An optimal distance cutoff for contact-based Protein Structure Networks using side-chain centers of mass.

abstract：:Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electri...

journal_title：Scientific reports

authors： Zhu N,Yu N,Zhu Y,Wei Y,Hou Y,Zhang H,Sun AD

更新日期：2018-05-25 00:00:00

abstract：:It has been recently ascribed to several inflammatory cytokines (i.e. TGF-β3, TNF-α, and IL-1) a functional role in regulating Sertoli cell blood-testis barrier (BTB) dynamics. In the testis, IL-6 inhibits meiotic DNA synthesis during the seminiferous epithelium cycle, reduces sperm motility and influences the secreti...

journal_title：Scientific reports

authors： Zhang H,Yin Y,Wang G,Liu Z,Liu L,Sun F

更新日期：2014-03-03 00:00:00

abstract：:Chronic kidney disease (CKD) progresses to end-stage renal failure via renal tubulointerstitial fibrosis. Malnutrition, inflammation, and arteriosclerosis interact to exacerbate the poor prognosis of CKD, and their effective management is thus essential. The traditional Japanese medicine Rikkunshito (RKT) exerts appet...

journal_title：Scientific reports

authors： Wakui H,Yamaji T,Azushima K,Uneda K,Haruhara K,Nakamura A,Ohki K,Kinguchi S,Kobayashi R,Urate S,Suzuki T,Kamimura D,Minegishi S,Ishigami T,Kanaoka T,Matsuo K,Miyazaki T,Fujikawa T,Yamashita A,Tamura K

更新日期：2020-02-05 00:00:00

abstract：:Tissue-resident memory T (TRM) cells are characterized by their surface expression of CD69 and can be subdivided in CD103+ and CD103- TRM cells. The origin and functional characteristics of TRM cells in the renal allograft are largely unknown. To determine these features we studied TRM cells in transplant nephrectomie...

journal_title：Scientific reports

authors： de Leur K,Dieterich M,Hesselink DA,Corneth OBJ,Dor FJMF,de Graav GN,Peeters AMA,Mulder A,Kimenai HJAN,Claas FHJ,Clahsen-van Groningen MC,van der Laan LJW,Hendriks RW,Baan CC

更新日期：2019-04-12 00:00:00

abstract：:Meniscal tears have a poor healing capacity, and damage to the meniscus is associated with significant pain, disability, and progressive degenerative changes in the knee joint that lead to osteoarthritis. Therefore, strategies to promote meniscus repair and improve meniscus function are needed. The objective of this s...

journal_title：Scientific reports

authors： Ruprecht JC,Waanders TD,Rowland CR,Nishimuta JF,Glass KA,Stencel J,DeFrate LE,Guilak F,Weinberg JB,McNulty AL

更新日期：2019-06-18 00:00:00

abstract：:Inappropriate sleep duration and poor sleep quality are associated with risk of stroke, but their interactive effect on stroke is unknown. We explored the interactive effect of sleep quality and duration on stroke risk. A prospective cohort study was conducted with 41,786 adults. Sleep quality was assessed using the P...

journal_title：Scientific reports

authors： Ji A,Lou H,Lou P,Xu C,Zhang P,Qiao C,Yang Q

更新日期：2020-05-26 00:00:00

abstract：:Glycan-protein lateral interactions have gained increased attention as important modulators of receptor function, by regulating surface residence time and endocytosis of membrane glycoproteins. The pathogen-recognition receptor DC-SIGN is highly expressed at the membrane of antigen-presenting dendritic cells, where it...

journal_title：Scientific reports

authors： Te Riet J,Joosten B,Reinieren-Beeren I,Figdor CG,Cambi A

更新日期：2017-07-27 00:00:00

abstract：:Dysregulation in acetylation homeostasis has been implicated in the pathogenesis of the amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder. It is known that the acetylation of transcriptional factors regulates their activity. The acetylation state of NF-kB RelA has been found to dictate the neurop...

journal_title：Scientific reports

authors： Schiaffino L,Bonafede R,Scambi I,Parrella E,Pizzi M,Mariotti R

更新日期：2018-08-27 00:00:00

abstract：:Life-history theory predicts that current behaviour affects future reproduction, implying that animals should optimise their escape strategies to reflect fitness costs and benefits of premature escape. Both costs and benefits of escape may change temporally with important consequences for the evolution of escape strat...

journal_title：Scientific reports

authors： Mikula P,Díaz M,Albrecht T,Jokimäki J,Kaisanlahti-Jokimäki ML,Kroitero G,Møller AP,Tryjanowski P,Yosef R,Hromada M

更新日期：2018-09-18 00:00:00

abstract：:The values of physiological indices and the enzymes activities involved in the overwintering stage were studied in D. armandi larvae in each month from October 2014 to March 2015. The sorbitol, trehalose and glycerol values initially tended to increase as the ambient temperature decreased, before declining until the e...

