Abstract:
:The 2011 United Nations political declaration against non-communicable diseases (NCDs) targeted four major risk factors: tobacco use, harmful use of alcohol, an unhealthy diet, and a lack of physical activity. The Framework Convention on Tobacco Control (FCTC), MPOWER strategies, and the four-stage model of the tobacco epidemic are useful references for the prevention and control of other risk factors and NCDs. Obesity control is a more complex challenge. Herein we propose a stage of obesity epidemic model (SOEM). Obesity is in the early stages in most countries with increasing prevalence, but its effects on mortality will increase rapidly, even if its prevalence may have reached a peak and be declining. Based on current relative risk, obesity kills one in three obese people. Like tobacco, epidemiological studies of obesity in the early stages would underestimate the risks and disease burden. Further research will reveal more harm, especially from long-term obesity since childhood. The prevalence of obesity will likely overtake smoking prevalence, but commitments to obesity control are too weak. The SOEM is needed and should be useful to forewarn against the expanding public health problems attributable to obesity, and challenges in epidemiology and interventions. Learning from tobacco control, we advocate for a framework convention on obesity control. Framing obesity control initiatives in the spirit of MPOWER strategies against tobacco should be considered to prevent and control obesity and obesity-induced diseases. Healthcare professionals should take leading roles in these initiatives and obese individuals should reduce their weight and "quit" obesity.
journal_name
J Diabetesjournal_title
Journal of diabetesauthors
Xu L,Lam THdoi
10.1111/1753-0407.12647subject
Has Abstractpub_date
2018-07-01 00:00:00pages
564-571issue
7eissn
1753-0393issn
1753-0407journal_volume
10pub_type
杂志文章,评审abstract:BACKGROUND:Proprotein convertase subtilisin/kexin-type 9 (PCSK9) downregulates clearance of plasma cholesterol by liver. Its inactivation increases this clearance, reducing cardiovascular risk. However, a lack of PCSK9 could also lead to cholesterol accumulation in pancreatic islet beta cells, impairing insulin secreti...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12139
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Few studies have focused on postprandial incretin responses to different carbohydrate meals. Therefore, we designed a study to compare the different effects of two carbohydrates (75 g oral glucose, a monosaccharide and 100 g standard noodle, a polysaccharide, with 75 g carbohydrates equivalently) on postpran...
journal_title:Journal of diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1111/1753-0407.12245
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic β-cells are destroyed by infiltrating immune cells. Bilateral cooperation of pancreatic β-cells and immune cells has been proposed in the progression of T1D, but as yet no systems study has investigated this possibility. The aims of the study...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12483
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12078
更新日期:2014-05-01 00:00:00
abstract::There has been a rapid escalation of type 2 diabetes (T2D) in developing countries, with varied prevalence according to rural vs urban habitat and degree of urbanization. Some ethnic groups (eg, South Asians, other Asians, and Africans), develop diabetes a decade earlier and at a lower body mass index than Whites, hav...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12913
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Uncontrolled diabetes mellitus causes neuronal damage because of increased intracellular glucose. Natural products as complementary therapy may reduce neuronal complications. This study investigated whether fish oil (FO) and wheat germ oil (WGO) supplementation protects the brain in streptozotocin (STZ)-indu...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12518
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:It is clear that aerobic training (AT) can delay pancreatic exhaustion and slow the progression from prediabetes to type 2 diabetes (T2D), but there is little information regarding the effects of resistance training (RT) in people with prediabetes. This study compared the effectiveness of RT and AT in improv...
