Skin autofluorescence is increased in young people with type 1 diabetes exposed to secondhand smoking.

abstract：BACKGROUND:  Diabetic peripheral neuropathy (DPN) is one of the complications of type 2 diabetes mellitus (T2DM) that decreases the quality of life of T2DM patients. Very few studies have found an association between the development and progression of DPN in T2DM and angiotensin-converting enzyme (ACE) gene insertion/d...

journal_title：Journal of diabetes

authors： Mansoor Q,Javaid A,Bilal N,Ismail M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:With the current obesity epidemic, the search for effective weight loss approaches is required. In the present study, changes in weight, body composition and cardiovascular (CV) risk in response to a low-fat, reduced-energy diet (LFRE), a low-carbohydrate/high-protein diet (LCHP), or a commercially available...

journal_title：Journal of diabetes

authors： Rolland C,Hession M,Murray S,Wise A,Broom I

更新日期：2009-09-01 00:00:00

abstract：:Pancreatic β-cells secrete insulin when blood glucose levels become high; however, when β-cells are chronically exposed to hyperglycemia, β-cell function gradually deteriorates, which is known as β-cell glucose toxicity. In the diabetic state, nuclear expression of the pancreatic transcription factors pancreatic and d...

journal_title：Journal of diabetes

authors： Kaneto H,Matsuoka TA,Kimura T,Obata A,Shimoda M,Kamei S,Mune T,Kaku K

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Currently, there is no consensus regarding the medical treatment of chronic Charcot neuroarthropathy (CN) of foot, except for effective off-loading. Because tarsal bones are predominantly trabecular, teriparatide may improve the macroarchitecture of foot bones in chronic CN. METHODS:People with diabetes and...

journal_title：Journal of diabetes

authors： Rastogi A,Hajela A,Prakash M,Khandelwal N,Kumar R,Bhattacharya A,Mittal BR,Bhansali A,Armstrong DG

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Proprotein convertase subtilisin/kexin-type 9 (PCSK9) downregulates clearance of plasma cholesterol by liver. Its inactivation increases this clearance, reducing cardiovascular risk. However, a lack of PCSK9 could also lead to cholesterol accumulation in pancreatic islet beta cells, impairing insulin secreti...

journal_title：Journal of diabetes

authors： Mbikay M,Sirois F,Gyamera-Acheampong C,Wang GS,Rippstein P,Chen A,Mayne J,Scott FW,Chrétien M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Diabetes is a risk factor for various cancers, but its prognostic role in renal cell carcinoma (RCC) is controversial and understudied. This study investigated the prognostic value of type 2 diabetes (T2D) in RCC patients. METHODS:The clinicopathological and follow-up data of 451 RCC patients undergoing rad...

journal_title：Journal of diabetes

authors： Yang H,Yin K,Wang Y,Xia M,Zhang R,Wang W,Chen J,Wang C,Shuang W

更新日期：2019-12-01 00:00:00

abstract：:Adenosine triphosphate (ATP) synthesis and release in mitochondria play critical roles in regulating insulin secretion in pancreatic β cells. Mitochondrial dysfunction is mainly characterized by a decrease in ATP production, which is a central event in the progression of pancreatic β cell dysfunction and diabetes. ATP...

journal_title：Journal of diabetes

authors： Wang C,Geng B,Cui Q,Guan Y,Yang J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) treatment generally requires multiple antihyperglycemic agents. When diet, exercise, and treatment with sulfonylurea and metformin do not achieve glycemic goals, several options are available. The present study evaluated the efficacy and tolerability of sitagliptin 100 mg/day ...

journal_title：Journal of diabetes

authors： Moses RG,Round E,Shentu Y,Golm GT,O'neill EA,Gantz I,Engel SS,Kaufman KD,Goldstein BJ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:An increase in the prevalence of type 2 diabetes mellitus occurs in immigrants from developing regions to Western countries. However, the dynamics of these transitions in relation to the duration of residence in the new environment are not clearly defined. METHODS:Data concerning cardiovascular risk factors...

journal_title：Journal of diabetes

authors： Kalchiem-Dekel O,Shai I,Biderman A,Orenstein A,Cicurel A,Reuven Y,Henkin Y