journal_title：Scientific reports

authors： Wang J,Zhang RR,Gao GQ,Ma MY,Chen H

更新日期：2016-10-05 00:00:00

abstract：:Accurate and precise structural ensembles of proteins and macromolecular complexes can be obtained with metainference, a recently proposed Bayesian inference method that integrates experimental information with prior knowledge and deals with all sources of errors in the data as well as with sample heterogeneity. The s...

journal_title：Scientific reports

authors： Bonomi M,Camilloni C,Vendruscolo M

更新日期：2016-08-26 00:00:00

abstract：:The rational synthesis of alternative materials is highly demanding due to the outbreak of infectious diseases and resistance to antibiotics. Herein, we report a tailored nanoantibiotic synthesis protocol where the antibiotic binding was optimized on the silver-silica core-shell nanoparticles surface to maximize biolo...

journal_title：Scientific reports

authors： de Oliveira JFA,Saito Â,Bido AT,Kobarg J,Stassen HK,Cardoso MB

更新日期：2017-05-02 00:00:00

abstract：:Negative hemodynamic response has been widely reported in blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging studies, however its origin is still controversial. Optical intrinsic signal (OIS) imaging can be used to study brain activity by simultaneously recording hemodynamic signals at diff...

journal_title：Scientific reports

authors： Ma Z,Cao P,Sun P,Zhao L,Li L,Tong S,Lu Y,Yan Y,Chen Y,Chai X

更新日期：2016-02-10 00:00:00

abstract：:Plutonium and radiocaesium are hazardous contaminants released by the Fukushima Daiichi nuclear power plant (FDNPP) disaster and their distribution in the environment requires careful characterisation using isotopic information. Comprehensive spatial survey of 134Cs and 137Cs has been conducted on a regular basis sinc...

journal_title：Scientific reports

authors： Dunne JA,Martin PG,Yamashiki Y,Ang IXY,Scott TB,Richards DA

更新日期：2018-11-14 00:00:00

abstract：:The influence of meteorological determinants on tuberculosis (TB) incidence remains severely under-discussed, especially through the perspective of time series analysis. In the current study, we used a distributed lag nonlinear model (DLNM) to analyze a 10-year series of consecutive surveillance data. We found that, a...

journal_title：Scientific reports

authors： Xiao Y,He L,Chen Y,Wang Q,Meng Q,Chang W,Xiong L,Yu Z

更新日期：2018-07-03 00:00:00

abstract：:Patients with Type-2 Diabetes Mellitus (T2DM) have a considerably higher risk of developing mild cognitive impairment (MCI) and dementia. The initial symptoms are very insidious at onset. We investigated the alterations in spontaneous brain activity and network connectivity through regional homogeneity (ReHo) and grap...

journal_title：Scientific reports

authors： Xiong Y,Chen X,Zhao X,Fan Y,Zhang Q,Zhu W

更新日期：2020-12-04 00:00:00

abstract：:We investigated the cognitive and behavioral profile of three distinct groups of epilepsies with a genetic background for intergroup differences: (1) idiopathic/genetic generalized epilepsies (IGE/GGE group); (2) idiopathic focal epilepsies (IFE group); and (3) epilepsies with proven or strongly suggested monogenic or...

journal_title：Scientific reports

authors： Moorhouse FJ,Cornell S,Gerstl L,Tacke M,Roser T,Heinen F,Bonfert M,von Stülpnagel C,Wagner M,Borggraefe I

更新日期：2020-12-09 00:00:00

abstract：:Small-molecule inhibitors of non-canonical IκB kinases TANK-binding kinase 1 (TBK1) and IκB kinase ε (IKKε) have shown to stimulate β-cell regeneration in multiple species. Here we demonstrate that TBK1 is predominantly expressed in β-cells in mammalian islets. Proteomic and transcriptome analyses revealed that geneti...

journal_title：Scientific reports

authors： Jia YF,Jeeva S,Xu J,Heppelmann CJ,Jang JS,Slama MQ,Tapadar S,Oyelere AK,Kang SM,Matveyenko AV,Peterson QP,Shin CH

更新日期：2020-11-09 00:00:00

abstract：:Renewable natural resources, such as solar radiation, rainfall, wind, and geothermal heat, together with ecosystem services, provide the elementary supports for the sustainable development of human society. To improve regional sustainability, we studied the spatial distributions and quantities of renewable natural res...

journal_title：Scientific reports

authors： Wang C,Zhang S,Yan W,Wang R,Liu J,Wang Y

更新日期：2016-11-18 00:00:00

abstract：:There is a growing appreciation for the diverse regulatory consequences of the family of proteins that bind to the secondary channel of E. coli RNA polymerase (RNAP), such as GreA, GreB or DksA. Similar binding sites could suggest a competition between them. GreA is characterised to rescue stalled RNAP complexes due t...

