Quantifying cadherin mechanotransduction machinery assembly/disassembly dynamics using fluorescence covariance analysis.

abstract：:Studies of locomotor activity in Svalbard reindeer reported the temporary absence of diel rhythms under Arctic photic conditions. However, using Lomb-Scargle periodogram analyses with high statistical power we found diel or circadian rhythmicity throughout the entire year in measures of behaviour, temperature in the r...

journal_title：Scientific reports

authors： Arnold W,Ruf T,Loe LE,Irvine RJ,Ropstad E,Veiberg V,Albon SD

更新日期：2018-09-27 00:00:00

abstract：:Since 2013, the outbreak or sporadic infection of a new reassortant H7N9 influenza virus in China has resulted in hundreds of deaths and thousands of illnesses. An H7N9 vaccine is urgently needed, as a licensed human vaccine against H7N9 influenza is currently not available. Here, we developed a recombinant adenovirus...

journal_title：Scientific reports

authors： Wang X,Fu W,Yuan S,Yang X,Song Y,Liu L,Chi Y,Cheng T,Xing M,Zhang Y,Zhang C,Yang Y,Zhu C,Zhang X,Xiong S,Xu J,Zhou D

更新日期：2017-05-12 00:00:00

abstract：:This study aimed to examine the effect of transcutaneous electrical nerve stimulation (TENS) on stair climbing capacity in individuals with pre-radiographic to mild knee osteoarthritis (OA). This is a secondary analysis of data from a single, participant-blinded, randomized controlled trial with a pre-post design. Par...

journal_title：Scientific reports

authors： Iijima H,Eguchi R,Shimoura K,Yamada K,Aoyama T,Takahashi M

更新日期：2020-04-29 00:00:00

abstract：:Close contacts between the endoplasmic reticulum membrane and the mitochondrial outer membrane facilitate efficient transfer of lipids between the organelles and coordinate Ca2+ signalling and stress responses. Changes to this coupling is associated with a number of metabolic disorders and neurodegenerative diseases i...

journal_title：Scientific reports

authors： Harmon M,Larkman P,Hardingham G,Jackson M,Skehel P

更新日期：2017-12-12 00:00:00

abstract：:Cytological and molecular studies have revealed that inversion chromosomal polymorphism is widespread across taxa and that inversions are among the most common structural changes fixed between species. Two major mechanisms have been proposed for the origin of inversions considering that breaks occur at either repetiti...

journal_title：Scientific reports

authors： Orengo DJ,Puerma E,Cereijo U,Aguadé M

更新日期：2019-11-18 00:00:00

abstract：:Soil components (e.g., clays, bacteria and humic substances) are known to produce mineral-organic composites in natural systems. Herein, batch sorption isotherms, isothermal titration calorimetry (ITC), and Cd K-edge EXAFS spectroscopy were applied to investigate the binding characteristics of Cd on montmorillonite(Mo...

journal_title：Scientific reports

authors： Du H,Chen W,Cai P,Rong X,Dai K,Peacock CL,Huang Q

更新日期：2016-01-21 00:00:00

abstract：:Controlling thickness and tightness of surface passivation shells is crucial for many applications of core-shell nanoparticles (NP). Usually, to determine shell thickness, core and core/shell particle are measured individually requiring the availability of both nanoobjects. This is often not fulfilled for functional n...

journal_title：Scientific reports

authors： Weigert F,Müller A,Häusler I,Geißler D,Skroblin D,Krumrey M,Unger W,Radnik J,Resch-Genger U

更新日期：2020-11-26 00:00:00

abstract：:Trees produce pollen during specific times of the year. Pollen can induce pollinosis, a type of allergic rhinitis, in humans. In Japan, allergenic pollen is mainly dispersed from February to May. Using data collected at 120 observation sites managed by the Japanese Ministry of the Environment, we studied the annual pa...

journal_title：Scientific reports

authors： Ishibashi A,Sakai K

更新日期：2019-08-07 00:00:00

abstract：:Chronic kidney disease (CKD) progresses to end-stage renal failure via renal tubulointerstitial fibrosis. Malnutrition, inflammation, and arteriosclerosis interact to exacerbate the poor prognosis of CKD, and their effective management is thus essential. The traditional Japanese medicine Rikkunshito (RKT) exerts appet...

journal_title：Scientific reports

authors： Wakui H,Yamaji T,Azushima K,Uneda K,Haruhara K,Nakamura A,Ohki K,Kinguchi S,Kobayashi R,Urate S,Suzuki T,Kamimura D,Minegishi S,Ishigami T,Kanaoka T,Matsuo K,Miyazaki T,Fujikawa T,Yamashita A,Tamura K

更新日期：2020-02-05 00:00:00

abstract：:This study is to investigate the frequencies of T-helper (Th)22, Th17 and Th1 cells and the levels of related cytokines in subchondral bone marrow in patients with rheumatoid arthritis (RA). Bone marrow and peripheral blood samples were collected from RA, osteoarthritis (OA) patients and healthy controls. The frequenc...

