Abstract：
:The ability to accurately forecast seizures could significantly improve the quality of life of patients with drug-refractory epilepsy. Prediction capabilities rely on the adequate identification of seizure activity precursors from electroencephalography recordings. Although a long list of features has been proposed, none of these is able to independently characterize the brain states during transition to a seizure. This work assessed the feasibility of using the bispectrum, an advanced signal processing technique based on higher order statistics, as a precursor of seizure activity. Quantitative features were extracted from the bispectrum and passed through two statistical tests to check for significant differences between preictal and interictal recordings. Results showed statistically significant differences (p < 0.05) between preictal and interictal states using all bispectrum-extracted features. We used normalized bispectral entropy, normalized bispectral squared entropy, and mean of magnitude as inputs to a 5-layer multilayer perceptron classifier and achieved respective held-out test accuracies of 78.11%, 72.64%, and 73.26%.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Bou Assi E,Gagliano L,Rihana S,Nguyen DK,Sawan Mdoi
10.1038/s41598-018-33969-9subject
Has Abstractpub_date
2018-10-19 00:00:00pages
15491issue
1issn
2045-2322pii
10.1038/s41598-018-33969-9journal_volume
8pub_type
杂志文章abstract：:Plasmodiophora brassicae causes clubroot disease in cruciferous. In this report, lipid droplets were observed in the resting spores of P. brassicae. 295 lipid droplet-associated proteins were identified and categorized into nine groups. Transcriptome analysis of these proteins during three different zoosporic stages r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36965
更新日期：2016-11-22 00:00:00
abstract：:Recent studies suggest a functional involvement of Epithelial-Mesenchymal Transition (EMT) in tumor chemoresistance. Specifically, EMT is associated with chemoresistance and poor prognosis in triple-negative breast cancer. However, no effective therapy targeting EMT has been developed. Here, we report that periostin, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22340-7
更新日期：2018-03-05 00:00:00
abstract：:A great deal of attention has been recently focused on Electrochromic (EC) materials and EC based devices, promoting mainly applications related to display technology. In this case, EC based displays are usually actuated by the application of low dc bias voltages, changing their appearance from transparent to opaque. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28839
更新日期：2016-06-30 00:00:00
abstract：:Prenatal skeletal muscle development genetically determines postnatal muscle characteristics such as growth and meat quality in pigs. However, the molecular mechanisms underlying prenatal skeletal muscle development remain unclear. Here, we performed the first genome-wide analysis of chimeric RNAs, single nuclear poly...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29039
更新日期：2016-06-29 00:00:00
abstract：:Gold standard quantitative nucleic acid tests for diagnosis of viral diseases are currently limited to implementation in laboratories outside of the clinic. An instrument for conducting nucleic acid testing at the point-of-care (POC) that is easily operable by the clinician would reduce the required number of visits t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28124-3
更新日期：2018-06-28 00:00:00
abstract：:Almost 150 years after the first identification of Neandertal skeletal material, the cognitive and symbolic abilities of these populations remain a subject of intense debate. We present 99 new Neandertal remains from the Troisième caverne of Goyet (Belgium) dated to 40,500-45,500 calBP. The remains were identified thr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29005
更新日期：2016-07-06 00:00:00
abstract：:Crystal and electronic structures of ~380 nm BiFeO3 film grown on LaAlO3 substrate are comprehensively studied using advanced transmission electron microscopy (TEM) technique combined with first-principles theory. Cross-sectional TEM images reveal the BiFeO3 film consists of two zones with different crystal structures...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46498
更新日期：2017-04-19 00:00:00
abstract：:The aim of this study was to investigate rheumatoid arthritis (RA), and systemic lupus erythematous (SLE) as risk factors for stroke. The study was analyzed by Using the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005), this cohort study investigated patients with a recorded diagnosis of RA (N = 6114), an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05110
更新日期：2014-06-05 00:00:00
abstract：:The study aimed at investigating the extent to which the brain adaptively exploits or compensates interaction torque (IT) during movement control in various velocity and load conditions. Participants performed arm pointing movements toward a horizontal plane without a prescribed reach endpoint at slow, neutral and rap...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38845
更新日期：2016-12-12 00:00:00
abstract：:Leucine-rich repeat kinase 2 (LRRK2) is a promising therapeutic target for the treatment of Parkinson's disease (PD) and LRRK2 kinase inhibitors are currently being tested in early phase clinical trials. In order to ensure the highest chance of success, a biomarker-guided entry into clinical trials is key. LRRK2 phosp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74195-6
更新日期：2020-10-14 00:00:00
abstract：:The d-band center model of Hammer and Nørskov is widely used in understanding and predicting catalytic activity on transition metal (TM) surfaces. Here, we demonstrate that this model is inadequate for capturing the complete catalytic activity of the magnetically polarized TM surfaces and propose its generalization. W...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35916
更新日期：2016-11-03 00:00:00
abstract：:Light-sheet microscopy enables considerable speed and phototoxicity gains, while quantitative-phase imaging confers label-free recognition of cells and organelles, and quantifies their number-density that, thermodynamically, is more representative of metabolism than size. Here, we report the fusion of these two imagin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76730-x
更新日期：2020-11-19 00:00:00
abstract：:Muscular dystrophy-dystroglycanopathies comprise a heterogeneous and complex group of disorders caused by loss-of-function mutations in a multitude of genes that disrupt the glycobiology of α-dystroglycan, thereby affecting its ability to function as a receptor for extracellular matrix proteins. Of the various genes i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46431-1
更新日期：2019-07-11 00:00:00
