Abstract：
:Anxiety and depression are commonly found in patients with diabetes, but little is known about how the anxiety and depression symptoms of diabetes patients and the health-related quality of life (HRQoL) over time influence each other. Therefore, we conducted a survey among patients with diabetes (T1) and repeated the survey after 3 months (T2). Linear regression models and cross-lagged structural equation models were used to analyze the associations between anxiety and depression symptoms and HRQoL within and across time intervals. Correcting for baseline index and potential confounders, the HRQoL index at T2 reflected the change in anxiety/depression between T1 and T2 more than anxiety/depression at T1 (P < 0.05). Similarly, anxiety and depression at T2 reflected the change in the EQ-5D index over time more than the index at baseline (P < 0.05). Our longitudinal data fitted well in a cross-lagged model with bi-directional pathways of associations between anxiety and HRQoL, as well as depression and HRQoL, among adult patients with diabetes (x2/df = 1.102, P = 0.256; CFI = 1.000, RMSEA = 0.030). Our findings support early detection of anxiety and depression, as well as comprehensive efforts improving HRQoL for patients with diabetes.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Liu X,Haagsma J,Sijbrands E,Buijks H,Boogaard L,Mackenbach JP,Erasmus V,Polinder Sdoi
10.1038/s41598-020-57647-xsubject
Has Abstractpub_date
2020-05-20 00:00:00pages
8307issue
1issn
2045-2322pii
10.1038/s41598-020-57647-xjournal_volume
10pub_type
杂志文章abstract：:In cloud water, microorganisms are exposed to very strong stresses especially related to the presence of reactive oxygen species including H2O2 and radicals, which are the driving force of cloud chemistry. In order to understand how the bacterium Pseudomonas graminis isolated from cloud water respond to this oxidative...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49319-2
更新日期：2019-09-05 00:00:00
abstract：:Mesenchymal stem cells (MSC) are osteoblasts progenitors and a variety of studies suggest that they may play an important role for the health in the field of bone regeneration. Magnesium supplementation is gaining importance as adjuvant treatment to improve osteogenesis, although the mechanisms involving this process ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08379-y
更新日期：2017-08-10 00:00:00
abstract：:Competing endogenous RNA (ceRNA) have received wide attention because they are a novel way to regulate genes through sharing microRNAs (miRNAs) that are crucial for complex processes in many diseases. However, no systematic analysis of ceRNA mechanism in cardiovascular disease (CVD) is known. To gain insights into the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10547-z
更新日期：2017-08-31 00:00:00
abstract：ABSTARCT:Graphene has sparked extensive research interest for its excellent physical properties and its unique potential for application in absorption of electromagnetic waves. However, the processing of stable large-scale graphene and magnetic particles on a micrometer-thick conductive support is a formidable challeng...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02639-7
更新日期：2017-05-24 00:00:00
abstract：:Phenotypic heterogeneity is an important trait for the development and survival of many microorganisms including the yeast Cryptococcus spp., a deadly pathogen spread worldwide. Here, we have applied scanning electron microscopy (SEM) to define four Cryptococcus spp. capsule morphotypes, namely Regular, Spiky, Bald, a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59276-w
更新日期：2020-02-11 00:00:00
abstract：:We tested the hypothesis that modulation of neurocomputational inputs to value-based decision-making affects the rationality of economic choices. The brain's right temporoparietal junction (rTPJ) has been functionally associated with both social behavior and with domain-general information processing and attention. To...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76956-9
更新日期：2020-11-20 00:00:00
abstract：:Growth in salmon aquaculture over the past two decades has raised concerns regarding the potential impacts of the industry on neighboring ecosystems and wild fish productivity. Despite limited evidence, sea lice have been identified as a major cause for the decline in some wild Pacific salmon populations on the west c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22458-8
更新日期：2018-03-05 00:00:00
abstract：:Oxidative stress due to hypobaric hypoxia at extreme altitudes causes severe neuronal damage and irreversible cognitive loss. Owing to contraindications of current drug therapies, the aim of the study was to investigate memory enhancing potential of aqueous extract of Ganoderma lucidum (GLAQ) and underlying neuroprote...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65812-5
更新日期：2020-06-02 00:00:00
abstract：:Inversely tapered silicon photonic resonators on silicon substrates were shown to host multiple high-Q whispering gallery modes and constitute versatile building blocks for CMOS compatible solid state lighting, optical sensing and modulator devices. So far, numerical analyses by the finite difference time domain metho...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45034-0
更新日期：2019-06-21 00:00:00
abstract：:Maternal obesity in pregnancy increases the risk of adverse long-term health outcomes in both mother and offspring. A population-based cohort of prospectively collected routine antenatal healthcare data collected between January 2003 and September 2017 at University Hospital Southampton, UK was utilised to investigate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45595-0
更新日期：2019-06-24 00:00:00
abstract：:Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35836-z
更新日期：2018-11-27 00:00:00
abstract：:Impaired wound healing is an immense medical challenge, and while autologous skin grafting remains the "gold-standard" therapeutic option for repairing wounds that cannot be closed by primary or secondary intention, it is limited by substantial donor site morbidity. We previously developed the alternative approach of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81179-7
更新日期：2021-01-18 00:00:00
abstract：:Local and global changes associated with anthropogenic activities are impacting marine and terrestrial ecosystems. Macroalgae, especially habitat-forming species like kelp, play critical roles in temperate coastal ecosystems. However, their abundance and distribution patterns have been negatively affected by warming i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60104-4
更新日期：2020-02-21 00:00:00
abstract：:Plant extracts, or phytonutrients, are used in traditional medicine practices as supplements to enhance the immune system and gain resistance to various infectious diseases and are used in animal production as health promoting feed additives. To date, there are no studies that have assessed their mechanism of action a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09253
更新日期：2015-03-19 00:00:00
abstract：:Cyanobacteria are ubiquitous organisms with a relevant contribution to primary production in all range of habitats. Cyanobacteria are well known for their part in worldwide occurrence of aquatic blooms while producing a myriad of natural compounds, some with toxic potential, but others of high economical impact, as ge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64774-y
更新日期：2020-05-26 00:00:00
abstract：:Amblyopia is a common visual disorder that is treatable in childhood. However, therapies have limited efficacy in adult patients with amblyopia. Fluoxetine can reinstate early-life critical period-like neuronal plasticity and has been used to recover functional vision in adult rats with amblyopia. We conducted a Phase...