journal_title：Scientific reports

authors： Li S,Yin H,Zhang K,Wang T,Yang Y,Liu X,Chang X,Zhang M,Yan X,Ren Y,Pan W,Zhang L

更新日期：2017-07-06 00:00:00

abstract：:We report the thermal annealing-induced formation of ring-like structure of Zn(II)-doped magnetite from iron alkoxide leaf-like nanoplate precusor. The phase, structure and morphology of magnetite nanorings were comprehensively characterized by powder X-ray diffraction, X-ray photoelectron spectroscopy, atomic force m...

journal_title：Scientific reports

authors： Yang S,Jiang JT,Xu CY,Wang Y,Xu YY,Cao L,Zhen L

更新日期：2017-04-03 00:00:00

abstract：:Shigella spp., emerging from multiple origins of Escherichia coli, poses a significant health threat as a causative agent of bacillary dysentery. While multiple serotypes of four different species have evolved via independent lineages, Shigella spp. are designated as a single pathotype, primarily because of their comm...

journal_title：Scientific reports

authors： Thomas AK,Preetha S,Omanakuttan A,Vidyullata L,Ashokan A,Rajachandran V,Chattopadhyay S

更新日期：2019-03-01 00:00:00

abstract：:Anxiety and depression are commonly found in patients with diabetes, but little is known about how the anxiety and depression symptoms of diabetes patients and the health-related quality of life (HRQoL) over time influence each other. Therefore, we conducted a survey among patients with diabetes (T1) and repeated the ...

journal_title：Scientific reports

authors： Liu X,Haagsma J,Sijbrands E,Buijks H,Boogaard L,Mackenbach JP,Erasmus V,Polinder S

更新日期：2020-05-20 00:00:00

abstract：:Most pancreatic cancer (PC) patients manifest multiple liver metastases at the time of diagnosis. Activated platelets play a key role in tumor growth and tumor metastases. Mean platelet volume (MPV) is a platelet index and is altered in patients with malignancies. This study aimed to evaluate whether MPV can effective...

journal_title：Scientific reports

authors： Yin JB,Wang X,Zhang X,Liu L,Wang RT

更新日期：2018-04-16 00:00:00

abstract：:The ability to rapidly assess the efficacy of therapeutic strategies for incurable bone metastatic prostate cancer is an urgent need. Pre-clinical in vivo models are limited in their ability to define the temporal effects of therapies on simultaneous multicellular interactions in the cancer-bone microenvironment. Inte...

journal_title：Scientific reports

authors： Cook LM,Araujo A,Pow-Sang JM,Budzevich MM,Basanta D,Lynch CC

更新日期：2016-07-14 00:00:00

abstract：:We have designed a fully automated optical microscope running at high-speed and achieving a very high spatial resolution. In order to overcome the resolution limit of optical microscopes, it exploits the localized surface plasmon resonance phenomenon. The customized setup using a polarization analyzer, based on liquid...

journal_title：Scientific reports

authors： Alexandrov A,Asada T,De Lellis G,Di Crescenzo A,Gentile V,Naka T,Tioukov V,Umemoto A

更新日期：2020-11-02 00:00:00

abstract：:During infection with non-enveloped viruses, antibodies stimulate immunity from inside cells by activating the cytosolic Fc receptor TRIM21. This intracellular humoral response relies on opsonized viral particles reaching the cytosol intact but the antigenic and kinetic constraints involved are unknown. We have solved...

journal_title：Scientific reports

authors： Bottermann M,Lode HE,Watkinson RE,Foss S,Sandlie I,Andersen JT,James LC

更新日期：2016-11-24 00:00:00

abstract：:The existing molecular cloning methods are often limited by the availability of suitable restriction sites. It is still a challenge for simultaneous cloning of multiple fragments into different sites of a single vector. Here we developed a novel method named improved overlap extension PCR (IOEP) for restriction enzyme...

journal_title：Scientific reports

authors： Guo W,Xie B,Jiang M,Zhu XJ,Qiu M,Dai ZM

更新日期：2019-10-30 00:00:00

abstract：:Povidone-iodine (PVI) is principally used as an antimicrobial agent. It has been found that 0.5% PVI can attenuate congestion, edema and pain induced by pressure sores. Thus this study aimed to assess the effects of 0.5% PVI on acute skin wounds. Four full-thickness excisional wounds were generated on the dorsal skin ...

journal_title：Scientific reports

authors： Wang L,Qin W,Zhou Y,Chen B,Zhao X,Zhao H,Mi E,Mi E,Wang Q,Ning J

更新日期：2017-04-20 00:00:00

abstract：:The establishment of clinically relevant models for tumor metastasis and drug testing is a major challenge in cancer research. Here we report a physiologically relevant assay enabling quantitative analysis of metastatic capacity of tumor cells following implantation into the chorioallantoic membrane (CAM). Engraftment...

