Non-destructive elemental analysis of a carbonaceous chondrite with direct current Muon beam at MuSIC.

abstract：:PP2A is a master controller of multiple inflammatory signaling pathways. It is a target in asthma; however the molecular mechanisms by which PP2A controls inflammation warrant further investigation. In A549 lung epithelial cells in vitro we show that inhibition of basal PP2A activity by okadaic acid (OA) releases rest...

journal_title：Scientific reports

authors： Rahman MM,Rumzhum NN,Morris JC,Clark AR,Verrills NM,Ammit AJ

更新日期：2015-05-18 00:00:00

abstract：:Gait speed in laboratory settings (in-laboratory gait speed) is one of the important indicators associated with the decline in functional abilities in older adulthood. Recently, it has become possible to measure gait speed during daily living (daily gait speed) using accelerometers. However, the relationship between t...

journal_title：Scientific reports

authors： Takayanagi N,Sudo M,Yamashiro Y,Lee S,Kobayashi Y,Niki Y,Shimada H

更新日期：2019-03-05 00:00:00

abstract：:We demonstrate application of the method of higher-order operators to nonlinear standard optomechanics. It is shown that a symmetry breaking in frequency shifts exists, corresponding to inequivalency of red and blue side-bands. This arises from nonlinear higher-order processes leading to inequal detunings. Similarly, ...

journal_title：Scientific reports

authors： Khorasani S

更新日期：2018-08-01 00:00:00

abstract：:Dengue virus infection is a global threat for which no specific treatment has not been established. Previous reports suggested chrysin and flavanone derivatives were potential flaviviral inhibitors. Here, we reported two halogenated chrysins, abbreviated FV13 and FV14, were highly potent against DENV1-4 and ZIKV infec...

journal_title：Scientific reports

authors： Suroengrit A,Yuttithamnon W,Srivarangkul P,Pankaew S,Kingkaew K,Chavasiri W,Boonyasuppayakorn S

更新日期：2017-10-20 00:00:00

abstract：:The Great East Japan Earthquake on 11 March 2011, caused the release of radioactive materials from the Fukushima Daiichi Nuclear Power Plant (FDNPP), contaminating eastern Japan, particularly in part of Fukushima Prefecture. In 2012 and 2014, the radiocaesium concentration in brown rice did not exceed regulatory level...

journal_title：Scientific reports

authors： Matsunami H,Murakami T,Fujiwara H,Shinano T

更新日期：2016-02-04 00:00:00

abstract：:Neuroscience findings have recently received critique on the lack of replications. To examine the reproducibility of brain indices of speech sound discrimination and their role in dyslexia, a specific reading difficulty, brain event-related potentials using EEG were measured using the same cross-linguistic passive odd...

journal_title：Scientific reports

authors： Leppänen PHT,Tóth D,Honbolygó F,Lohvansuu K,Hämäläinen JA,NEURODYS WP7 group.,Demonet JF,Schulte-Körne G,Csépe V

更新日期：2019-06-11 00:00:00

abstract：:Personalized medicine is a promising tool not only for prevention, screening and development of more efficient treatment strategies, but also for diminishing the side effects caused by current therapies. Deciphering gene regulation pathways provides a reliable prognostic analysis to elucidate the origin of grave disea...

journal_title：Scientific reports

authors： Huertas CS,Domínguez-Zotes S,Lechuga LM

更新日期：2017-01-25 00:00:00

abstract：:Arbuscular mycorrhizal fungi (AMF) can be beneficial for improving restoration of radioactive-cesium (137Cs)-contaminated soils through soil remediation. However, there has been no information on species diversity and the composition of AMF communities in 137Cs-contaminated soil after the Fukushima-Daiichi Nuclear Pow...

journal_title：Scientific reports

authors： Higo M,Kang DJ,Isobe K

更新日期：2019-06-03 00:00:00

abstract：:Low pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour site, while sparing healthy tissues. To this end, pH-sensitive, hollow ZnO-nanocarriers loaded with paclitaxel were sy...

journal_title：Scientific reports

authors： Puvvada N,Rajput S,Kumar BNP,Sarkar S,Konar S,Brunt KR,Rao RR,Mazumdar A,Das SK,Basu R,Fisher PB,Mandal M,Pathak A

更新日期：2015-07-06 00:00:00

abstract：:Worldwide biodiversity assessments have mainly focused on species richness but little is known about the diversity of species roles, i.e. functional diversity, while this is a key facet to understanding the consequences of global changes on the ecosystem services to human societies. Here, we report the world pattern o...