journal_title：Scientific reports

authors： Fernández-Coll L,Potrykus K,Cashel M,Balsalobre C

更新日期：2020-09-30 00:00:00

abstract：:We study the dynamics of an ultrafast single photon pulse in a one-dimensional waveguide two-point coupled with a Jaynes-Cummings system. We find that for any single photon input the transmissivity depends periodically on the separation between the two coupling points. For a pulse containing many plane wave components...

journal_title：Scientific reports

authors： Wang Y,Zhang Y,Zhang Q,Zou B,Schwingenschlogl U

更新日期：2016-09-22 00:00:00

abstract：:Erythropoiesis is regulated by the erythropoietin receptor (EpoR) binding to its ligand. The transmembrane domain (TMD) and the juxtamembrane (JM) regions of the EpoR are important for signal transduction across the cell membrane. We report a solution NMR study of the mouse erythropoietin receptor (mEpoR) comprising t...

journal_title：Scientific reports

authors： Li Q,Wong YL,Yueqi Lee M,Li Y,Kang C

更新日期：2015-08-28 00:00:00

abstract：:Increasing influence of Atlantic water in the Arctic Ocean has the potential to significantly impact regional water temperature and salinity. Here we use a rDNA barcoding approach to reveal how microbial communities are partitioned into distinct assemblages across a gradient of Atlantic-Polar Water influence in the No...

journal_title：Scientific reports

authors： Carter-Gates M,Balestreri C,Thorpe SE,Cottier F,Baylay A,Bibby TS,Moore CM,Schroeder DC

更新日期：2020-11-06 00:00:00

abstract：:Several studies have investigated the association between polymorphisms in protamine 1 and 2 genes and male infertility risk, with inconsistent results to date. This meta-analysis based on the 13 published case-control studies, including 7350 cases and 6167 controls, was performed to further establish the potential as...

journal_title：Scientific reports

authors： Jiang W,Sun H,Zhang J,Zhou Q,Wu Q,Li T,Zhang C,Li W,Zhang M,Xia X

更新日期：2015-10-16 00:00:00

abstract：:Metamaterial full-sized absorber structures are numerically and experimentally investigated in GHz region and then examined in THz frequency. By manipulating monitoring the number and the position of the defect elements in conventional unit cells, the optimal integrative absorber structures are generated. The proposed...

journal_title：Scientific reports

authors： Tran MC,Le DH,Pham VH,Do HT,Le DT,Dang HL,Vu DL

更新日期：2018-06-22 00:00:00

abstract：:Nanostructure based color filtering has been considered an attractive replacement for current colorant pigmentation in the display technologies, in view of its increased efficiencies, ease of fabrication and eco-friendliness. For such structural filtering, iridescence relevant to its angular dependency, which poses a ...

journal_title：Scientific reports

authors： Shrestha VR,Lee SS,Kim ES,Choi DY

更新日期：2014-05-12 00:00:00

abstract：:Light beams with extraordinary spatial structures, such as the Airy beam (AB), the Bessel-Gaussian beam (BGB) and the Laguerre-Gaussian beam (LGB), are widely studied and applied in many optical scenarios. We report on preparation of light beams with controllable spatial structures through sum frequency generation (SF...

journal_title：Scientific reports

authors： Zhou ZY,Li Y,Ding DS,Jiang YK,Zhang W,Shi S,Shi BS,Guo GC

更新日期：2014-07-10 00:00:00

abstract：:Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings in severe COVID-19 pneumonia patients. A cross-sectional study was conducted on 46 patients a...

journal_title：Scientific reports

authors： Pirraglia MP,Ceccarelli G,Cerini A,Visioli G,d'Ettorre G,Mastroianni CM,Pugliese F,Lambiase A,Gharbiya M

更新日期：2020-10-15 00:00:00

abstract：:Within year individual variation in the timing of seasonal reproduction within wild bird populations in highly seasonal environments can be pronounced, but the molecular and physiological mechanisms responsible for this variation are unclear. We investigated the relationship between Clock gene poly-Q length, activatio...

journal_title：Scientific reports

authors： Zhang S,Xu X,Wang W,Yang W,Liang W

更新日期：2017-11-03 00:00:00

abstract：:The occurrence of biochemical alterations that last for a long period of time in diabetic individuals even after adequate handling of glycemia is an intriguing phenomenon named metabolic memory. In this study, we show that a kidney pathway is gradually altered during the course of diabetes and remains persistently cha...

journal_title：Scientific reports

authors： de Oliveira AA,de Oliveira TF,Bobadilla LL,Garcia CC,Berra CM,de Souza-Pinto NC,Medeiros MH,Di Mascio P,Zatz R,de M Loureiro AP

更新日期：2017-01-12 00:00:00