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Brown adipose tissue (BAT) has been regarded as a potential target organ to combat obesity and related metabolic disorders. However, the effect of BAT activation on the development of diabetic kidney disease (DKD) remains unclear. METHODS:Diabetic mice were induced by streptozotocin (STZ) combined with a hi...

journal_title：Journal of diabetes

authors： Cai YY,Zhang HB,Fan CX,Zeng YM,Zou SZ,Wu CY,Wang L,Fang S,Li P,Xue YM,Guan MP

更新日期：2019-12-01 00:00:00

abstract：:Observations from clinical studies suggest that low serum levels of testosterone in men are often associated with obesity, insulin resistance, and metabolic compromise. Indeed, the clinical symptoms of late-onset hypogonadism are markedly similar to those of Type 2 diabetes mellitus (T2DM) and metabolic syndrome, and ...

journal_title：Journal of diabetes

authors： Jones TH

更新日期：2010-09-01 00:00:00

abstract：:The 2011 United Nations political declaration against non-communicable diseases (NCDs) targeted four major risk factors: tobacco use, harmful use of alcohol, an unhealthy diet, and a lack of physical activity. The Framework Convention on Tobacco Control (FCTC), MPOWER strategies, and the four-stage model of the tobacc...

journal_title：Journal of diabetes

authors： Xu L,Lam TH

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Self-efficacy plays a critical role in diabetes self-care. Herein we explore factors contributing to decreased insulin therapy self-efficacy in insulin-naïve patients with type 2 diabetes mellitus (T2DM) initiating and managing insulin therapy over 36 weeks. METHODS:The study was conducted within an interna...

journal_title：Journal of diabetes

authors： Hayes RP,Curtis B,Ilag L,Nelson DR,Wong M,Funnell M

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Some reports suggest that concentrations of vitamin D are inversely, whereas concentrations of parathyroid hormone (PTH) are directly, associated with prevalent metabolic syndrome. Because of lingering uncertainty about these associations, we examined the cross-sectional associations between serum concentrat...

journal_title：Journal of diabetes

authors： Ford ES,Zhao G,Li C,Pearson WS

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate whether the therapeutic efficacy of acarbose and metformin is correlated with baseline HbA1c levels in Chinese patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Data for 711 subjects were retrieved from the MARCH (Metformin and AcaRbose in...

journal_title：Journal of diabetes

authors： Zhang JP,Wang N,Xing XY,Yang ZJ,Wang X,Yang WY

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:There is little information on medication use, trends across time, and the impact of guidelines on appropriate use of antidiabetic drugs in participants with type 2 diabetes mellitus (T2DM) with chronic kidney disease (CKD). METHODS:A cross-sectional analysis of the National Health and Nutrition Examination...

journal_title：Journal of diabetes

authors： Gor D,Gerber BS,Walton SM,Lee TA,Nutescu EA,Touchette DR

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Limited information exists regarding the efficacy of pregabalin in Chinese patients with painful diabetic peripheral neuropathy (pDPN). METHODS:An 11-week double-blind placebo-controlled trial was performed in Chinese pDPN patients randomized (1 : 1) to 300 mg/day pregabalin or placebo. The primary outcome ...

journal_title：Journal of diabetes

authors： Mu Y,Liu X,Li Q,Chen K,Liu Y,Lv X,Xu X,Fan D,Shang N,Yang R,Pauer L,Pan C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Although niacin often has beneficial effects on the lipoprotein profile, flushing is an untoward effect associated with its use. Aspirin can only reduce the flushing response by 30-40%. Thus, the aim of the present study was to investigate the mechanisms of niacin-induced flushing, with and without aspirin, ...

journal_title：Journal of diabetes

authors： Parson HK,Harati H,Cooper D,Vinik AI

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:A1c, a surrogate measure of glycemic control, is known to have a strong linear correlation with mean plasma glucose (MPG) when analyzed in populations of patients. However, clinically significant intersubject variability in this relationship exists, which suggests that A1c measurements may not reflect actual...

journal_title：Journal of diabetes

authors： Shrom D,Sarwat S,Ilag L,Bloomgarden ZT

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have reported a close association between serum lipopolysaccharide-binding protein (LBP) and many metabolic disorders. However, no longitudinal study has explored the relationship between LBP and type 2 diabetes mellitus (T2DM). The aim of the present study was to investigate the asso...

