Reformation of the Electron Internal Transport Barrier with the Appearance of a Magnetic Island.

abstract：:Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that controls the cellular response to oxidative stress and possesses DNA-repair functions. It has important roles in the progression and outcomes of various diseases; however, its function and therapeutic prospects with respect to kidney injury ...

journal_title：Scientific reports

authors： Maruyama K,Nakagawa N,Aonuma T,Saito Y,Hayasaka T,Kano K,Horiuchi K,Takehara N,Kawabe JI,Hasebe N

更新日期：2019-05-24 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models. Inherent challenges, however, are the pluripotency of IVIG and its xenogeneicity in animals. IVIG can alter the viability of human neutrophils v...

journal_title：Scientific reports

authors： Schneider C,Wicki S,Graeter S,Timcheva TM,Keller CW,Quast I,Leontyev D,Djoumerska-Alexieva IK,Käsermann F,Jakob SM,Dimitrova PA,Branch DR,Cummings RD,Lünemann JD,Kaufmann T,Simon HU,von Gunten S

更新日期：2017-05-02 00:00:00

abstract：:Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S. meningococcal isolates (N = 201) from 15 epidemiologically defined outbreaks (2009-2015) along with temporally and geographic...

journal_title：Scientific reports

authors： Whaley MJ,Joseph SJ,Retchless AC,Kretz CB,Blain A,Hu F,Chang HY,Mbaeyi SA,MacNeil JR,Read TD,Wang X

更新日期：2018-10-25 00:00:00

abstract：:Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shikimate kinase I and...

journal_title：Scientific reports

authors： Gu P,Su T,Wang Q,Liang Q,Qi Q

更新日期：2016-07-13 00:00:00

abstract：:The purpose of this study is to investigate whether implementing a myofascial release (MFR) protocol designed to restore the myofascial properties of the diaphragm has any effect on the symptoms, quality of life, and consumption of proton pump inhibitors (PPI) drugs by patients with non-erosive gastroesophageal reflux...

journal_title：Scientific reports

authors： Martínez-Hurtado I,Arguisuelas MD,Almela-Notari P,Cortés X,Barrasa-Shaw A,Campos-González JC,Lisón JF

更新日期：2019-05-13 00:00:00

abstract：:SHH Medulloblastoma (SHH-MB) is a pediatric brain tumor characterized by an inappropriate activation of the developmental Hedgehog (Hh) signaling. SHH-MB patients treated with the FDA-approved vismodegib, an Hh inhibitor that targets the transmembrane activator Smoothened (Smo), have shown the rapid development of dru...

journal_title：Scientific reports

authors： Coni S,Mancuso AB,Di Magno L,Sdruscia G,Manni S,Serrao SM,Rotili D,Spiombi E,Bufalieri F,Petroni M,Kusio-Kobialka M,De Smaele E,Ferretti E,Capalbo C,Mai A,Niewiadomski P,Screpanti I,Di Marcotullio L,Canettieri G

更新日期：2017-03-09 00:00:00

abstract：:Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been shown to regulate human neutrophil function, potentiate systemic inflammation. Nevertheless, EMR2 could also suppr...

journal_title：Scientific reports

authors： Huang CH,Jeng WJ,Ho YP,Teng W,Hsieh YC,Chen WT,Chen YC,Lin HH,Sheen IS,Lin CY

更新日期：2016-12-01 00:00:00

abstract：:We present two transmission-mode dielectric Fresnel-Zone Plate Lens (FZPL) antennas for use within the V-band spectrum. The proposed FZPs are realized via pure plastic material using two different additive manufacturing processes. The proposed FZP lenses are designed with half (λ/2) and quarter (λ/4) phase correction ...

journal_title：Scientific reports

authors： Pourahmadazar J,Denidni TA

更新日期：2018-03-28 00:00:00

abstract：:The high neutron detection efficiency, good gamma-ray discrimination and non-toxicity of 3He made of proportional counters filled with this gas the obvious choice for neutron detection, particularly in radiation portal monitors (RPM), used to control the illicit transport of nuclear material, of which neutron detector...

journal_title：Scientific reports

authors： Amaro FD,Monteiro CM,Dos Santos JM,Antognini A

更新日期：2017-02-09 00:00:00

abstract：:The study of animal vocal signals can either focus on the properties of distinct vocal elements or address the signal as a whole. Although some attention has been given to the continuous progression patterns of bird songs, such patterns in mammalian vocalisations have been largely overlooked. We examined temporal chan...