journal_title：Scientific reports
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/s41598-018-31169-z
更新日期：2018-08-27 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep44888. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/srep46881
更新日期：2017-08-29 00:00:00
abstract：:Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson's disease and Huntington's disease. Antipsychotics are drugs that interact primarily with the dopamine ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78446-4
更新日期：2020-12-09 00:00:00
abstract：:Most enzymes that act on carbohydrates include non-catalytic carbohydrate-binding modules (CBMs) that recognize and target carbohydrates. CBMs bring their appended catalytic modules into close proximity with the target substrate and increase the hydrolytic rate of enzymes acting on insoluble substrates. We previously ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19392
更新日期：2016-01-14 00:00:00
abstract：:Previous studies have investigated the use of mesenchymal stem cells (MSCs) to treat damaged kidneys. However, the effect of adipose-derived MSCs (ASCs) on vascular calcification in chronic kidney disease (CKD) is still poorly understood. In the present study, we explored the potential of ASCs for the treatment of CKD...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14492-9
更新日期：2017-10-25 00:00:00
abstract：:Nonalcoholic fibrosing steatohepatitis is a uniform process throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been suggested to modulate cellular processes in liver diseases. However, the functional role of miRNAs in nonalcoholic fibrosing steatohepatitis is largely unclear. In this study, w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16163
更新日期：2015-11-05 00:00:00
abstract：:Acclimation and adaptation, which are key to species survival in a changing climate, can be observed in terms of membrane lipid composition. Remodelling membrane lipids, via homeoviscous adaptation (HVA), counteracts membrane dysfunction due to temperature in poikilotherms. In order to assess the potential for acclima...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35669
更新日期：2016-10-20 00:00:00
abstract：:Horizontal gene transfer (HGT) was attributed as a major driving force for the innovation and evolution of prokaryotic genomes. Previously, multiple research endeavors were undertaken to decipher HGT in different bacterial lineages. The genus Mycobacterium houses some of the most deadly human pathogens; however, the i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33261-w
更新日期：2018-10-04 00:00:00
abstract：:Type-II Diabetes Mellitus (T2DM) is one of the fastest growing public health issues of modern times, consuming 12% of worldwide health budgets and affecting an estimated 400 million people. A key pathological trait associated with this disease is the failure of normal glucose-stimulated insulin secretion (GSIS) from p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39681-6
更新日期：2019-02-27 00:00:00
abstract：:Plants perceive and respond to volatile signals in their environment. Herbivore-infested plants release volatile organic compounds (VOCs) which can initiate systemic defense reactions within the plant and contribute to plant-plant communication. Here, for Ipomoea batatas (sweet potato) leaves we show that among variou...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53946-0
更新日期：2019-11-22 00:00:00
abstract：:Quaternized polyacrylic polymer has many applications in water treatment because of its ion exchange effects, but its further industrial applications are largely restricted because of its poor mechanical strength. In this work, a magnetic anion exchange resin with a polyacrylic matrix (MAP) was prepared by incorporati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62153-1
更新日期：2020-03-23 00:00:00
abstract：:We analysed the imaging findings of macular telangiectasia (MacTel) type 2 in Korea using spectral domain optical coherence tomography (SD-OCT) and investigated their relationship with visual acuity and clinical stages. A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73803-9
更新日期：2020-10-06 00:00:00
abstract：:Studies on prevalence and significance of alternative polyadenylation (APA) in plants have been so far limited mostly to the model plants. Here, a genome-wide analysis of APA was carried out in different tissue types in the non-model forage legume red clover (Trifolium pratense L). A profile of poly(A) sites in differ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29699-7
更新日期：2018-07-27 00:00:00
abstract：:Bast fibres are long extraxylary cells which mechanically support the phloem and they are divided into xylan- and gelatinous-type, depending on the composition of their secondary cell walls. The former, typical of jute/kenaf bast fibres, are characterized by the presence of xylan and a high degree of lignification, wh...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05200-8
更新日期：2017-07-10 00:00:00
abstract：:The pathophysiology of stress cardiomyopathy (SCM), also known as takotsubo syndrome, is poorly understood. SCM usually occurs sporadically, often in association with a stressful event, but clusters of cases are reported after major natural disasters. There is some evidence that this is a familial condition. We have e...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25827-5
更新日期：2018-05-15 00:00:00