journal_title：Journal of diabetes

authors： Zhou H,Hu J,Zhu Q,Yang S,Zhang Y,Gao R,Liu L,Wang Y,Zhen Q,Lv Q,Li Q

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the effect of a new self-care guide package on gestational diabetes mellitus (GDM). METHODS:This randomized clinical trial was conducted on 152 women with GDM. The intervention group was provided with the self-care guide package and three face-to-face educational sessi...

journal_title：Journal of diabetes

authors： Kolivand M,Rahimi MA,Keramat A,Shariati M,Emamian MH

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Adipocyte fatty acid-binding protein (A-FABP) has been recognized as an important player in macrophage cholesterol trafficking and inflammation, and may promote the development of atherosclerosis. To further elucidate the role of A-FABP in atherosclerosis in diabetes, we investigated the relationship between...

journal_title：Journal of diabetes

authors： Ding M,Shi JY,Xing YZ,Sun B,Fang QH,Zhang JY,Zhang QM,Chen LM,Yu DM,Li CJ

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To investigate carbohydrate antigen (CA) 19-9 levels in subjects with different glucose regulation status and assess the relationship between CA 19-9 and glucose regulation status in a Chinese population aged 40 years and older. METHODS:A total of 2792 participants aged 40 years or older with no history of d...

journal_title：Journal of diabetes

authors： Huang Y,Xu Y,Bi Y,Xu M,Lu J,Wang T,Li M,Chen Y,Liu Y,Huang F,Xu B,Zhang J,Wang W,Ning G

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Atherosclerosis may be stimulated by the increased presence of insulin and tumor necrosis-factor-α (TNFα) with subsequent expression of vascular cell adhesion molecule-1 (VCAM-1). We hypothesized that extracellular signal-regulated kinase-5 (ERK5) plays an important role in insulin and TNFα-stimulated total ...

journal_title：Journal of diabetes

authors： Mackesy DZ,Goalstone ML

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The present study investigated the correlation between urinary α1 -microglobulin as a marker of tubular dysfunction and albumin excretion in children and adolescents with type 1 diabetes (T1D). METHODS:Ninety-two Egyptian patients with T1D were included in the study (mean [± SD] age 14.14 ± 5.13 years). The...

journal_title：Journal of diabetes

authors： Saif A,Soliman N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Obesity and shorter telomeres increase the risk for diabetes complications and mortality. However, the relationship between obesity and telomere length in diverse Asian populations with type 2 diabetes (T2D) is not well understood. This study examined the association of baseline and changes in obesity indice...

journal_title：Journal of diabetes

authors： Gurung RL,M Y,Liu S,Liu JJ,Chan SM,Moh MC,Ang K,Tang WE,Sum CF,Tavintharan S,Lim SC,SMART2D Study.

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...

journal_title：Journal of diabetes

authors： Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WY

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Considerable uncertainty remains about obstructive lung function( OLF) in adults with metabolic syndrome (MetS). The aim of the present study was to examine pulmonary function status in adults with and without MetS. METHODS:We used data from 3109 participants aged ≥20 years of the National Health and Nutrit...

journal_title：Journal of diabetes

authors： Ford ES,Cunningham TJ,Mercado CI

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Supervised treadmill exercise is the recommended therapy for peripheral arterial disease (PAD) patients with intermittent claudication (IC). However, most PAD patients do not exhibit typical symptoms of IC. The aim of the present study was to explore the efficacy and safety of intensive walking exercise in P...

journal_title：Journal of diabetes

authors： Lyu X,Li S,Peng S,Cai H,Liu G,Ran X

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Elevated blood or urinary concentrations of endocrine-disrupting chemicals (EDCs) may be related to increased risk of type 2 diabetes (T2D). The aim of the present study was to assess the role of EDCs in affecting risk of T2D and related metabolic traits. METHODS:MEDLINE was searched for cross-sectional and...

journal_title：Journal of diabetes

authors： Song Y,Chou EL,Baecker A,You NC,Song Y,Sun Q,Liu S

更新日期：2016-07-01 00:00:00