journal_title：Scientific reports

authors： Toussaint A,Charpin N,Brosse S,Villéger S

更新日期：2016-03-16 00:00:00

abstract：:This paper presents a study of noise in room-temperature THz radiometers that use THz-to-optical upconversion followed by optical detection of thermal radiation. Despite some undesired upconverted thermal noise, no noise is intrinsically introduced by efficient electro-optic modulation via a sum-frequency-generation p...

journal_title：Scientific reports

authors： Santamaría-Botello G,Popovic Z,Abdalmalak KA,Segovia-Vargas D,Brown ER,García Muñoz LE

更新日期：2020-06-10 00:00:00

abstract：:Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for comparisons of clinical parameters in...

journal_title：Scientific reports

authors： Joshita S,Umemura T,Usami Y,Yamashita Y,Norman GL,Sugiura A,Yamazaki T,Fujimori N,Kimura T,Matsumoto A,Igarashi K,Yoshizawa K,Ota M,Tanaka E

更新日期：2018-05-25 00:00:00

abstract：:In a standard semiconductor laser, electrons and holes recombine via stimulated emission to emit coherent light, in a process that is far from thermal equilibrium. Exciton-polariton condensates-sharing the same basic device structure as a semiconductor laser, consisting of quantum wells coupled to a microcavity-have b...

journal_title：Scientific reports

authors： Horikiri T,Yamaguchi M,Kamide K,Matsuo Y,Byrnes T,Ishida N,Löffler A,Höfling S,Shikano Y,Ogawa T,Forchel A,Yamamoto Y

更新日期：2016-05-19 00:00:00

abstract：:The reprogramming of differentiated cells into induced pluripotent stem cells (iPSCs) can be achieved by ectopic expression of defined transcription factors (Oct3/4, Sox2, Klf4 and c-Myc). However, to date, some iPSCs have been generated using viral vectors; thus, unexpected insertional mutagenesis in the target cells...

journal_title：Scientific reports

authors： Dai P,Harada Y,Miyachi H,Tanaka H,Kitano S,Adachi T,Suzuki T,Hino H,Takamatsu T

更新日期：2014-12-04 00:00:00

abstract：:A novel polyphenolic natural product, galewone, with undescribed carbon skeleton, was isolated as a racemate from the culture of Daldinia eschscholzii IFB-TL01, a fungus obtained from the mantis (Tenodera aridifolia) gut. The galewone structure was elucidated by a combination of MS and NMR spectra, and substantiated b...

journal_title：Scientific reports

authors： Zhang AH,Jiang N,Wang XQ,Tan RX

更新日期：2019-10-04 00:00:00

abstract：:Approximately 300,000 men around the globe self-identify as Ashkenazi Levites, of whom two thirds were previously shown to descend from a single male. The paucity of whole Y-chromosome sequences precluded conclusive identification of this ancestor's age, geographic origin and migration patterns. Here, we report the va...

journal_title：Scientific reports

authors： Behar DM,Saag L,Karmin M,Gover MG,Wexler JD,Sanchez LF,Greenspan E,Kushniarevich A,Davydenko O,Sahakyan H,Yepiskoposyan L,Boattini A,Sarno S,Pagani L,Carmi S,Tzur S,Metspalu E,Bormans C,Skorecki K,Metspalu M,Roots

更新日期：2017-11-02 00:00:00

abstract：:Promoter activation drives gene transcriptional output. Here we report generating site-specifically integrated single-copy promoter transgenes and measuring their expression to indicate promoter activities at single-mRNA level. mRNA counts, Pol II density and Pol II firing rates of the Ccnb1 promoter transgene resembl...

journal_title：Scientific reports

authors： Vishnoi N,Yao J

更新日期：2017-05-18 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Robertson KE,Truong CD,Craciunescu FM,Yang JH,Chiu PL,Fromme P,Hansen DT

更新日期：2020-03-02 00:00:00

abstract：:Inter-digital capacitors (IDCs) with aerosol-deposition (AD) high-k dielectric layer were compared via simulation and measurements of bare IDCs and AD IDCs at room temperature and subjected to a post-annealing process for realizing capacitive super-sensing applications. IDCs with thin AD films can provide higher capac...

journal_title：Scientific reports

authors： Kim ES,Liang JG,Wang C,Cho MY,Oh JM,Kim NY

更新日期：2019-01-24 00:00:00

abstract：:A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

journal_title：Scientific reports

authors： Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

更新日期：2016-06-16 00:00:00

abstract：:We describe a technique for imaging single mRNAs in living cells based on fluorescent protein (FP) complementation. We employ the high affinity interaction between the bacterial phage MS2/PP7 coat proteins and their respective RNA binding motifs as an RNA scaffold to bring two halves of a split-FP together to image si...