journal_title:Journal of diabetes
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/1753-0407.12955
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The aims of the present study were to examine the association of cigarette smoking and alcohol consumption with impaired β-cell function in Chinese men, particularly the interaction of smoking and alcohol consumption on impaired insulin secretion. METHODS:A population-based cross-sectional study was perform...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12314
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Diabetes is a risk factor for various cancers, but its prognostic role in renal cell carcinoma (RCC) is controversial and understudied. This study investigated the prognostic value of type 2 diabetes (T2D) in RCC patients. METHODS:The clinicopathological and follow-up data of 451 RCC patients undergoing rad...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12957
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Some reports suggest that concentrations of vitamin D are inversely, whereas concentrations of parathyroid hormone (PTH) are directly, associated with prevalent metabolic syndrome. Because of lingering uncertainty about these associations, we examined the cross-sectional associations between serum concentrat...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2009.00046.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:To evaluate the association between thyroid autoimmunity and psychiatric disorders (depression, anxiety, eating disorder, schizophrenia or attention-deficit/hyperactivity disorder) among adolescents and young adults with type 1 diabetes (11-25 years). METHODS:We compared 9368 type 1 diabetes patients with t...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13145
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:Although niacin often has beneficial effects on the lipoprotein profile, flushing is an untoward effect associated with its use. Aspirin can only reduce the flushing response by 30-40%. Thus, the aim of the present study was to investigate the mechanisms of niacin-induced flushing, with and without aspirin, ...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2012.00216.x
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:An increase in the prevalence of type 2 diabetes mellitus occurs in immigrants from developing regions to Western countries. However, the dynamics of these transitions in relation to the duration of residence in the new environment are not clearly defined. METHODS:Data concerning cardiovascular risk factors...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12215
更新日期:2015-07-01 00:00:00
abstract::Adenosine triphosphate (ATP) synthesis and release in mitochondria play critical roles in regulating insulin secretion in pancreatic β cells. Mitochondrial dysfunction is mainly characterized by a decrease in ATP production, which is a central event in the progression of pancreatic β cell dysfunction and diabetes. ATP...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12098
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12497
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:The present study investigated the correlation between urinary α1 -microglobulin as a marker of tubular dysfunction and albumin excretion in children and adolescents with type 1 diabetes (T1D). METHODS:Ninety-two Egyptian patients with T1D were included in the study (mean [± SD] age 14.14 ± 5.13 years). The...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12383
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Cross-sectional studies have reported a close association between serum lipopolysaccharide-binding protein (LBP) and many metabolic disorders. However, no longitudinal study has explored the relationship between LBP and type 2 diabetes mellitus (T2DM). The aim of the present study was to investigate the asso...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12281
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2012.00227.x
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Cross-sectional studies have supported the association among depression, obesity, and type 2 diabetes, but the causality remains controversial in Chinese adults. In this longitudinal study, we evaluated the synergistic effect of depression and obesity on the risk of type 2 diabetes. METHODS:This study inclu...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12968
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Women with previous gestational diabetes mellitus (pGDM) are at increased risk of developing type 2 diabetes later in life. The aim of this study was to determine if circulating levels of metabolic hormones 12 weeks following a GDM pregnancy are associated with an increased risk of type 2 diabetes 8-10 years...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12209
更新日期:2015-07-01 00:00:00
abstract::Glucagon-like peptide-1 (GLP-1) is the primary incretin hormone secreted from the intestine upon uptake of food to stimulate insulin secretion from pancreatic β-cells. GLP-1 exerts its effects by binding to its G-protein coupled receptors and subsequently activating adenylate cyclase, leading to generation of cyclic a...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12161
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome (MetS) is highly prevalent worldwide, and its individual components obesity, diabetes, and hypertension have been identified as risk factors to develop severe coronavirus disease 2019 (COVID-19); however, data on MetS and clinical outcomes in COVID-19 are scarce. This study aims to determi...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13157
更新日期:2021-01-16 00:00:00
abstract:BACKGROUND:Although diabetes is associated with ethnicity and worse cardiac surgery outcomes, no research has been done to study the effect of both diabetes and ethnicity on cardiac surgery outcomes in a multiethnic Southeast Asian cohort. Hence, this study aimed to delineate the association of ethnicity on outcomes af...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12961
更新日期:2020-01-01 00:00:00
abstract::Diabetes mellitus is a metabolic disease with a considerable impact on healthcare owing to its increased prevalence and high mortality rate. Structural, morphological, and physiological changes in each of the ocular components have been described in detail. Autofluorescence has been described as a good indicator of me...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12423
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:There is little information on medication use, trends across time, and the impact of guidelines on appropriate use of antidiabetic drugs in participants with type 2 diabetes mellitus (T2DM) with chronic kidney disease (CKD). METHODS:A cross-sectional analysis of the National Health and Nutrition Examination...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13003
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the effect of a new self-care guide package on gestational diabetes mellitus (GDM). METHODS:This randomized clinical trial was conducted on 152 women with GDM. The intervention group was provided with the self-care guide package and three face-to-face educational sessi...
journal_title:Journal of diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1111/1753-0407.12827
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to develop a simple nomogram that can be used to predict the risk of diabetes mellitus (DM) in the asymptomatic non-diabetic subjects based on non-laboratory- and laboratory-based risk algorithms. METHODS:Anthropometric data, plasma fasting glucose, full lipid profile, exerc...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12310
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To investigate carbohydrate antigen (CA) 19-9 levels in subjects with different glucose regulation status and assess the relationship between CA 19-9 and glucose regulation status in a Chinese population aged 40 years and older. METHODS:A total of 2792 participants aged 40 years or older with no history of d...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2011.00179.x
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The effect of postload glucose spikes (PGS), the difference between 2 hour post-load plasma glucose (2hPLPG) and fasting plasma glucose (FPG), on post-myocardial infarction (post-MI) prognosis in nondiabetic patients is unexplored. METHODS:This is a retrospective cohort analysis of 847 nondiabetic post-MI s...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13111
更新日期:2021-03-01 00:00:00
abstract::Islet transplantation is an attractive concept for the treatment of Type 1 diabetes because of its potential high efficacy and minimal invasion to patients. The treatment may effectively control blood glucose for brittle Type 1 diabetes, resulting in a marked reduction in hypoglycemic episodes and improvements in HbA1...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2009.00048.x
更新日期:2010-03-01 00:00:00