journal_title：Scientific reports

authors： Demartsev V,Ilany A,Kershenbaum A,Geva Y,Margalit O,Schnitzer I,Barocas A,Bar-Ziv E,Koren L,Geffen E

更新日期：2017-06-05 00:00:00

abstract：:Many drugs commonly prescribed during pregnancy lack a fetal safety recommendation - called FDA 'category C' drugs. This study aims to classify these drugs into harmful and safe categories using knowledge gained from chemoinformatics (i.e., pharmacological similarity with drugs of known fetal effect) and empirical dat...

journal_title：Scientific reports

authors： Boland MR,Polubriaginof F,Tatonetti NP

更新日期：2017-10-09 00:00:00

abstract：:In the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression...

journal_title：Scientific reports

authors： Reclusa P,Verstraelen P,Taverna S,Gunasekaran M,Pucci M,Pintelon I,Claes N,de Miguel-Pérez D,Alessandro R,Bals S,Kaushal S,Rolfo C

更新日期：2020-04-16 00:00:00

abstract：:Extreme weather events (e.g., cyclones, floods, droughts) are capable of changing ecosystems and altering how animals obtain resources. Understanding the behavioural responses of animals being impacted by these natural events can help initiate and ameliorate conservation or management programs. This study investigated...

journal_title：Scientific reports

authors： Matley JK,Eanes S,Nemeth RS,Jobsis PD

更新日期：2019-10-03 00:00:00

abstract：:Nesfatin-1, a satiety molecule processed from nucleobindin2 (NUCB2), is implicated in visceral hypersensitivity in rats and colocalized with 5-hydroxytryptamine (5-HT) in the dorsal raphe nucleus (DRN). Maternal separation (MS) in rats contributes to visceral hypersensitivity via elevated expression of 5-HT in the DRN...

journal_title：Scientific reports

authors： Zhang HA,Sang N,Ge X,Huang Q,Li XL,Sha J

更新日期：2018-06-19 00:00:00

abstract：:Potato (Solanum tuberosum L.) is the fourth most important crop worldwide. Potato virus A (PVA) is one of the most harmful viruses infecting potatoes. However, the molecular mechanisms governing the responses to PVA infection in potato at the transcriptional and post-transcriptional levels are not well understood. In ...

journal_title：Scientific reports

authors： Li Y,Hu X,Chen J,Wang W,Xiong X,He C

更新日期：2017-12-05 00:00:00

abstract：:Dissimilatory nitrate reduction to ammonium (DNRA) is an important nitrate reduction process in estuarine sediments. This study reports the first investigation of DNRA in the Yellow River Estuary located in Eastern Shandong, China. Saltwater intrusion could affect the physicochemical characteristics and change the mic...

journal_title：Scientific reports

authors： Bu C,Wang Y,Ge C,Ahmad HA,Gao B,Ni SQ

更新日期：2017-07-28 00:00:00

abstract：:The irritant receptor TRPA1 was suggested to mediate analgesic, antipyretic but also pro-inflammatory effects of the non-opioid analgesic acetaminophen, presumably due to channel activation by the reactive metabolites parabenzoquinone (pBQ) and N-acetyl-parabenzoquinonimine (NAPQI). Here we explored the effects of the...

journal_title：Scientific reports

authors： Eberhardt MJ,Schillers F,Eberhardt EM,Risser L,de la Roche J,Herzog C,Echtermeyer F,Leffler A

更新日期：2017-10-06 00:00:00

abstract：:MicroRNAs are a class of small noncoding RNAs that regulate gene expression post-transcriptionally either by inhibiting protein translation or by causing the degradation of target mRNAs. Current evidence indicates that miR-33b is involved in the regulation of lipid metabolism, cholesterol homeostasis, glucose metaboli...

journal_title：Scientific reports

authors： Lin Y,Liu AY,Fan C,Zheng H,Li Y,Zhang C,Wu S,Yu D,Huang Z,Liu F,Luo Q,Yang CJ,Ouyang G

更新日期：2015-04-28 00:00:00

abstract：:Several studies have shown that the 'poor' sperm DNA quality appears to be an important factor affecting male reproductive ability. In the case of sperm cells from males with the correct somatic karyotype but with deficient spermatogenesis, resulting in a high degree of sperm DNA fragmentation, we observed changes in ...

journal_title：Scientific reports

authors： Wiland E,Fraczek M,Olszewska M,Kurpisz M

更新日期：2016-08-25 00:00:00

abstract：:Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery. As human pluripotent stem cell-derived cardiomyocytes remain functionally fetal-type, close monitoring of electrophysiological maturation is critical for their furthe...