journal_title：Scientific reports

authors： Wu B,Chen J,Singer RH

更新日期：2014-01-09 00:00:00

abstract：:Our goals was to evaluate how sentinel lymph node biopsy (SLNB) benefit neck management in patients with parotid cancer. Patients diagnosed with cN0 parotid cancer by preoperative fine needle puncture were prospectively enrolled. The neck status was evaluated by SLNB. If node metastasis was proved by SLNB, a neck diss...

journal_title：Scientific reports

authors： Pan W,Ba K,Niu X,Liu F,Fang Q

更新日期：2019-06-06 00:00:00

abstract：:Intrahepatic cholestasis induced by drug toxicity, bile salt export pump (BSEP) deficiency, or pregnancy frequently causes cholestatic liver damage, which ultimately may lead to liver fibrosis and cirrhosis. Here, the preventive and therapeutic effects of peroxisome proliferator-activated receptor α (PPARα) signaling ...

journal_title：Scientific reports

authors： Zhao Q,Yang R,Wang J,Hu DD,Li F

更新日期：2017-08-30 00:00:00

abstract：:Inelastic electron tunneling spectroscopy is a powerful technique for investigating lattice dynamics of nanoscale systems including graphene and small molecules, but establishing a stable tunnel junction is considered as a major hurdle in expanding the scope of tunneling experiments. Hexagonal boron nitride is a pivot...

journal_title：Scientific reports

authors： Jung S,Park M,Park J,Jeong TY,Kim HJ,Watanabe K,Taniguchi T,Ha DH,Hwang C,Kim YS

更新日期：2015-11-13 00:00:00

abstract：:The patient-derived tumor xenograft (PDTX) model has become the most realistic model for preclinical studies. PDTX models of gastric cancer using surgical tissues are reported occasionally; however, the PDTX models using gastroscopic biopsies, which are best for evaluating new drugs, are unreported. In our study, a to...

journal_title：Scientific reports

authors： Zhu Y,Tian T,Li Z,Tang Z,Wang L,Wu J,Li Y,Dong B,Li Y,Li N,Zou J,Gao J,Shen L

更新日期：2015-02-25 00:00:00

abstract：:Multiple applications of genome editing by CRISPR-Cas9 necessitate stringent regulation and Cas9 variants have accordingly been generated whose activity responds to small ligands, temperature or light. However, these approaches are often impracticable, for example in clinical therapeutic genome editing in situ or gene...

journal_title：Scientific reports

authors： Suzuki T,Asami M,Patel SG,Luk LYP,Tsai YH,Perry ACF

更新日期：2018-07-03 00:00:00

abstract：:Mass spectrometry (MS) for the detection of proteins is an indispensable tool for evaluating the biological processes of the proteome. Proteomics frequently requires proteolysis of proteins into peptide fragments. Proteins can be refractory to ideal proteolysis at the sequence level rendering them difficult to analyze...

journal_title：Scientific reports

authors： Reyna C,Mba Medie F,Champion MM,Champion PA

更新日期：2016-09-14 00:00:00

abstract：:Mast cells act as sensors in innate immunity and as effector cells in adaptive immune reactions. Here we demonstrate that SLC10A4, also referred to as the vesicular aminergic-associated transporter, VAAT, modifies mast cell degranulation. Strikingly, Slc10a4 -/- bone marrow-derived mast cells (BMMCs) had a significant...

journal_title：Scientific reports

authors： Pettersson H,Zarnegar B,Westin A,Persson V,Peuckert C,Jonsson J,Hallgren J,Kullander K

更新日期：2017-04-24 00:00:00

abstract：:Microbubble contrast agents are widely used in ultrasound imaging and therapy, typically with transmission center frequencies in the MHz range. Currently, an ultrasound center frequency near 250 kHz is proposed for clinical trials in which ultrasound combined with microbubble contrast agents is applied to open the blo...

journal_title：Scientific reports

authors： Ilovitsh T,Ilovitsh A,Foiret J,Caskey CF,Kusunose J,Fite BZ,Zhang H,Mahakian LM,Tam S,Butts-Pauly K,Qin S,Ferrara KW

更新日期：2018-11-05 00:00:00

abstract：:We have demonstrated a 45 μm core diameter Neodymium-doped all-solid silicate glass photonic crystal fiber laser with a single mode laser output. The structure parameters and modes information of the fiber are both demonstrated by theoretical calculations using Finite Difference Time Domain (FDTD) method and experimen...

journal_title：Scientific reports

authors： Li W,Chen D,Qinling Z,Hu L

更新日期：2015-07-24 00:00:00