Abstract：
:The voluntary control of movement is often tested by using the countermanding, or stop-signal task that sporadically requires the suppression of a movement in response to an incoming stop-signal. Neurophysiological recordings in monkeys engaged in the countermanding task have shown that dorsal premotor cortex (PMd) is implicated in movement control. An open question is whether and how the perceptual demands inherent the stop-signal affects inhibitory performance and their underlying neuronal correlates. To this aim we recorded multi-unit activity (MUA) from the PMd of two male monkeys performing a countermanding task in which the salience of the stop-signals was modulated. Consistently to what has been observed in humans, we found that less salient stimuli worsened the inhibitory performance. At the neuronal level, these behavioral results were subtended by the following modulations: when the stop-signal was not noticeable compared to the salient condition the preparatory neuronal activity in PMd started to be affected later and with a less sharp dynamic. This neuronal pattern is probably the consequence of a less efficient inhibitory command useful to interrupt the neural dynamic that supports movement generation in PMd.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Pani P,Giarrocco F,Giamundo M,Montanari R,Brunamonti E,Ferraina Sdoi
10.1038/s41598-018-32669-8subject
Has Abstractpub_date
2018-09-24 00:00:00pages
14265issue
1issn
2045-2322pii
10.1038/s41598-018-32669-8journal_volume
8pub_type
杂志文章abstract：:Time-series data from multicomponent systems capture the dynamics of the ongoing processes and reflect the interactions between the components. The progression of processes in such systems usually involves check-points and events at which the relationships between the components are altered in response to stimuli. Det...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08937
更新日期：2015-03-11 00:00:00
abstract：:The microbiota colonized on human body is renowned as "a forgotten organ" due to its big impacts on human health and disease. Recently, microbiome studies have identified a large number of microbes differentially regulated in a variety of conditions, such as disease and diet. However, methods for discovering biologica...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40200
更新日期：2017-01-10 00:00:00
abstract：:Hypoxia inducible factor-1α (HIF-1α) pathway is associated with many vascular diseases, including atherosclerosis, arterial aneurysms, pulmonary hypertension and chronic venous diseases. Significant HIF-1α expression could be found at the rupture edge at human abdominal aortic aneurysm (AAA) tissues. While our initial...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28612
更新日期：2016-07-01 00:00:00
abstract：:Photonic structure designs based on optimization algorithms provide superior properties compared to those using intuition-based approaches. In the present study, we numerically and experimentally demonstrate subwavelength focusing of light using wavelength scale absorption-free dielectric scattering objects embedded i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30871
更新日期：2016-08-01 00:00:00
abstract：:To compare the different features of necrotizing pneumonia (NP) and non-NP (NNP) caused by Mycoplasma pneumoniae pneumonia (MPP) with large pulmonary lesions, and explore the predictor for NP to differentiate from MPP. A retrospective study of MPP patients with large pulmonary lesions hospitalized from January 2008 to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76083-5
更新日期：2020-11-04 00:00:00
abstract：:In the past few years, the meteoric development of hybrid organic-inorganic perovskite solar cells (PSC) astonished the community. The efficiency has already reached the level needed for commercialization; however, the instability hinders its deployment on the market. Here, we report a mechanism to chemically stabiliz...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30305
更新日期：2016-07-26 00:00:00
abstract：:Clostridial neurotoxins (CNTs), which include botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT), are the most potent toxins known to science and are the causative agents of botulism and tetanus, respectively. The evolutionary origins of CNTs and their relationships to other proteins remains an intriguing que...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37647-8
更新日期：2019-02-07 00:00:00
abstract：:Autoimmune diseases mediated by a type of white blood cell-T lymphocytes-are currently treated using mainly broad-spectrum immunosuppressants that can lead to adverse side effects. Antioxidants represent an alternative approach for therapy of autoimmune disorders; however, dietary antioxidants are insufficient to play...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33808
更新日期：2016-09-22 00:00:00
abstract：:Human populations worldwide are increasingly confronted with infectious diseases and antimicrobial resistance spreading faster and appearing more frequently. Knowledge regarding their occurrence and worldwide transmission is important to control outbreaks and prevent epidemics. Here, we performed shotgun sequencing of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11444
更新日期：2015-07-10 00:00:00
abstract：:The formation of Pb, Zn, and Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from the 15th century to the present. Through transport phenomena not yet understood, free fatty acids in the oil binding medium migrate through the paint and react with pigments containing heavy m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11525-1
更新日期：2017-09-14 00:00:00
abstract：:We identify a new instability in electrostatic actuators dubbed quasi-static pull-in. We report experimental evidence of the instability and study its characteristics in two types of micro actuators operating in ambient air. We found that the underlying mechanism is a fast-slow dynamic interaction between slowly-varyi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61534-w
更新日期：2020-03-19 00:00:00
abstract：:The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated. However, there is little or no information in the literature on the problems of reproducibility of data originating from experiments us...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19103
更新日期：2016-01-11 00:00:00
abstract：:The effect of annealing both in the oxygen atmosphere and at room temperatures on physical properties such as the pseudogap (Δ*(T)) and excess conductivity (σ'(T)) of untwined YBa2Cu3O7-δ (YBCO) single crystal with a small deviation from oxygen stoichiometry is studied. It was revealed that as the charge carrier densi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45286-w
