Abstract:
BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asians living in Singapore and Mauritius to determine the contribution of ethnicity and economic development to diabetes. METHODS:Age-specific data from serial national population-based surveys in Singapore and Mauritius between 1987 and 2010 were used to estimate age-standardized diabetes and obesity prevalence. Modified Breslow-Cox proportional hazard models were used to obtain rate ratios for diabetes risk factors. RESULTS:In Singapore, the age-standardized prevalence of diabetes remained stable for Chinese (men: 14% in 1992, 13% in 2010; women: 12% in 1992, 10% in 2010), but increases were observed for South Asians (men: 20% in 1992, 26% in 2010; women: 18% in 1992, 20% in 2010). There were similar patterns in Mauritius. In both countries, obesity prevalence trends were stable for Chinese women, but increased for Chinese men and South Asians. Associations between obesity and diabetes were stronger in Chinese than South Asians regardless of country. CONCLUSIONS:Despite different socioeconomic settings in Singapore and Mauritius, we observed rising diabetes prevalence among South Asians but stable prevalence in Chinese in both countries. This provides further evidence that ethnicity contributes to the development of diabetes, and that there should be an increased emphasis on future prevention strategies targeting South Asian populations in these countries.
journal_name
J Diabetesjournal_title
Journal of diabetesauthors
Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WYdoi
10.1111/1753-0407.12497subject
Has Abstractpub_date
2017-09-01 00:00:00pages
855-864issue
9eissn
1753-0393issn
1753-0407journal_volume
9pub_type
杂志文章abstract:BACKGROUND:Glucagon-like peptide-1 (GLP-1) analogues have emerged as insulin secretagogues and are widely used in type 2 diabetic patients. GLP-1 analogues also demonstrate a promotion of beta cell proliferation and reduction of apoptosis in rodents. In the present study, we investigated the protection of pancreatic be...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12061
更新日期:2013-12-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12864
更新日期:2019-05-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2021-01-16 00:00:00
abstract:BACKGROUND:There is a wide variety of dressings currently available for the treatment of diabetic foot ulcers (DFUs). Because of a lack of evidence from head-to-head randomized controlled trials (RCTs), the relative effects of these dressings in DFU patients remain unclear. This study compared the efficacy of nine dres...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12871
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:G protein-coupled receptor kinase-2 (GRK2) has been shown as a key regulator of cardiac function, and the myocardial GRK2 levels are mirrored by the levels in peripheral blood mononuclear cells (PBMCs). In this study, we evaluated the myocardial and PBMCs GRK2 levels in early diabetic cardiomyopathy (DCM). ...
journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12483
更新日期:2017-08-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2009.00046.x
更新日期:2009-12-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章,随机对照试验
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更新日期:2015-03-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12923
更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of diabetes
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of diabetes
pub_type: 信件
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更新日期:2020-01-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章,评审
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更新日期:2010-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
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journal_title:Journal of diabetes
pub_type: 信件
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更新日期:2017-03-01 00:00:00