journal_title：Scientific reports

authors： Pawlikowska P,Tayoun T,Oulhen M,Faugeroux V,Rouffiac V,Aberlenc A,Pommier AL,Honore A,Marty V,Bawa O,Lacroix L,Scoazec JY,Chauchereau A,Laplace-Builhe C,Farace F

更新日期：2020-10-09 00:00:00

abstract：:Imaging and histopathological studies have demonstrated that structural changes of the retina affect subjects with Alzheimer's disease (AD) or mild cognitive impairment (MCI). The aim of this study was to quantitatively investigate the retinal vessels in these disorders, using dynamic vessel analyzer (DVA) and optical...

journal_title：Scientific reports

authors： Querques G,Borrelli E,Sacconi R,De Vitis L,Leocani L,Santangelo R,Magnani G,Comi G,Bandello F

更新日期：2019-01-11 00:00:00

abstract：:Experts have the superior cognitive capability of quickly understanding complex information in their domain; however, little is known about the neural processes underlying this ability. Here, using a board game named shogi (Japanese chess), we investigated the brain activity in expert players that was involved in thei...

journal_title：Scientific reports

authors： Nakatani H,Yamaguchi Y

更新日期：2014-07-31 00:00:00

abstract：:Ecosystem functions are regulated by compositional and functional traits of bacterial communities, shaped by stochastic and deterministic processes. Biogeographical studies have revealed microbial community taxonomy in a given ecosystem to change alongside varying environmental characteristics. Considering that stable...

journal_title：Scientific reports

authors： Booth JM,Fusi M,Marasco R,Mbobo T,Daffonchio D

更新日期：2019-03-06 00:00:00

abstract：:We report on an angle resolved photoemission (ARPES) study of bulk electron-doped perovskite iridate, (Sr(1-x)La(x))3Ir2O7. Fermi surface pockets are observed with a total electron count in keeping with that expected from La substitution. Depending on the energy and polarization of the incident photons, these pockets ...

journal_title：Scientific reports

authors： He J,Hafiz H,Mion TR,Hogan T,Dhital C,Chen X,Lin Q,Hashimoto M,Lu DH,Zhang Y,Markiewicz RS,Bansil A,Wilson SD,He RH

更新日期：2015-02-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Shirvani E,Paldurai A,Manoharan VK,Varghese BP,Samal SK

更新日期：2020-01-15 00:00:00

abstract：:Patterns of temperature fluctuations in nature affect numerous biological processes, yet, empirical studies often utilize constant temperature treatments. This can limit our understanding of how thermally sensitive species respond to ecologically relevant temperatures. Research on turtles with temperature-dependent se...

journal_title：Scientific reports

authors： Carter AW,Sadd BM,Tuberville TD,Paitz RT,Bowden RM

更新日期：2018-01-08 00:00:00

abstract：:Huntington disease (HD) is a late-onset genetic neurodegenerative disorder caused by expansion of cytosine-adenine-guanine (CAG) trinucleotide in the exon 1 of the gene encoding the polyglutamine (polyQ). It has been shown that protein degradation and lipid metabolism is altered in HD. In many neurodegenerative disord...

journal_title：Scientific reports

authors： Sameni S,Malacrida L,Tan Z,Digman MA

更新日期：2018-01-15 00:00:00

abstract：:Regulatory T cells (Tregs) expand in peripheral lymphoid organs and can produce immunosuppressive cytokines to support tumor growth. IL-10 abrogation efficiently induces Treg formation but dampens tumoral neuropilin-1 (Nrp-1) Treg signaling, which simultaneously augments Th1 and Th17 immunity. These effects are associ...

journal_title：Scientific reports

authors： Wang S,Gao X,Shen G,Wang W,Li J,Zhao J,Wei YQ,Edwards CK

更新日期：2016-04-14 00:00:00

abstract：:The amount of reduction in opioid doses and its effect on postoperative pain outcomes in chronic kidney disease (CKD) patients in the perioperative setting remains unclear. This study aimed to investigate differences in postoperative pain outcomes after major laparoscopic surgery between patients with CKD and those wi...

journal_title：Scientific reports

authors： Choi HR,Oh TK,Kim J,Jeon YT

更新日期：2019-03-08 00:00:00

abstract：:Salmonids show a high degree of phenotypic plasticity that can differ among genotypes, and this variation is one of the major factors contributing to uncertainty in extrapolating laboratory-based risk assessment data to nature. Many studies have examined the relative growth and survival of transgenic and non-transgeni...

journal_title：Scientific reports

authors： Vandersteen WE,Leggatt R,Sundström LF,Devlin RH

更新日期：2019-01-23 00:00:00