journal_title：Scientific reports

authors： Zhu H,Scharnhorst KS,Stieg AZ,Gimzewski JK,Minami I,Nakatsuji N,Nakano H,Nakano A

更新日期：2017-03-07 00:00:00

abstract：:By using a half soap bubble heated from below, we obtain large isolated single vortices whose properties as well as their intensity are measured under different conditions. By studying the effects of rotation of the bubble on the vortex properties, we found that rotation favors vortices near the pole. Rotation also in...

journal_title：Scientific reports

authors： Meuel T,Xiong YL,Fischer P,Bruneau CH,Bessafi M,Kellay H

更新日期：2013-12-13 00:00:00

abstract：:Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse model. Expression analyses revea...

journal_title：Scientific reports

authors： Milora KA,Uppalapati SR,Sanmiguel JC,Zou W,Jensen LE

更新日期：2017-07-19 00:00:00

abstract：:The American mink (Neovison vison) is a semiaquatic species of mustelid native to North America. It's an important animal for the fur industry. Many efforts have been made to locate genes influencing fur quality and color, but this search has been impeded by the lack of a reference genome. Here we present the first dr...

journal_title：Scientific reports

authors： Cai Z,Petersen B,Sahana G,Madsen LB,Larsen K,Thomsen B,Bendixen C,Lund MS,Guldbrandtsen B,Panitz F

更新日期：2017-11-06 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Lee DB,Kim JM,Seok JH,Lee JH,Jo JD,Mun JY,Conrad C,Coe J,Nelson G,Hogue B,White TA,Zatsepin N,Weierstall U,Barty A,Chapman H,Fromme P,Spence J,Chung MS,Oh CH,Kim KH

更新日期：2018-04-17 00:00:00

abstract：:Silver nanorod arrays prepared by oblique angle deposition (AgOADs) represent versatile, simple and inexpensive substrates for high sensitivity surface enhanced Raman scattering (SERS) applications. Their anisotropic nature suggests that their optical responses such as the SERS signal, the depolarization ratio, reflec...

journal_title：Scientific reports

authors： Šubr M,Petr M,Kylián O,Štěpánek J,Veis M,Procházka M

更新日期：2017-06-27 00:00:00

abstract：:This study reports atomic-scale characterization of structural defects in Yb2Ti2O7, a pyrochlore oxide whose subtle magnetic interactions is prone to small perturbations. Due to discrepancies in the reported magnetic ground states, it has become a pressing issue to determine the nature of defects in this system. In th...

journal_title：Scientific reports

authors： Shafieizadeh Z,Xin Y,Koohpayeh SM,Huang Q,Zhou H

更新日期：2018-11-21 00:00:00

abstract：:Modern society characterized by a 24/7 lifestyle leads to misalignment between environmental cycles and endogenous circadian rhythms. Persisting circadian misalignment leads to deleterious effects on health and healthspan. However, the underlying mechanism remains not fully understood. Here, we subjected adult, wild-t...

journal_title：Scientific reports

authors： Inokawa H,Umemura Y,Shimba A,Kawakami E,Koike N,Tsuchiya Y,Ohashi M,Minami Y,Cui G,Asahi T,Ono R,Sasawaki Y,Konishi E,Yoo SH,Chen Z,Teramukai S,Ikuta K,Yagita K

更新日期：2020-02-13 00:00:00

abstract：:Age-specific genetic and antigenic variations of influenza viruses have not been documented in tropical and subtropical regions. We implemented a systematic surveillance program in two tertiary hospitals in Hong Kong Island, to collect 112 A(H1N1)pdm09 and 254 A(H3N2) positive specimens from 2013 to 2014. Of these, 56...

journal_title：Scientific reports

authors： Cao P,Wong CM,Chan KH,Wang X,Chan KP,Peiris JS,Poon LL,Yang L

更新日期：2016-07-25 00:00:00

abstract：:For people with synaesthesia ordinary stimuli such as digits or letters induce concurrent experiences such as colours. Synaesthesia is associated with a memory advantage and the aim of this study was to investigate whether this advantage persists across time. We tested recognition memory of four different types of syn...

journal_title：Scientific reports

authors： Lunke K,Meier B

更新日期：2020-02-26 00:00:00

abstract：:We investigate, for the first time, navigation on networks with a Lévy walk strategy such that the step probability scales as pij ~ dij(-α), where dij is the Manhattan distance between nodes i and j, and α is the transport exponent. We find that the optimal transport exponent α(opt) of such a diffusion process is dete...

journal_title：Scientific reports

authors： Weng T,Small M,Zhang J,Hui P

更新日期：2015-11-25 00:00:00