The genetic variation in the R1a clade among the Ashkenazi Levites' Y chromosome.

Abstract:

:Approximately 300,000 men around the globe self-identify as Ashkenazi Levites, of whom two thirds were previously shown to descend from a single male. The paucity of whole Y-chromosome sequences precluded conclusive identification of this ancestor's age, geographic origin and migration patterns. Here, we report the variation of 486 Y-chromosomes within the Ashkenazi and non-Ashkenazi Levite R1a clade, other Ashkenazi Jewish paternal lineages, as well as non-Levite Jewish and non-Jewish R1a samples. Cumulatively, the emerging profile is of a Middle Eastern ancestor, self-affiliating as Levite, and carrying the highly resolved R1a-Y2619 lineage, which was likely a minor haplogroup among the Hebrews. A star-like phylogeny, coalescing similarly to other Ashkenazi paternal lineages, ~1,743 ybp, suggests it to be one of the Ashkenazi paternal founders; to have expanded as part of the overall Ashkenazi demographic expansion, without special relation to the Levite affiliation; and to have subsequently spread to non-Ashkenazi Levites.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Behar DM,Saag L,Karmin M,Gover MG,Wexler JD,Sanchez LF,Greenspan E,Kushniarevich A,Davydenko O,Sahakyan H,Yepiskoposyan L,Boattini A,Sarno S,Pagani L,Carmi S,Tzur S,Metspalu E,Bormans C,Skorecki K,Metspalu M,Roots

doi

10.1038/s41598-017-14761-7

subject

Has Abstract

pub_date

2017-11-02 00:00:00

pages

14969

issue

1

issn

2045-2322

pii

10.1038/s41598-017-14761-7

journal_volume

7

pub_type

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