W,Zhang K,You Q,Yan H,Jiao Y,Jiang J,Xu W,Su Z

更新日期：2017-06-22 00:00:00

abstract：:Glutamine (Gln) is converted to excitatory (glutamate, aspartate) and inhibitory (γ-amino butyric acid) amino acid neurotransmitters in brain, and is a source of energy during glucose deprivation. Current research utilized an Analytical Quality by Design approach to optimize levels and combinations of critical gas pre...

journal_title：Scientific reports

authors： Bheemanapally K,Ibrahim MMH,Briski KP

更新日期：2020-04-28 00:00:00

abstract：:The reliable identification of diffuse large B-cell lymphoma (DLBCL)-specific targets owns huge implications for its diagnosis and treatment. Long non-coding RNAs (lncRNAs) are implicated in DLBCL pathogenesis; however, circulating DLBCL-related lncRNAs are barely investigated. We investigated plasma lncRNAs; HOTAIR, ...

journal_title：Scientific reports

authors： Senousy MA,El-Abd AM,Abdel-Malek RR,Rizk SM

更新日期：2021-01-22 00:00:00

abstract：:Porous materials display enhanced scattering mechanisms that greatly influence their transport properties. Metal-assisted chemical etching (MACE) enables fabrication of porous silicon nanowires starting from a doped Si wafer by using a metal template that catalyzes the etching process. Here, we report on the low therm...

journal_title：Scientific reports

authors： Ferrando-Villalba P,D'Ortenzi L,Dalkiranis GG,Cara E,Lopeandia AF,Abad L,Rurali R,Cartoixà X,De Leo N,Saghi Z,Jacob M,Gambacorti N,Boarino L,Rodríguez-Viejo J

更新日期：2018-08-24 00:00:00

abstract：:It has been well established that some Armillaria species are symbionts of Polyporus umbellatus, However, little is known about the evolutionary history of P. umbellatus-Armillaria associations. In this research, we used an analysis based on the strength of the phylogenetic signal to investigate P. umbellatus-Armillar...

journal_title：Scientific reports

authors： Xing X,Men J,Guo S

更新日期：2017-06-26 00:00:00

abstract：:Although early diagnosis and treatment reduce the risk of blindness from glaucoma, the decision on whether or not to begin treatment in patients with suspected glaucoma is often a dilemma because the majority of patients never develop definite glaucoma. A growing body of evidences suggests that posterior bowing of the...

journal_title：Scientific reports

authors： Kim JA,Kim TW,Weinreb RN,Lee EJ,Girard MJA,Mari JM

更新日期：2018-01-15 00:00:00

abstract：:Selective norepinephrine reuptake inhibitors (sNRIs) provide an effective class of approved antipsychotics, whose inhibitory mechanism could facilitate the discovery of privileged scaffolds with enhanced drug efficacy. However, the crystal structure of human norepinephrine transporter (hNET) has not been determined ye...

journal_title：Scientific reports

authors： Zheng G,Xue W,Wang P,Yang F,Li B,Li X,Li Y,Yao X,Zhu F

更新日期：2016-05-27 00:00:00