Abstract：
:Directional transport of auxin is essential for plant development, with PIN auxin transport proteins representing an integral part of the machinery that controls hormone distribution. However, unlike the rapidly emerging framework of molecular determinants regulating PIN protein abundance and subcellular localization, insights into mechanisms controlling PIN transcription are still limited. Here we describe PIN2 PROMOTER BINDING PROTEIN 1 (PPP1), an evolutionary conserved plant-specific DNA binding protein that acts on transcription of PIN genes. Consistent with PPP1 DNA-binding activity, PPP1 reporter proteins are nuclear localized and analysis of PPP1 null alleles and knockdown lines indicated a function as a positive regulator of PIN expression. Furthermore, we show that ppp1 pleiotropic mutant phenotypes are partially reverted by PIN overexpression, and results are presented that underline a role of PPP1-PIN promoter interaction in PIN expression control. Collectively, our findings identify an elementary, thus far unknown, plant-specific DNA-binding protein required for post-embryonic plant development, in general, and correct expression of PIN genes, in particular.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Benjamins R,Barbez E,Ortbauer M,Terpstra I,Lucyshyn D,Moulinier-Anzola J,Khan MA,Leitner J,Malenica N,Butt H,Korbei B,Scheres B,Kleine-Vehn J,Luschnig Cdoi
10.1038/srep32196subject
Has Abstractpub_date
2016-08-24 00:00:00pages
32196issn
2045-2322pii
srep32196journal_volume
6pub_type
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