更新日期：2019-06-25 00:00:00
abstract：:Starting from the dataset of the publication corpus of the APS during the period 1955-2009, we reconstruct the individual researchers trajectories, namely the list of the consecutive affiliations for each scholar. Crossing this information with different geographic datasets we embed these trajectories in a spatial fra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04860
更新日期：2014-05-07 00:00:00
abstract：:Keyboards and smartphones allow users to express their thoughts freely via manual control. Hands-free communication can be realized with brain-computer interfaces (BCIs) based on code-modulated visual evoked potentials (c-VEPs). Various variations of such spellers have been developed: Low-target systems, multi-target ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74143-4
更新日期：2020-10-13 00:00:00
abstract：:A top-down scalable method to produce flexible water and blood repellent tubes is introduced. The method is based on replication of overhanging nanostructures from an aluminum tube template to polydimethylsiloxane (PDMS) via atomic layer deposition (ALD) assisted sacrificial etching. The nanostructured PDMS/titania tu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16369-3
更新日期：2017-11-22 00:00:00
abstract：:Arctic and alpine environments present extreme, but different, challenges to survival. We therefore studied the ecological adaptation of the arctic-alpine fritillary Boloria napaea in northern Sweden and compared these results with the eastern Alps. Using mark-release-recapture, we analysed phenology, mobility, activi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40508-7
更新日期：2019-03-07 00:00:00
abstract：:Cardiac resynchronization therapy (CRT) threw lights on heart failure treatment, however, parts of patients showed nonresponse to CRT. Unfortunately, it lacks effective parameters to predict CRT non-response. In present study, we try to seek effective electro-echocardiographic predictors on CRT non-response. This is a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44009
更新日期：2017-03-10 00:00:00
abstract：:Practical alternatives to gold-standard measures of circadian timing in shift workers are needed. We assessed the feasibility of applying a limit-cycle oscillator model of the human circadian pacemaker to estimate circadian phase in 25 nursing and medical staff in a field setting during a transition from day/evening s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47290-6
更新日期：2019-07-30 00:00:00
abstract：:Gallbladder cancer (GBC) is a highly malignant tumor with poorly understood etiology. An insight into phenotypic features of this malignancy may add to the knowledge of its carcinogenesis and pave the way to new therapeutic approaches. We assessed the expression of female sex hormone receptors (ERα, ERβ, PR), connecti...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58777-y
更新日期：2020-02-05 00:00:00
abstract：:Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but the estimation of the secondary structure content fails when light scattering leads to spectral distortion. If peptide-induced liposome self-association occurs, subtracting contro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39450
更新日期：2016-12-22 00:00:00
abstract：:Amazonian wildfires in 2019 have raised awareness about rainforest burning due to increased emissions of particulate matter and carbon. In the context of these emissions, by-products of lignin thermal degradation (i.e. methoxyphenols) are often neglected. Methoxyphenols entering the atmosphere may form intermediates w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81789-1
更新日期：2021-01-28 00:00:00
abstract：:Formamidinium lead iodide (CH(NH2)2PbI3, FAPI) thin films have been deposited on glass substrates at 150 °C using ambient pressure aerosol assisted chemical vapour deposition (AACVD). The films have been analysed by a range of techniques including powder X-ray diffraction (pXRD), scanning electron microscopy (SEM), en...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79291-1
更新日期：2020-12-17 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep44640. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/srep46872
更新日期：2017-06-30 00:00:00
abstract：:Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes to T-cell differentiation and function. Adenosine concentrations are furthermore influenced by adenosine deaminase binding protein CD26. Because aberrant T-cell phenotypes had been reported in anti-neutrophil cytoplasmic auto-ant...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12011-4
更新日期：2017-09-15 00:00:00
abstract：:In this work, we introduce a novel and facile method of exfoliating large-area, single-layer graphene oxide using a shearing stress. The shearing stress reactor consists of two concentric cylinders, where the inner cylinder rotates at controlled speed while the outer cylinder is kept stationary. We found that the form...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16649-y
更新日期：2017-11-27 00:00:00
abstract：:There has been a significant increase in autism spectrum disorder (ASD) in the last decades that cannot be exclusively attributed to better diagnosis and an increase in the communication of new cases. Patients with ASD often show dysregulation of proteins associated with synaptic plasticity, notably brain-derived neur...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74239-x
更新日期：2020-10-15 00:00:00
abstract：:Recent advances in microfluidic cell cultures enable the construction of in vitro human skin models that can be used for drug toxicity testing, disease study. However, current in vitro skin model have limitations to emulate real human skin due to the simplicity of model. In this paper, we describe the development of '...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37471
更新日期：2016-11-21 00:00:00
abstract：:This study investigated the effects of a contoured, prefabricated foot orthosis and a flat insole on plantar pressure and tibial acceleration while walking in defence boots. Twenty-eight adults walked along an 8-metre walkway in a: (i) defence boot (control condition), (ii) defence boot with a flat insole, and (iii) d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35830-5
更新日期：2019-02-08 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-57833-x
更新日期：2020-01-15 00:00:00