abstract：:Arthroplasty is a surgical procedure to restore the function of the joint of patient suffering from knee osteoarthritis. However, postoperative functional deficits are reported even after a rehabilitation program. In order to determine the origin of functional deficits of patient suffering from knee osteoarthritis and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62146-0
更新日期：2020-03-24 00:00:00
abstract：:One-year time series of current velocities and hydrographic parameters based on four deep moorings deployed east of the Luzon Strait are employed to study the deep current at the western boundary (DCWB) of the northern Philippine Basin. While the mean current is relatively weak, the DCWB is highly variable on an intra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32541-9
更新日期：2018-09-25 00:00:00
abstract：:There are approximately 1 million cryptococcal infections per year among HIV+ individuals, resulting in nearly 625,000 deaths. Cryptococcus neoformans and Cryptococcus gattii are the two most common species that cause human cryptococcosis. These two species of Cryptococcus have differences in pathogenicity, diagnosis,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68978-0
更新日期：2020-07-27 00:00:00
abstract：:Improving surface sensitivities of nanostructure-based plasmonic sensors is an important issue to be addressed. Among the SPR measurements, the wavelength interrogation is commonly utilized. We proposed using blue-shifted surface plasmon mode and Fano resonance, caused by the coupling of a cavity mode (angle-independe...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28122-5
更新日期：2018-06-27 00:00:00
abstract：:Hand size perceptual distortions characterize adult human cognition. Notwithstanding the importance of uncovering how hand size representation develops in humans, studies in this field are still at a preliminary stage. Indeed, it is yet to be understood whether hand size distortions are present and reliable in early c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62206-5
更新日期：2020-03-25 00:00:00
abstract：:Higher and lower levels of alertness typically lead to a leftward and rightward bias in attention, respectively. This relationship between alertness and spatial attention potentially has major implications for health and safety. The current study examined alertness and spatial attention under simulated shiftworking co...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-020-71800-6
更新日期：2020-09-11 00:00:00
abstract：:Stroke is one of the main causes of human disabilities. Experimental observations indicate that several mechanisms are activated during the recovery of functional activity after a stroke. Here we unveil how the brain recovers by explaining the role played by three mechanisms: Plastic adaptation, hyperexcitability and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50946-y
更新日期：2019-11-01 00:00:00
abstract：:Shortest paths are not always simple. In planar networks, they can be very different from those with the smallest number of turns--the simplest paths. The statistical comparison of the lengths of the shortest and simplest paths provides a non trivial and non local information about the spatial organization of these gr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03495
更新日期：2013-12-13 00:00:00
abstract：:Brønsted-Lewis acidic ionic liquids (ILs) were applied to catalyze cellobiose to prepare levulinic acid (LA) in one pot under hydrothermal conditions. Under the optimum conditions, the highest LA yield of 67.51% was obtained when low [HO3S-(CH2)3-mim]Cl-FeCl3 (molar fraction of FeCl3 x = 0.60) was used. This indicated...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38051-y
更新日期：2019-02-12 00:00:00
abstract：:Cervical sagittal alignment is considered to have a special role in the pathogenesis and evaluation of cervical diseases. Previous studies have demonstrated that cervical sagittal alignment is correlated with thoracolumbar and pelvic alignments. As the direct anatomical structures connect to the cervical region, howev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33287-0
更新日期：2018-10-18 00:00:00
abstract：:Recently, some very tight constraints of annihilating dark matter have been obtained from gamma-ray data of the Milky Way and Milky Way dwarf spheroidal satellite galaxies. In this article, we report that there are two excellent galaxy clusters (A2877 and Fornax) which can provide interesting constraints for annihilat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14950-4
更新日期：2017-11-02 00:00:00
abstract：:Volatile organic compounds (VOCs) represent a broad class of chemicals, many of which can be found in indoor air including residential indoor air. VOCs derive from a variety of sources including cleaning products, cooking practices, fragrances and fresheners, hobbies and at-home work behaviors. This study examined res...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78756-7
更新日期：2020-12-10 00:00:00
abstract：:Many species can successfully colonize new areas despite their propagules having low genetic variation. We assessed whether the decreased genetic diversity could result in temporal fluctuations of genetic parameters of the new populations of an invasive species, western flower thrips, Frankliniella occidentalis, using...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11877
更新日期：2015-07-03 00:00:00
abstract：:Nitrate treatment has been widely used in various seawater injection projects to treat biologic sulfate reduction or reservoir souring. To design a promising nitrate treatment plan, it is essential to have a comprehensive understanding of reactions that represent the microbial communities of the reservoir and mechanis...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44033-5
更新日期：2019-05-17 00:00:00
abstract：:Functional integrity of eukaryotic organelles relies on direct physical contacts between distinct organelles. However, the entity of organelle-tethering factors is not well understood due to lack of means to analyze inter-organelle interactions in living cells. Here we evaluate the split-GFP system for visualizing org...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24466-0
更新日期：2018-04-18 00:00:00
abstract：:Recent longitudinal neuroimaging and neurophysiological studies have shown that tracking relative age-related changes in neural signals, rather than a static snapshot of a neural measure, could offer higher sensitivity for discriminating typically developing (TD) individuals from those with autism spectrum disorder (A...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67507-3
更新日期：2020-07-06 00:00:00
abstract：:Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified b...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11486-5
更新日期：2017-09-07 00:00:00
